Protein Alignment ath and hrpA

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_415931.4
• Gene: hrpA / 948444
• ECOCYCID: G6732
• Length: 1300
• Species: Escherichia coli
• Alignment Length: 660
• Identity: 228/660 - (34%)
• Similarity: 359/660 - (54%)
• Gaps: 36/660 - (5%)

  Fly    44 QIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLA 108
            :|.|....:||............:|||...:..||:.:..:..|::..|||||||||:|:..:..
E. coli    53 EIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMEL 117

  Fly   109 GYAKNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRES 173
            |....|:||.|||||:||.|||.|:|:||....|..:||.|||.|..|..|.::.:|||:||.|.
E. coli   118 GRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEI 182

  Fly   174 IKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYF- 237
            .:||||::|..||:||||||::|.|.|.|.:|:....|     .:||:::||||:|.:.|..:|
E. coli   183 QQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRR-----PDLKIIITSATIDPERFSRHFN 242

  Fly   238 NCKGMYLEGRTYPVRVMHTK--EEHEDYIHTVLVTLFH-IHRTTPKNH-DVLIFLTGQEEIESLA 298
            |...:.:.||||||.|.:..  ||.:|.....|..:|. :...:.::| |:|||::|:.||...|
E. coli   243 NAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESHGDILIFMSGEREIRDTA 307

  Fly   299 QQIRQLAKIDTTGTTDLR---VFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIR 360
            ..:.:|         :||   :..|||:||..:|...|  ...:.|:::||||:||||:|:|||:
E. coli   308 DALNKL---------NLRHTEILPLYARLSNSEQNRVF--QSHSGRRIVLATNVAETSLTVPGIK 361

  Fly   361 CVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQP 425
            .|||.|..:...::....:..|....||:|.|.||.||.||.::|.|.|.|::.:..|..:.|.|
E. coli   362 YVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDP 426

  Fly   426 EILRTNPTSMVLQLLALDI-DCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDS---YITPLGR 486
            ||||||..|::||:.||.: |...|.|::.|.:..::...:.|:.||||.|.:.:   .:|||||
E. coli   427 EILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGR 491

  Fly   487 QMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGDHL 551
            |:.|.|:||:.::::|.|...||:.|.:.:.|.||.........:|.:.:...|.:|..|..|.|
E. coli   492 QLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFL 556

  Fly   552 TLLNVFNGF------LKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHLALNSSD-DIEM 609
            ..:|::|..      |.|...:..|..:|||...:...:::..|||::.:.|.:.:||.. :...
E. coli   557 AFVNLWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYRE 621

  Fly   610 LKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVT 674
            :...:|.|...:|.:...|....|.:.|.|..|.|.|.|. |..|.:::..|:|:|.:.:.|...
E. coli   622 IHIALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLF-KKPPKWVMVAELVETSRLWGRIAA 685

  Fly   675 EISIEWIKEV 684
            .|..||::.|
E. coli   686 RIDPEWVEPV 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	224/637 (35%)
hrpA	NP_415931.4	PRK11131	5..1298	CDD:182986	228/660 (35%)