DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and Dqx1

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_291084.1	Gene:	Dqx1 / 93838	MGIID:	2136388	Length:	718	Species:	Mus musculus

Alignment Length:	687	Identity:	212/687 - (30%)
Similarity:	349/687 - (50%)	Gaps:	100/687 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 QQQKSLPVFNCRHRILKELEANDT--VLIMSETGSGKTTQIPQ----FLLLAGYAKNGMIGITQP 121
            :|:::||::..|...|:.||::.|  ||:..:.||||:|||||    |.|..|: :.|.:.:|||
Mouse    37 EQRRALPIWAARFLFLEHLESSPTGVVLVSGDPGSGKSTQIPQWCAEFALARGF-QTGQVTVTQP 100

  Fly   122 RRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVII 186
            ..:||:::|.|||.|::.|:|..:||::..||.|...|.:||..|.:.|:|....|....:||:|
Mouse   101 YPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSVLI 165

  Fly   187 LDEAHERTVNADLLFGIVKDAQKERRKQKLANLK-----VVVTSATMDIDHFGNYFNCKGMYLEG 246
            ||||.||:|.:|||.|:::|.       :|.||.     ||||...:: ..|..::        |
Mouse   166 LDEAQERSVASDLLQGLLRDT-------RLRNLPGDPRVVVVTDPALE-PKFQAFW--------G 214

  Fly   247 RTYPVRVMHTKE-------EHEDYIHTVLV-----TLFHIHRTTPKNHDVLIFLTGQEEI----E 295
            .:..|||  .:|       .::|.:.|.||     .:..:.:......|||::|..:|||    |
Mouse   215 NSPIVRV--PREPGGDPTLAYKDTVPTDLVEAACQAVLELCQQEEAPGDVLVYLPSEEEISLCCE 277

  Fly   296 SLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIR 360
            ||:.::..||   ..|... ||..|:...:|..| ..:..|..:|||:::...:|:.|.::|.|:
Mouse   278 SLSGEMGTLA---VPGPPP-RVLPLHPGCAQAIQ-TVYEDTDVSVRKIVVTHWLADFSFSLPSIQ 337

  Fly   361 CVIDCGFVKEKSFNTVDGLD--VLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFA-DA 422
            .|||.|......:|.....:  ||:.  |||.||..|..||.....|:|.|.|:|:.::..| ..
Mouse   338 HVIDSGLELRSVYNPRIRAESQVLRP--ISKCQAEARLLRAKGFPPGSCLRLYSKSTLELEAPPL 400

  Fly   423 TQPEILRTNPTSMVLQLLALDI----DCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITP 483
            ..|::...|.:|:||.|:...|    :|:   |||.|..:.|..|.:.||.|.|:  .||..::.
Mouse   401 PHPKVCEENLSSLVLLLMRKQIAEPGECH---FLDRPAPEALMRALEDLDYLAAL--NDDGELSD 460

  Fly   484 LGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVF----VSNSEKNEMAALAHAKFQ 544
            ||..:.::||.|:.:|.||.:..|.|::|:|:|.::|::...|    :|..|.....||.||
Mouse   461 LGVILSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLSAGEAALRRALEHA--- 522

  Fly   545 SKHGDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHL-----ALNSS 604
              .|||.:|:.|:..|::|...:.||....||..||..||.:|.:|.|:.:.:.|     |..|.
Mouse   523 --DGDHSSLIQVYEAFVQSGADEAWCQARGLNWESLCQARKLRAELVELMQRIELPLSQPAFGSE 585

  Fly   605 DDIEMLKKCILNGFFENIAVLQRD----GFYITASGNIRSKIHPSSVLHGKYK--------PSYI 657
            .:...|:|.:|:|:|..:|   ||    |.|:..:....:::.|    :..|:        |:::
Mouse   586 QNRRDLQKALLSGYFLKVA---RDTDGTGNYLLLTHKHVAQLSP----YCSYRNRRTPAQPPTWV 643

  Fly   658 LFTEIVQTEQTFLRQVTEISIEWIKEVVP--FVKNIP 692
            |:.....::...|..|:||..|.:.|:.|  |:.|:|
Mouse   644 LYHSFSISKDNCLCIVSEIQPEMLVELAPPYFLSNLP 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
Dqx1	NP_291084.1	HrpA	9..672	CDD:224557	208/677 (31%)
		DEAQ box	167..170		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	690..718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820