Protein Alignment ath and PRP2

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_014408.1
• Gene: PRP2 / 855745
• SGDID: S000005294
• Length: 876
• Species: Saccharomyces cerevisiae
• Alignment Length: 711
• Identity: 266/711 - (37%)
• Similarity: 411/711 - (57%)
• Gaps: 50/711 - (7%)

  Fly     8 TSRNDAVGPSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFN 72
            :.:.|.|..:.....:..:.|.:.....|:.:..:||..:|....:||     |::.:|.|||..
Yeast   168 SDKYDYVFDTDAMIDYTNEEDDLLPEEKLQYEARLAQALETEEKRILT-----IQEARKLLPVHQ 227

  Fly    73 CRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNG--MIGITQPRRVAAITVARRVAQ 135
            .:..:|:|::.|..::||.|||||||||:||:|:..|:...|  .|.|||||||||.:||.|||.
Yeast   228 YKDELLQEIKKNQVLIIMGETGSGKTTQLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARVAD 292

  Fly   136 ELNGTIGDTVGYTVRFED-VTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADL 199
            |:|..:|..|||.:|||| .|...|.::::|||:||||.:.|..|.|||.|::|||||||:..|:
Yeast   293 EMNVVLGKEVGYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDI 357

  Fly   200 LFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYF-NCKGMYLEGRTYPVRVMHTKEEHEDY 263
            |.|::||...:|     ..||::::||||:...|..:| ||....:.||.|||.:.:|.:...:|
Yeast   358 LIGLLKDILPQR-----PTLKLLISSATMNAKKFSEFFDNCPIFNVPGRRYPVDIHYTLQPEANY 417

  Fly   264 IHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGK 328
            ||..:.|:|.||.|.....|:|:|||||||||....::.::.....:.|..:.:..:||.|.|.:
Yeast   418 IHAAITTIFQIHTTQSLPGDILVFLTGQEEIERTKTKLEEIMSKLGSRTKQMIITPIYANLPQEQ 482

  Fly   329 QLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAW 393
            ||:.|.|||.|.|||:|||||||||:||.|||.|||.|||||.|:....|:..|.:|..|:|...
Yeast   483 QLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVD 547

  Fly   394 QRAGRAGRDADGTCYRAYTK-AEMDSFADATQPEILRTNPTSMVLQLLALDI-DCNNFDFLDPPL 456
            ||||||||...|.|:|.:|| :.:.......:|||.|||.::.||.||:|.: |...|..:|.|.
Yeast   548 QRAGRAGRVGPGKCFRIFTKWSYLHELELMPKPEITRTNLSNTVLLLLSLGVTDLIKFPLMDKPS 612

  Fly   457 EDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYPLDPKYSKLLLTASSF----GCMEEILSLV 517
            ...||.:.::|..|||:.:  ...||.||:.|.::|.:|:::|:|.||::.    |.:||.|::|
Yeast   613 IPTLRKSLENLYILGALNS--KGTITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIV 675

  Fly   518 SVL-SSDHVFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLT 581
            |:| .:..:|:  .:|.:.||...::.:|   ||:..|.:||.:..|:..:.||.|:.:..:::.
Yeast   676 SMLHETPSLFI--GQKRDAAASVLSEVES---DHILYLEIFNQWRNSKFSRSWCQDHKIQFKTML 735

  Fly   582 YARNVRRQLREISEHLHLALNSSDDIEM------------LKKCILNGFFENIAVLQRDGFYI-- 632
            ..||:|.||...||.:.| :..:|...|            :.:|.::||..||..|...|:..
Yeast   736 RVRNIRNQLFRCSEKVGL-VEKNDQARMKIGNIAGYINARITRCFISGFPMNIVQLGPTGYQTMG 799

  Fly   633 TASGNIRSKIHPSSVLHGKYK-----PS-YILFTEIVQTEQTFLRQVTEI-SIEWIKEVVP 686
            .:||.:...:||:|:|...:|     || |:|:.:::.|.:.|:|....| ..||:.::||
Yeast   800 RSSGGLNVSVHPTSILFVNHKEKAQRPSKYVLYQQLMLTSKEFIRDCLVIPKEEWLIDMVP 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	253/650 (39%)
PRP2	NP_014408.1	PTZ00121	<7..174	CDD:173412	1/5 (20%)
		HrpA	223..>738	CDD:441249	219/526 (42%)
		OB_NTP_bind	775..862	CDD:400182	26/86 (30%)