DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and PRP16

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_013012.3	Gene:	PRP16 / 853961	SGDID:	S000001794	Length:	1071	Species:	Saccharomyces cerevisiae

Alignment Length:	654	Identity:	268/654 - (40%)
Similarity:	390/654 - (59%)	Gaps:	34/654 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYA--KNGM 115
            |.|..:..|:..::.||||.||.::|..:..|..|:|:.|||||||||:.|:|...|||  :...
Yeast   335 LFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKS 399

  Fly   116 IGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVT-SRATKIRFLTDGVLLRESIKDRLL 179
            |.:|||||||||:||:|||.|:...:|..|||::|||||| |..||::|:|||:||||::.|..|
Yeast   400 IVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTL 464

  Fly   180 LKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYF-NCKGMY 243
            .|||.:|:||||||::|.|:|.|..|.....||     :||:::|||||:...|..:| |.....
Yeast   465 DKYSCVIIDEAHERSLNTDILLGFFKILLARRR-----DLKLIITSATMNAKKFSAFFGNAPQFT 524

  Fly   244 LEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTP-KNHDVLIFLTGQEEIE----SLAQQIRQ 303
            :.|||:||:.::|....:||:...:.....||.... .:.|:|||:||||:||    :|.::..|
Yeast   525 IPGRTFPVQTIYTSNPVQDYVEAAVSQAVKIHLANDCSSGDILIFMTGQEDIETTFDTLQEKFLQ 589

  Fly   304 L--AKIDTTG---TTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVI 363
            :  .|..|..   ..|:.:..:|:.|....|.:.|.......||:|:||||||||:||.|||.||
Yeast   590 VYSKKFGTANFEEINDIEILPIYSALPADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVI 654

  Fly   364 DCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFAD----ATQ 424
            |||:.|.|.:|...|||.|....||||.|.||:|||||.|.||.||.||:   |:|.:    .|.
Yeast   655 DCGYSKLKVYNPKIGLDSLVITPISKANADQRSGRAGRTAPGTAYRLYTE---DTFKEDMYLQTI 716

  Fly   425 PEILRTNPTSMVLQLLALDI--DCNNFDFLD-PPLEDGLRSAYKSLDALGAIKTGDDSYITPLGR 486
            |||.|||.::.:|.|.:||:  :.:.|.|:| |||:..|.|.|: |..:|||.|  ...:||||.
Yeast   717 PEIQRTNLSNTLLLLKSLDVTDELSKFPFIDKPPLQTFLSSLYE-LWFIGAIDT--SGQLTPLGL 778

  Fly   487 QMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGDHL 551
            ||.::||.|..||:||.|...||.:|:|::||:||...||....|:.:.|.:|..||.....|||
Yeast   779 QMAKFPLQPSLSKILLIAVRNGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHL 843

  Fly   552 TLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHL-ALNSSDDIEMLKKCIL 615
            ||||||..:..:.....||:.:::..:||..||::|.||..|.:...: .::|..|.:::||||.
Yeast   844 TLLNVFEQWRANNFSSHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCIC 908

  Fly   616 NGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYK-PSYILFTEIVQTEQTFLRQVTEISIE 679
            :||....|.:.....|:.....:..::||:|.|||... |.|:::.|::.|.:.::..||.:...
Yeast   909 SGFAHQAAKITGLRNYVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDPF 973

  Fly   680 WIKE 683
            |:.|
Yeast   974 WLME 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
PRP16	NP_013012.3	HrpA	319..1071	CDD:224557	268/654 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.710