Protein Alignment ath and PRP43

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_011395.1
• Gene: PRP43 / 852757
• SGDID: S000003088
• Length: 767
• Species: Saccharomyces cerevisiae
• Alignment Length: 657
• Identity: 265/657 - (40%)
• Similarity: 396/657 - (60%)
• Gaps: 38/657 - (5%)

  Fly    55 TSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLL--AGYAKNGMIG 117
            |.|...|.:.::.|||...|...||..:.|..::.:.|||||||||||||:|.  ..:.:|..:.
Yeast    80 TPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLENTQVA 144

  Fly   118 ITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKY 182
            .||||||||::||:|||:|::..:|:.|||::|||:.||..|.::::|||:||||:::|..|.:|
Yeast   145 CTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRY 209

  Fly   183 SVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFN-CKGMYLEG 246
            |.||||||||||:..|:|.|::|...|.|     .:||:::.|||:|.:.|..||| ...:.:.|
Yeast   210 SCIILDEAHERTLATDILMGLLKQVVKRR-----PDLKIIIMSATLDAEKFQRYFNDAPLLAVPG 269

  Fly   247 RTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIR----QLAKI 307
            |||||.:.:|.|...||:.:.:.|:..|| .|.:..|:|:||||::|||...::|.    ||.:.
Yeast   270 RTYPVELYYTPEFQRDYLDSAIRTVLQIH-ATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVRE 333

  Fly   308 DTTGTTDLRVFTLYAQLSQGKQLECFVPTPAN-----VRKVILATNIAETSITIPGIRCVIDCGF 367
            :  |...|.|:.||..|...:|...|.|.|.:     .|||:::|||||||:||.||..|:|.||
Yeast   334 E--GCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGF 396

  Fly   368 VKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYT-KAEMDSFADATQPEILRTN 431
            .|:|.:|....::.|....||||.|.||||||||...|.|:|.|| :|......:.:.|||||:|
Yeast   397 SKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSN 461

  Fly   432 PTSMVLQLLALDI-DCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYPLDP 495
            .:|.||:|..|.| |..:|||:|||..:.:..|.:.|:.|..:  .|:..:|||||...|:||||
Yeast   462 LSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACL--DDEGNLTPLGRLASQFPLDP 524

  Fly   496 KYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGF 560
            ..:.:|:.:..|.|.:|||::|::||..:||:..::..:.|..|...|....|||:|||||::.|
Yeast   525 MLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTKDKKRADDAKNIFAHPDGDHITLLNVYHAF 589

  Fly   561 LKSEKPK----MWCHDNYLNLRSLTYARNVRRQLREISEHLHLALNSSD-----DIEMLKKCILN 616
            ...|..:    .||.|:|||.|||:.|.|:|.||..:....:|.||::|     ..:.::|.:.:
Yeast   590 KSDEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALAS 654

  Fly   617 GFFENIAVLQRDGF--YITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVTEISIE 679
            |||..:| .:|.|.  |||...|....||||:||  .:...::::.|.|.|.:.::|.||.:..|
Yeast   655 GFFMQVA-KKRSGAKGYITVKDNQDVLIHPSTVL--GHDAEWVIYNEFVLTSKNYIRTVTSVRPE 716

  Fly   680 WIKEVVP 686
            |:.|:.|
Yeast   717 WLIEIAP 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	261/643 (41%)
PRP43	NP_011395.1	FlhF	<12..>124	CDD:274609	16/43 (37%)
		HrpA	92..>724	CDD:441249	262/645 (41%)