Protein Alignment ath and YLR419W

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_013523.3
• Gene: YLR419W / 851137
• SGDID: S000004411
• Length: 1435
• Species: Saccharomyces cerevisiae
• Alignment Length: 833
• Identity: 215/833 - (25%)
• Similarity: 354/833 - (42%)
• Gaps: 191/833 - (22%)

  Fly     2 DSKYFATSRNDAVGPSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQK 66
            |||.....||.:.|...:..|..||:.....|     :..::.:::.....:.:|:..|::..::
Yeast   543 DSKGAINKRNISNGKRSINNSSSRKFTKTTIS-----EDTLSVLREEYTKRIKSSEYKSMQLVRE 602

  Fly    67 SLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIG-----ITQPRRVAA 126
            .||.:..:..|:..:..|:.|||..||||||:||:.||:|.....:.|..|     .|||||::|
Yeast   603 QLPAWKKQKVIIDIINKNEVVLITGETGSGKSTQVVQFILDFLQKEKGDFGKTKIVCTQPRRISA 667

  Fly   127 ITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAH 191
            |.:|.||:.|...|.|:.|||.:|..:.|..:|:|:|:|.|||:|.....|.:|:.:::::||.|
Yeast   668 IGLAERVSDERCVTCGEEVGYVIRGVNKTKASTRIKFMTTGVLVRLLQNARTMLENTIVVIDEVH 732

  Fly   192 ERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYF----NCKGMYLEGRTYPV- 251
            ||:::.||:..::|:.     ..::..:|:|:.|||:::|.|..:|    .|   ::||||:|:
Yeast   733 ERSIDTDLIVTLMKNL-----LHRVRGMKIVLMSATVNVDLFKKFFPGLATC---HIEGRTFPIT 789

  Fly   252 -------------RVMHTK----------EEHED----------------------------YIH 265
                         ::...|          |.:.|                            |:|
Yeast   790 DYFLEDILSDLDFKIKREKALSYDDDSVDERNNDDQYLKPRADSKFFTSGQINYDLLCQVVEYVH 854

  Fly   266 TVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQL 330
            ..|       :....|..:::||.|..||......:     .:.:...|..|..|::.|:...|.
Yeast   855 KRL-------KAANDNGSIIVFLPGVGEINKCCNLL-----ANKSNEADFMVLPLHSALTPEDQK 907

  Fly   331 ECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQR 395
            ..|...... |||:::||||||||||......||.|..|...:|..|....|....||||:..||
Yeast   908 RVFKKYHGK-RKVVVSTNIAETSITIDDCVATIDTGRAKSMFYNPKDNTTKLIESFISKAEVKQR 971

  Fly   396 AGRAGRDADGTCYRAYTK--AEMDSFADATQPEILRTNPTSMVLQLLALDI-DCNNF--DFLDPP 455
            .|||||..:|..|:.::|  .|.|..: ...|||.|....|:.|.:.|:.| |...|  ..||.|
Yeast   972 RGRAGRVREGLSYKLFSKNLYENDMIS-MPIPEIKRIPLESLYLSVKAMGIKDVKAFLSTALDAP 1035

  Fly   456 LEDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYP-LDPKYSKLLLTASSFGCMEEILSLVSV 519
            ....|:.|.:.|..:|.:...|.| :|.||:.:...| :|.|:.|||:....|||.:..:.|||:
Yeast  1036 PLPALQKAERILTTIGLVDESDKS-LTQLGQFISLMPVMDSKHGKLLIYGILFGCTDISVLLVSI 1099

  Fly   520 LSSDHV-FVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGFLK---SEKPKMWCHDNYLNLRSL 580
            |....: |:...|..|.......|::|: ||...:|.:...:.|   |...:.:..||.|:...:
Yeast  1100 LGIGVLPFIGGFENREKIKKLLCKYESR-GDLFAVLEIVRDYFKIKDSSIKRKYLRDNLLSYNKI 1163

  Fly   581 TYARNVRRQLREISEHLHLA-----------LNSSD-DIEMLKKCILNGFFENIAVLQ-RDGFYI 632
            ...::...|...|.:.:...           ||.:: :.::|:..:...|:.:||.:| .|..|:
Yeast  1164 NEIKSSTAQYYSILKDVGFLPMDYKVGSISDLNRNERNFDILRAILTGAFYPHIARVQLPDVKYL 1228

  Fly   633 -TASGNI----------------------------------------------RSKIHPSSVLHG 650
             |:||.:                                              |:.|||||||..
Yeast  1229 STSSGAVEKDPEAKMIKYWIRSEEYQDKLEEYKTKISQETQKVDLEDLPLPATRAFIHPSSVLFS 1293

  Fly   651 -----------------------------KYKPSYILFTEIVQTEQTFLRQVT 674
                                         ||  .::|||....|.:.:||.:|
Yeast  1294 TNSVNLEDAKLLSEVDGPISRQSKIPTVVKY--PFVLFTTSQVTNKLYLRDLT 1344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	203/768 (26%)
YLR419W	NP_013523.3	UBA_YLR419W_like	369..409	CDD:270457
		RWD_YLR419W-like	428..532	CDD:467662
		HrpA	600..>1219	CDD:441249	179/642 (28%)
		OB_NTP_bind	1205..>1342	CDD:400182	25/138 (18%)