DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and AT2G47680

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_182290.1	Gene:	AT2G47680 / 819381	AraportID:	AT2G47680	Length:	1015	Species:	Arabidopsis thaliana

Alignment Length:	744	Identity:	197/744 - (26%)
Similarity:	297/744 - (39%)	Gaps:	188/744 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 SLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIGITQPRRVAAITVAR 131
            |||:...:.||:.::..|...||:.|.|.||::|:|||||.|..|.   |..|||||.|.:.||:
plant    25 SLPIMAMKRRIIDKILENRVTLIVGEPGCGKSSQVPQFLLEANMAP---ILCTQPRRFAVVAVAK 86

  Fly   132 RVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRL-LLKYSVIILDEAHERTV 195
            .||:..|..:|..:||.:....:.:..:||.|.|.||||.|.:...| .|||.||||||.|||:|
plant    87 MVAKSRNSDLGGEIGYHIGHSKILTEGSKILFKTAGVLLDEMLDKGLNALKYKVIILDEVHERSV 151

  Fly   196 NADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFNCKG------------------- 241
            .:||:...||     :...|..:|:||:.|||.||..:.:||...|
plant   152 ESDLVLVCVK-----QFLMKNNDLRVVLMSATADITRYRDYFKELGRGERVEVVAIPSPDQRTIF 211

  Fly   242 ----MYLE-----------------GRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPK-NHDV 284
                :|||                 |.:........|.|.::.||.:::   :||...|. ...:
plant   212 QRRVLYLEQVAGLLGVSSDLSAYCPGPSPSSADTEIKPELQNLIHDLIL---YIHEKEPDIEKSI 273

  Fly   285 LIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNI 349
            |:||   ....||.||..||...    .....|..|:..:...:.|.. :....:.|||||||||
plant   274 LVFL---PTYYSLEQQYHQLEPF----FASFEVHILHRSIDTEQALAA-MKICRSRRKVILATNI 330

  Fly   350 AETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKA 414
            ||:|:|||.:..|||.....:..::.....|.::.|.:|::||.||.||.||..||..||....|
plant   331 AESSVTIPKVAYVIDSCRSLQVFWDPSRKRDAVQLVWVSRSQAEQRRGRTGRTCDGEVYRLVPSA 395

  Fly   415 EMDSFADATQPEILRTNPTSMVLQLLALDI----DCNNF--DFLDPPLEDGLRSAYKSLDALGAI 473
            ..:...:...|.||:.:....||.:...:.    |.|..  ..:|||..|.:..|.:.|.::.|:
plant   396 FFNKLEEHEPPSILKLSLRQQVLHICCTESRAINDANALLAKAMDPPDPDVVDDALRMLLSIQAL 460

  Fly   474 KTGDDSYITP--LGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSS-------------- 522
            :........|  .||.:..:||....|.|::.....|.:.:.: |:.||..
plant   461 RKSPRGRYEPTFYGRLLASFPLSFDASILVVKFGEMGMLRQGI-LLGVLMDTLPLPIHHPFGDDS 524

  Fly   523 ------DHVF----VSNSEKNEMAALAH--------AKFQSKHGDHLTLLNVFNGFLKSEK---- 565
                  ||.|    ..:..:.||..:|:        ..|:.||     .|......|..||
plant   525 LFLEYVDHYFGGSKTISGGRREMVLMANFCAFQFWQRVFKDKH-----RLENLKQLLSKEKDKDL 584

  Fly   566 -------PKMWC-----------HDNYLNLRSLTYARNVRRQLREISE----------------- 595
                   .|.||           |.:.|...:|:.....|.|....|:
plant   585 KLMFPEIEKEWCDFHNIAQSSFYHVSELYEDTLSSFHRFRPQFISSSDSQPTYYNPYEFDHTCYI 649

  Fly   596 --------HLHLALNSSDDIE------MLKKCI-----------LNGFFENIAVLQRDGFYITAS 635
                    :||     |:|::      .::||:           .|...||:|.:.::
plant   650 ECQPSEDKYLH-----SEDVDNNQPPPEVRKCVSVPFVPPNAFQANAIAENMASIIKE------- 702

  Fly   636 GNIRSKIHPSSV--LHGKYKP-SYILFTE 661
              ||::..||..  .||..:| .|:.:.|
plant   703 --IRTQCTPSESDNGHGALEPEDYVEYGE 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
AT2G47680	NP_182290.1	DEXDc	33..211	CDD:214692	71/185 (38%)
		DEXDc	43..178	CDD:238005	61/142 (43%)
		Helicase_C	262..382	CDD:278689	42/127 (33%)
		ZnF_C3H1	730..753	CDD:214632	197/744 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810