DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and MEE29

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_181077.3	Gene:	MEE29 / 818101	AraportID:	AT2G35340	Length:	1044	Species:	Arabidopsis thaliana

Alignment Length:	635	Identity:	264/635 - (41%)
Similarity:	402/635 - (63%)	Gaps:	21/635 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 IEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIGITQPRRVA 125
            :::.:|:||::..|.::|..::.:..::|:.||||||||||||:|..|||.|.|.:|.|||||||
plant   397 LQEDRKALPIYTYRDQLLNAVKDHQVLIIVGETGSGKTTQIPQYLHEAGYTKLGKVGCTQPRRVA 461

  Fly   126 AITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEA 190
            |::||.|||||:.|.:|..|||::||||.||..|.::::|||:||||.:.:..|..|||||:|||
plant   462 AMSVAARVAQEMGGKLGHEVGYSIRFEDCTSEKTILKYMTDGMLLRELLGEPDLGSYSVIIVDEA 526

  Fly   191 HERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFNCKGMY-LEGRTYPVRVM 254
            ||||:..|:|||:|||..:.|     .:||::::|||||.:.|.::|:...:: ..||.|||.:.
plant   527 HERTLRTDILFGLVKDIARAR-----PDLKLLISSATMDAEKFSDFFDQAPIFRFPGRRYPVDIC 586

  Fly   255 HTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGT--TDLRV 317
            .|.....||:...:.|:..||...|.. |||:||.||||||::.:.::.  ||...||  .:|.:
plant   587 FTTAPEADYMDAAITTVLTIHVKEPLG-DVLVFLPGQEEIEAVEENLKH--KIRGLGTKIRELII 648

  Fly   318 FTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVL 382
            ..:||.|....|.:.|.|||...|||:|||||||||:||.||:.|:|.||.|.||:|...|::.|
plant   649 CPIYANLPSELQAKIFEPTPEGARKVVLATNIAETSLTIDGIKYVVDPGFSKMKSYNPRTGMESL 713

  Fly   383 KSVRISKAQAWQRAGRAGRDADGTCYRAYTKAE-MDSFADATQPEILRTNPTSMVLQLLALDI-D 445
            ....||||.|.||.|||||.:.|.|||.||... .:...|.|.|||.|||..|:||.|.:|.| :
plant   714 LVTPISKASATQRTGRAGRTSPGKCYRLYTAFNYYNDLEDNTVPEIQRTNLASVVLSLKSLGIHN 778

  Fly   446 CNNFDFLDPPLEDGLRSAYKSLDALGAI-KTGDDSYITPLGRQMVQYPLDPKYSKLLLTASSFGC 509
            ..||||:|||..:.|..:.:.|.||||: :.|:   :|..||:|.::||||..||:::.:..:.|
plant   779 LLNFDFMDPPPSEALIKSLELLFALGALNQLGE---LTKAGRRMAEFPLDPMLSKMIVVSDKYKC 840

  Fly   510 MEEILSLVSVLS-SDHVFVSNSEKNEMAALAHAKFQ-SKHGDHLTLLNVFNGFLKSEKPKMWCHD 572
            .:||:|:.::|| ...:|....:|...|..|...|. ...|||:..|.::|.:.::.....||::
plant   841 SDEIISIAAMLSIGPSIFYRPKDKQVHADNAMKNFHVGNVGDHIAFLKIYNSWKETNYSTQWCYE 905

  Fly   573 NYLNLRSLTYARNVRRQLREISEHLHLALNS-SDDIEMLKKCILNGFFENIAVLQRDGFYITASG 636
            ||:.:||:..||::|.||..:.|.:.:.::| :::::.::|.|:.|||.:.|.||::|.|.|...
plant   906 NYIQVRSMKRARDIRDQLEGLLERVEIDVSSNANELDSIRKSIVAGFFPHTAKLQKNGSYRTVKH 970

  Fly   637 NIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            .....|||:|.| .:..|.::::.::|.|.:.::|||||:..||:.|:.|
plant   971 PQTVHIHPASGL-SQVLPRWVVYHQLVLTSKEYMRQVTELKPEWLIEIAP 1019

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
MEE29	NP_181077.3	DEXDc	399..574	CDD:214692	89/179 (50%)
		DEXDc	421..559	CDD:238005	79/142 (56%)
		Helicase_C	597..732	CDD:278689	64/137 (47%)
		HA2	802..887	CDD:214852	29/87 (33%)
		OB_NTP_bind	911..1021	CDD:285018	37/110 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730