Protein Alignment ath and Dhx40

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_080467.3
• Gene: Dhx40 / 67487
• MGIID: 1914737
• Length: 779
• Species: Mus musculus
• Alignment Length: 686
• Identity: 255/686 - (37%)
• Similarity: 389/686 - (56%)
• Gaps: 59/686 - (8%)

  Fly    51 PILLTSKRTS----IEQQQK-----------SLPVFNCRHRILKELEANDTVLIMSETGSGKTTQ 100
            ||.|..:|.|    .::::|           :.|:...|.::::.:..|..:::...||||||||
Mouse    21 PIELQEERPSAVRIADREEKGCTSQEGGTTPTFPIQKQRKKLIQAVRDNSFLIVTGNTGSGKTTQ 85

  Fly   101 IPQFLLLAGYAKNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLT 165
            :|::|..||::::||||:||||:||||:||:|||:|:..|:|..|||.|||:|.:|:.|.|:::|
Mouse    86 LPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMT 150

  Fly   166 DGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDI 230
            ||.||:..:.|..|.|:||||||||||||:..|:|||::|...:::...:..:|||||.||||::
Mouse   151 DGCLLKHILGDPNLSKFSVIILDEAHERTLTTDILFGLLKKLFQDKSPNRKEHLKVVVMSATMEL 215

  Fly   231 DHFGNYF-NCKGMYLEGRTYPVR------VMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFL 288
            .....:| ||....:.||.||||      :.....|:..||..::.....||...... |:|:||
Mouse   216 AKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAG-DILVFL 279

  Fly   289 TGQEEIESLAQQIRQLAK-----IDTTGTT--DLRVFTLYAQLSQGKQLECFVPTPANVRKVILA 346
            |||.|||...:.:.|:|:     .|...||  .|.:...|..::..:|...|:|.|..:||.:::
Mouse   280 TGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVIS 344

  Fly   347 TNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAY 411
            |||:.||:||.|||.|:|.||||:.:.|...|||:|:.|.|||::|.||:|||||.|.|.|:|.|
Mouse   345 TNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTASGKCFRIY 409

  Fly   412 TKAEMDS-FADATQPEILRTNPTSMVLQLLALDI-DCNNFDFLDPPLEDGLRSAYKSLDALGAI- 473
            :|..... ..|...|||.||:.||:||.|..|.| |...|.:||||.|..:..|.|.|....||
Mouse   410 SKEFWSQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAID 474

  Fly   474 KTGDDSYITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVS--NSEKNEMA 536
            ::|   ::|.||..||::||.|..:..::.|:|..|.:.:|.:.::||.::||:.  :.|..:.|
Mouse   475 RSG---HVTRLGLSMVEFPLPPHLTCAVIRAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEA 536

  Fly   537 ALAHAKFQSKHG---DHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLH 598
            ...|.:..:|.|   |..||..:|.....|..|..||..::::.|.|..|..|..||||:...|.
Mouse   537 EQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLK 601

  Fly   599 LALNSSD---------DIEMLKKCILNGFFENIAVLQRDGFYITASGNIRSK---IHPSSVLH-G 650
               ..||         ..|:|::|:..|:|:|:|.......:.|..|  |..   |||||.|| .
Mouse   602 ---QQSDFPRETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDG--RGSPVHIHPSSALHEQ 661

  Fly   651 KYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            :.|..:|:|.|::.|.:.:.|.|..|..||:::::|
Mouse   662 ETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLP 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	248/653 (38%)
Dhx40	NP_080467.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		6/31 (19%)
		HrpA	51..>699	CDD:441249	249/656 (38%)
		DEAH box	173..176		2/2 (100%)