DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and bgcn

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_523832.2	Gene:	bgcn / 47873	FlyBaseID:	FBgn0004581	Length:	1215	Species:	Drosophila melanogaster

Alignment Length:	800	Identity:	153/800 - (19%)
Similarity:	280/800 - (35%)	Gaps:	239/800 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 EQQQKSLPVF---NCRHRILKELEANDTVLIMSETGSGKTTQIPQFLL--LAGYAKNGMIGITQP 121
            |.|...|..|   :....||:.|.|:..::..:.....|:..:|..:|  ......|..|...:.
  Fly   139 EAQLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKKSNVKIMCIER 203

  Fly   122 RRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVII 186
            :.:.|...::|.|......:|:|||..:.:....|.:|.|.:.|....|| |:..:.....|.::
  Fly   204 QAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLR-SLTSQQFRNISHLV 267

  Fly   187 LDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMD----IDHFG------------- 234
            :::.|......|:|...::.|....:     ||:||:.|...:    .|.||
  Fly   268 VNDVHLHDPYTDILLSEIRMALSSHQ-----NLRVVLLSQMGNPKKFTDFFGEGLQLNMIKQPEV 327

  Fly   235 ----NYFN-------------------------------------CKGMYLEGRT---------- 248
                :|.|                                     |...|.|..|
  Fly   328 APRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELGTDAALRPFLYA 392

  Fly   249 -----YPVRVMHT--------------KEEH---------EDYI--------------------- 264
                 .||...|:              |..|         :.||
  Fly   393 VNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAISLAAMNGNHECI 457

  Fly   265 ----------------------HTVLVTLFHIHRTTPKNH-------DVLIFLTGQEEIESLAQQ 300
                                  :.:::.:.::.||.|:..       ::||.|.....|..|...
  Fly   458 DVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILPTYYHIVKLNYM 522

  Fly   301 IRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAET-SITIPGIRCVID 364
            |  |:...|....:..:|.||..: :...|:..|.......||:|||:|.|: .:.:| .:..||
  Fly   523 I--LSHCLTGSLQECSIFLLYDNM-RNDYLQALVNASDETVKVVLATDIIESLCLKVP-FKYQID 583

  Fly   365 CGFVKEKSFNTV--DGLD----VLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADAT 423
            ........::|.  .|.|    |.|...:.:....|     ....|..|:|..:|...:..::.:
  Fly   584 TACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQ-----PNKGDVQCFRLISKEAYEELSETS 643

  Fly   424 QPEILRT-------------NPTSMVLQLLALDIDCNNFDFLDPPLEDGLRSAYKSLDALGAIKT 475
            ||. |:|             :|.:::.:.|.:.|.       .|||.: :..|.:.|..:..:..
  Fly   644 QPS-LQTMQLDKICLAVKLLSPNTIISEYLGITIS-------PPPLIN-VHHAVQFLKKIDVLDD 699

  Fly   476 GDDSYITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSS------------DH---- 524
            .:|  :|.||.:::..|:..:..::|:......|::.||::||.||:            |:
  Fly   700 AED--VTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIPFTEDIDNLWDR 762

  Fly   525 --VFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGF---LKSEKPKMWCHDNY---LN--LRS 579
              :::.||.|.|...|:..:|    .||...:.::..:   :.:..|.::..|.|   ||  :..
  Fly   763 FTIYIQNSIKKERTYLSDNQF----SDHFIFVRLYKEWQNRMHNRTPPLYLKDEYEFMLNGLMEQ 823

  Fly   580 LTYARN-VRRQLRE---ISEHLHLALNSSDDI----EMLKKCILNGFFENI-AVLQRDGFYITA- 634
            ||..|: :...||.   |.....|::|:.:.:    .|:|..:..|.:.|| ||..|.....:|
  Fly   824 LTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPNIYAVDTRKSSLKSAF 888

  Fly   635 SGNIRSKIHPSSVLHGKYKP 654
            |||:  .:||::||....:|
  Fly   889 SGNV--SMHPNTVLRDFLEP 906

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	4/31 (13%)
		ANK	407..>460	CDD:238125	4/52 (8%)
		Ank_2	413..>460	CDD:289560	4/46 (9%)
		HrpA	<484..973	CDD:224557	99/448 (22%)
		HA2	694..763	CDD:214852	14/70 (20%)
		OB_NTP_bind	823..945	CDD:285018	24/85 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810