DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and l(1)G0007

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster

Alignment Length:	638	Identity:	252/638 - (39%)
Similarity:	391/638 - (61%)	Gaps:	18/638 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 SKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIGITQ 120
            |::.:|.:|::.||||..|..:|..:..|..::|:.|||||||||:.|:|...||:|.||||.||
  Fly   522 SRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIGCTQ 586

  Fly   121 PRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVI 185
            ||||||::||:||:.|::..:|:.|||.:||||.||..|.|:::|||:|||||::|..|..||.|
  Fly   587 PRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAI 651

  Fly   186 ILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYF-NCKGMYLEGRTY 249
            |:||||||:::.|:|||::::....|.     :||::|||||||...|..:| |.....:.|||:
  Fly   652 IMDEAHERSLSTDVLFGLLREIVARRH-----DLKLIVTSATMDSSKFATFFGNVPTFTIPGRTF 711

  Fly   250 PVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQ-LAKIDTTGTT 313
            ||.||.:|...|||:.:.:.....:| .||...|:|||:.|||:||...:.:.: ||:||....
  Fly   712 PVDVMFSKNTCEDYVESAVKQALQVH-LTPNEGDMLIFMPGQEDIEVTCEVLEERLAEIDNAPA- 774

  Fly   314 DLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDG 378
             |.:..:|:||....|.:.|..:...:||.::||||||||:|:.||..|||.|:.|.|.:|...|
  Fly   775 -LSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIG 838

  Fly   379 LDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAE-MDSFADATQPEILRTNPTSMVLQLLAL 442
            :|.|:...||:|.|.||:|||||...|..||.||:.: .|.....|.|||.|||..:.||.|.:|
  Fly   839 MDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSL 903

  Fly   443 D-IDCNNFDFLDPPLEDGLRSAYKSLDALGAI-KTGDDSYITPLGRQMVQYPLDPKYSKLLLTAS 505
            . :|...|.|:|||.:|.:.::...|..|||: .||   .:|.|||||.::||||...::|:.|.
  Fly   904 GVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTG---ALTTLGRQMAEFPLDPPQCQMLIVAC 965

  Fly   506 SFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGFLKSEKPKMWC 570
            ..||..|:|.:||:||...:|.....:.:.|.....|||....||||.|||:..:.::.....||
  Fly   966 RMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWC 1030

  Fly   571 HDNYLNLRSLTYARNVRRQLREISEHLHLALNSSD-DIEMLKKCILNGFFENIAVLQRDGFYITA 634
            ::::::::::...|.||:||::|....:|::.|.. |.::::|||.:.:|...|.|:..|.|:..
  Fly  1031 NEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNL 1095

  Fly   635 SGNIRSKIHPSSVLHG-KYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            ...:...:||:|.|:| ...|.|:::.|::.|.:.:::..|.:...|:.|:.|
  Fly  1096 RTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGP 1148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	94/190 (49%)
		DEXDc	551..689	CDD:238005	75/142 (53%)
		HELICc	722..870	CDD:238034	61/150 (41%)
		HA2	932..1014	CDD:214852	34/84 (40%)
		OB_NTP_bind	1048..1148	CDD:285018	26/99 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468076
Domainoid	1	1.000	98	1.000	Domainoid score	I366
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I130
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13788at6656
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	1	1.000	-	-		otm51353
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.800