Protein Alignment ath and Dhx37

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_001099396.2
• Gene: Dhx37 / 288647
• RGDID: 1306837
• Length: 1150
• Species: Rattus norvegicus
• Alignment Length: 811
• Identity: 236/811 - (29%)
• Similarity: 377/811 - (46%)
• Gaps: 154/811 - (18%)

  Fly    16 PSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKE 80
            |.|...|...:..|.|..|.|.|.          |..:..::...:::::..||:......|::.
  Rat   206 PPPPGTSAPPETPASAPPPALAKP----------AVFIPVNRTPEMQEERLKLPILAEEQAIMEA 260

  Fly    81 LEANDTVLIMSETGSGKTTQIPQFLLLAGY-AKNGMIGITQPRRVAAITVARRVAQELNGTIGDT 144
            :..:..|::..|||||||||:||||..||| :::.:||:|:||||||:.:::|||:|:| .....
  Rat   261 VAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDSIIGVTEPRRVAAVAMSQRVAKEMN-LSHRV 324

  Fly   145 VGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQK 209
            |.|.:|:|...:..|:|:|:||||||:|..||.|||||.|:|:||||||:|..|:|.|::.....
  Rat   325 VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVA 389

  Fly   210 ERRKQKLANLKVVVTSATMDIDHF---GNYFNCKG--MYLEGRTYPVRVMHTKEEH-EDYIHTVL 268
            .|.|:.|. ||:::.|||:.::.|   ...|....  :.:|.|.:||.|...|... :||.....
  Rat   390 LRAKRHLP-LKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRQFPVTVHFNKRTPLDDYSGECF 453

  Fly   269 VTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQL----------------------------- 304
            ..:..|||..|.. .:|:|||||.|:.:|.:::|:.
  Rat   454 RKVCKIHRMLPAG-GILVFLTGQAEVHALCRRLRKAFPIRCSQPQEMEEDSAEGMRRFKKSRTRA 517

  Fly   305 -----------------------------AKID------------------------TTGTTDLR 316
                                         |::|                        ...:..|.
  Rat   518 RKAQAMALPQINLDNYSVLPAGEGDEDREAEMDDEEEALGSDLDLDLGDSEANEGEQPDASLPLH 582

  Fly   317 VFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDV 381
            |..||:.|:..||.:.|.|.|...|..::|||:||||:|||||:.|:|||.||::.::.|.|:..
  Rat   583 VLPLYSLLAPEKQAQVFKPPPEGTRLCVIATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSS 647

  Fly   382 LKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDID- 445
            .:...:|:|.|.||||||||...|.|||.|:.|....|.....|||.|.....::||:.||:|:
  Rat   648 FRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALNIEK 712

  Fly   446 CNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSY-------------ITPLGRQMVQYPLDPKY 497
            ..||.|..||..:.|.:|.:.|.||||::......             ||.|||.|..:|:.|:|
  Rat   713 VINFPFPTPPSVEALIAAEELLIALGALQAPPKQERMKKLQMSQLSCPITALGRTMSTFPVAPRY 777

  Fly   498 SKLLLTASSFGCMEEILSLVSVLSSDHVF-------VSNSEKNEMAALAHAKFQSKH-------- 547
            :|:|..:...||:...:::|:.::...:|       .|..|..|:........|.|.
  Rat   778 AKMLALSQQHGCLPYTIAIVAAMTVRELFEELDRPAASEEELAELKGRRTRVAQMKRTWAGQGAS 842

  Fly   548 ---GDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQL----REISEHLHLALN--- 602
               ||.:.||........:.....:|..|.|..:::...|.:|.||    ..:.....|.|:
  Rat   843 LKLGDLMVLLGAVGACEYAGCSPQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEAGLFLDPKM 907

  Fly   603 ---SSDDIEMLKKCILNGFFENIA--VLQRD-------GFYITASGNIRSKIHPSSVLHGKYKPS 655
               :...:..|::.:..|..:::|  |...|       ..|.|...:....|||||||. :..|.
  Rat   908 QPPTESQVTYLRQIMAAGLGDHLARRVQSEDLLDPKWKNAYKTPLLDDPVFIHPSSVLF-RELPE 971

  Fly   656 YILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            ::::.|||:|.:.:::.|:.:.|:||..::|
  Rat   972 FVVYQEIVETTKMYMKGVSTVEIQWIPSLLP 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	226/758 (30%)
Dhx37	NP_001099396.2	HrpA	248..>1036	CDD:441249	227/759 (30%)