Protein Alignment ath and dhx37

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_593520.1
• Gene: dhx37 / 2543371
• PomBaseID: SPAPB1A10.06C
• Length: 1183
• Species: Schizosaccharomyces pombe
• Alignment Length: 830
• Identity: 256/830 - (30%)
• Similarity: 403/830 - (48%)
• Gaps: 174/830 - (20%)

  Fly     8 TSRNDAVGPSPVKFSFKRKYDAMANSPIL-----EKKPHVA------------------------ 43
            ||.:|:...:..:.|   ::.:.||..||     ||...||
pombe   300 TSEDDSSDDATERAS---RFKSWANKQILGADVGEKSHDVAPDNKIDNPDADMVRAQRMPRKLKM 361

  Fly    44 ---QIKQTIAPILLTSKRTS---------IEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSG 96
               .::.|...|.:..::|:         |::.:.:||:.....||::::.|||.|:|...||||
pombe   362 REEDVEPTADDIEIKGRKTTYTIINRPPEIQESRLALPIVAEEQRIMEQIFANDVVIICGATGSG 426

  Fly    97 KTTQIPQFLLLAGYA-----KNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTS 156
            ||||:||||..||::     ..|||.|||||||||:::|:||::||.| ....|.|.:||:...:
pombe   427 KTTQLPQFLFEAGFSSPESENPGMIAITQPRRVAAVSIAKRVSEELTG-FSSKVSYQIRFDSTIN 490

  Fly   157 RATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRK-----QKL 216
            ..|.|:|:|||:||||...|.||..||.:|:||||||:||.|:|.|::....:.||:     ||:
pombe   491 PDTAIKFMTDGILLRELSSDFLLTAYSAVIVDEAHERSVNTDILLGLLSRIVRLRREMSKSDQKV 555

  Fly   217 ANLKVVVTSATMDIDHFGN---YFNCKG--MYLEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHR 276
            ..||:::.|||:.:..|..   .|:...  :.::.|.|||.:...:....||:......:..||:
pombe   556 KPLKLIIMSATLRVTDFSENKLLFSVPPPIIKIDARQYPVSIHFNRTTKPDYLQDAFDKVCLIHK 620

  Fly   277 TTPKNHDVLIFLTGQEEIESLAQQIRQ-----------------------------------LAK 306
            ..|.. .:|:|||||:|:|.|.|.:|:                                   :.:
pombe   621 RLPAG-SILVFLTGQQEVEQLCQMLRKRFVRSFRPLKSRARIVVSRKTMSVENEDLQSETEDIDQ 684

  Fly   307 IDTTGTTD---------LRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCV 362
            :.|:.::.         :.|..||:.|:...|::.|..:|...|..|:|||:||||||||.||.|
pombe   685 VPTSSSSSVTYDDESEPMYVLPLYSLLTTEDQMKVFDSSPEGHRMCIVATNVAETSITIPNIRYV 749

  Fly   363 IDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMD-SFADATQPE 426
            :|||..||:.:|....:...:...||||.|.||||||||...|.|||.|:.|..| ||...:.||
pombe   750 VDCGKAKERVYNEKTSVQKFEVRWISKANADQRAGRAGRTGPGHCYRLYSSAVFDSSFPLHSLPE 814

  Fly   427 ILRTNPTSMVLQLLALDID-CNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQ 490
            ||||...|:|||:..::|| ..||.|...|....|..:.|.|..||||.:  :..:|.||.||..
pombe   815 ILRTPVESIVLQMKNMNIDNIANFPFPTSPGRSRLEKSLKLLSNLGAIDS--EGVLTKLGEQMSL 877

  Fly   491 YPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVS-----------NSE------------- 531
            :||.|::||:|:.....||:..:::|||.||.:.:|||           ||.
pombe   878 FPLSPRFSKMLIIGQQHGCLPYVIALVSALSINQLFVSKQSLLYDAHDKNSRSEETDLIDDDEIK 942

  Fly   532 -----KNEMAALAHA--KFQSKHGD--HLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVR 587
                 ||.|....:|  :||:...|  .|:||:....:..:...:.:|.:|||..::|....|:|
pombe   943 QKEEYKNRMRGYFNAISRFQAIDPDAPALSLLSAVCAYDYASDKRKFCKENYLREKALEEVTNLR 1007

  Fly   588 RQL---------REISEHLHLALN--SSDDIEMLKKCILNGFFENIAVLQRD--GFYITASGNIR 639
            :|:         |...|...|.|.  :|..|:.|::.|.:.:.:.:|:..::  | |:|
pombe  1008 KQIIGLLKRYMVRVEKEFFKLQLKPPTSVQIKALRQFIASAYIDQVALYDKEKRG-YVT------ 1065

  Fly   640 SKIHPSSVLHGKYKP--------SYILFTEIVQTE--QTFLRQVTEISIE 679
              :.||.....::.|        .|:::..:.::.  :.::..:||||.|
pombe  1066 --LFPSGSEVVQFVPDRTYNIDSEYVVYLSLHESRSGRVYMSPLTEISPE 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	240/730 (33%)
dhx37	NP_593520.1	PTZ00108	<69..314	CDD:240271	3/13 (23%)
		HrpA	397..>909	CDD:441249	195/515 (38%)
		OB_NTP_bind	1041..1121	CDD:400182	15/82 (18%)