Protein Alignment ath and prh1

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_593091.1
• Gene: prh1 / 2541750
• PomBaseID: SPAC2G11.11C
• Length: 719
• Species: Schizosaccharomyces pombe
• Alignment Length: 688
• Identity: 281/688 - (40%)
• Similarity: 403/688 - (58%)
• Gaps: 53/688 - (7%)

  Fly    11 NDAVG---PSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFN 72
            |:.||   .||.|.|        .|||                     |||..|.:|:|:||::.
pombe    65 NEVVGSDNSSPEKRS--------ENSP---------------------SKRKDILEQRKNLPIWE 100

  Fly    73 CRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIGITQPRRVAAITVARRVAQEL 137
            ....:.::::.|..::::.||||||:|||||||....||:.|.:.|||||||||:.:|:|||.|.
pombe   101 AHDTLCQQIQDNRVIVVVGETGSGKSTQIPQFLNECPYAQEGCVAITQPRRVAAVNLAKRVAAEQ 165

  Fly   138 NGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFG 202
            ...:|:.|||::||:|.||:.|:|::||||:||||.|.|.:|.:|..:|||||||||:..|:|.|
pombe   166 GCRLGEQVGYSIRFDDTTSKKTRIKYLTDGMLLRELINDPILSQYHTLILDEAHERTLMTDMLLG 230

  Fly   203 IVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFN----CKGMYLEGRTYPVRVMHTKEEHEDY 263
            .||...|:|     ..|:|::.|||::.:.|..:|:    |   |:.||.|||::.:|.....||
pombe   231 FVKKIIKKR-----PALRVIIMSATLNAERFSEFFDGAEIC---YISGRQYPVQIHYTYTPEPDY 287

  Fly   264 IHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGK 328
            :...|.|:|.:|...|.. |:|:|||||:|||:|...|:..:|...:....::...|:|.|.|.:
pombe   288 LDACLRTIFQLHTKLPPG-DILVFLTGQDEIEALEALIKSYSKQLPSNLPQIQACPLFASLPQEQ 351

  Fly   329 QLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAW 393
            ||:.|:|..||.|||:|:|||||||:||.|||.|||.|..|.|.||:..||:.|....||::.|.
pombe   352 QLQVFLPALANHRKVVLSTNIAETSVTISGIRYVIDTGLAKIKQFNSKLGLESLTVQPISQSAAM 416

  Fly   394 QRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLAL-DIDCNNFDFLDPPLE 457
            ||:|||||:|.|.|||.||:|:.|.....|.|||.|.:.:..||.|.|. ..|..||.::|||.:
pombe   417 QRSGRAGREAAGQCYRIYTEADFDKLPKETIPEIKRIDLSQAVLTLKARGQNDVINFHYMDPPSK 481

  Fly   458 DGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSS 522
            :||..|.:.|.::||:  .|:.:|..||.||...||.|..::.:|.|....|:.|::.:||.||:
pombe   482 EGLLRALEHLYSIGAL--DDNGHINDLGYQMSLIPLLPSLARAVLAAREHNCLSEVIDVVSCLST 544

  Fly   523 DHVFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGFLKS--EKPKMWCHDNYLNLRSLTYARN 585
            |.:|:...||.:.|..|..||....||.||.||....:|:|  :..|.||..|::|.|:|....:
pombe   545 DSMFLFPQEKRDEAIEARLKFLHSEGDLLTCLNALRQYLESSHDSRKQWCSQNFINRRALKTILD 609

  Fly   586 VRRQLREISEHLHLALNSSDDI--EMLKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVL 648
            :|:||||........||||.::  |.|....|:|:..|.|:|..||.|.|..||....|||||.|
pombe   610 IRKQLREHCLKDGWELNSSPEVNSENLLLSFLSGYITNTALLHPDGSYRTIIGNQTISIHPSSSL 674

  Fly   649 HGKYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            .|| |...|::.|:|.|.::::|.|:.|...|:..|.|
pombe   675 FGK-KVEAIMYHELVFTTKSYVRGVSSIRSNWLNAVAP 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	264/627 (42%)
prh1	NP_593091.1	HrpA	95..>719	CDD:441249	265/629 (42%)