Protein Alignment ath and Dhx37

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: XP_017176254.1
• Gene: Dhx37 / 208144
• MGIID: 3028576
• Length: 1161
• Species: Mus musculus
• Alignment Length: 811
• Identity: 239/811 - (29%)
• Similarity: 378/811 - (46%)
• Gaps: 154/811 - (18%)

  Fly    16 PSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKE 80
            |.|...|...|..|.|..|.:.|.          |..:..::...:::::..||:......|::.
Mouse   206 PPPSGISAPPKTPASAPPPPVAKP----------AVFIPVNRTPEMQEERLKLPILAEEQAIMEA 260

  Fly    81 LEANDTVLIMSETGSGKTTQIPQFLLLAGY-AKNGMIGITQPRRVAAITVARRVAQELNGTIGDT 144
            :..:..|::..|||||||||:||||..||| :::.:||:|:||||||:.:::|||:|:| .....
Mouse   261 VAEHPIVIVCGETGSGKTTQVPQFLYEAGYSSEDSIIGVTEPRRVAAVAMSQRVAKEMN-LSHRV 324

  Fly   145 VGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQK 209
            |.|.:|:|...:..|:|:|:||||||:|..||.|||||.|:|:||||||:|..|:|.|::.....
Mouse   325 VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLKYKVVIIDEAHERSVYTDILLGLLSRIVA 389

  Fly   210 ERRKQKLANLKVVVTSATMDIDHF---GNYFNCKG--MYLEGRTYPVRVMHTKEEH-EDYIHTVL 268
            .|.|:.|. ||:::.|||:.::.|   ...|....  :.:|.|.:||.|...|... :||.....
Mouse   390 LRAKRHLP-LKLLIMSATLRVEDFTQNQRLFTTPPPVIKVESRQFPVTVHFNKRTPLDDYSGECF 453

  Fly   269 VTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQL----------------------------- 304
            ..:..|||..|.. .:|:|||||.|:.:|.:::|:.
Mouse   454 RKVCKIHRMLPAG-GILVFLTGQAEVHALCRRLRKAFPFRCSQPQEKEEDSAEGMRRFKKSRTRA 517

  Fly   305 -----------------------------AKID------------------------TTGTTDLR 316
                                         |::|                        ...:..|.
Mouse   518 RKAQAMALPQINLDNYSVLPAGEGDEDREAEMDDEEEALGSDLDLDLGDSEANEGEQPDASLPLH 582

  Fly   317 VFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDV 381
            |..||:.|:..||.:.|.|.|...|..::|||:||||:|||||:.|:|||.||::.::.|.|:..
Mouse   583 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSS 647

  Fly   382 LKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDID- 445
            .:...:|:|.|.||||||||...|.|||.|:.|....|.....|||.|.....::||:.||.|:
Mouse   648 FRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALSIEK 712

  Fly   446 CNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSY-------------ITPLGRQMVQYPLDPKY 497
            ..||.|..||..:.|.:|.:.|.||||::......             ||.|||.|..:|:.|:|
Mouse   713 VINFPFPTPPSVEALVAAEELLVALGALQAPPKQERMKKLQMSQLSCPITALGRTMSTFPVAPRY 777

  Fly   498 SKLLLTASSFGCMEEILSLVSVLSSDHVF-------VSNSE----KNEMAALAHAKF-------Q 544
            :|:|..:...||:...:::|:.::...:|       .|..|    |...|.:|..|.       .
Mouse   778 AKMLALSQQHGCLPYTIAIVAAMTVRELFEELDRPAASEKELAELKGRRARVAQMKRTWAGQGPS 842

  Fly   545 SKHGDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQL----REISEHLHLALN--- 602
            .|.||.:.||........:.....:|..|.|..:::...|.:|.||    ..:.....|.|:
Mouse   843 LKLGDLMVLLGAVGACEYAGCSPQFCQANGLRYKAMLEIRRLRGQLTTAVNAVCPEAGLFLDPKM 907

  Fly   603 ---SSDDIEMLKKCILNGFFENIA--VLQRD-------GFYITASGNIRSKIHPSSVLHGKYKPS 655
               :...:..|::.:..|..:::|  |...|       ..|.|...:....|||||||. |..|.
Mouse   908 QPPTESQVTYLRQIMAAGLGDHLARRVQSEDLLDPKWKNAYKTPLLDDPVFIHPSSVLF-KELPE 971

  Fly   656 YILFTEIVQTEQTFLRQVTEISIEWIKEVVP 686
            ::::.|||:|.:.:::.|:.:.|:||..::|
Mouse   972 FVVYQEIVETTKMYMKGVSTVEIQWIPSLLP 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	229/758 (30%)
Dhx37	XP_017176254.1	HrpA	248..>1036	CDD:441249	230/759 (30%)