Protein Alignment ath and rha-2

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 798
• Identity: 237/798 - (29%)
• Similarity: 366/798 - (45%)
• Gaps: 162/798 - (20%)

  Fly    29 AMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSET 93
            |:..:.::.:|.            ::..:...|::.:..||:|....||::.:..|...::..||
 Worm   209 ALPTTTVINRKK------------VIVERSKEIQKSRAELPIFAEEMRIVEAINENLVTVVCGET 261

  Fly    94 GSGKTTQIPQFLLLAGYAKNG-MIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSR 157
            ||||||||||||..||||..| :||||:|||||||.:|:||..||  ...|.|.|.:|:|...|.
 Worm   262 GSGKTTQIPQFLYEAGYASEGELIGITEPRRVAAIAMAQRVGVEL--AKPDEVSYQIRYEGTRSE 324

  Fly   158 ATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVV 222
            .|.|.|:|||||::|..:|.:|.|||||::||||||::.:|:|.|::......|.| ....|::|
 Worm   325 TTNILFMTDGVLMKEMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSK-TARPLRLV 388

  Fly   223 VTSATMDIDHFGN-----YFNCKGMYLEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNH 282
            :.|||:.:|.|.:     ....|.:.::.|.:||.|...|...:|||.:.......||.|.|..
 Worm   389 IMSATLRLDDFTHKKLFPLLTPKVIKVDARQFPVSVHFEKRTPDDYIASAFRKTCRIHETLPPG- 452

  Fly   283 DVLIFLTGQEEIESLAQQIRQL------------------------------------AKIDTTG 311
            .:|:|:|||.|::.|..::::.                                    .|.:|..
 Worm   453 AILVFVTGQHEVKQLITKLKKRYPVVYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPE 517

  Fly   312 TTD------------------------------------------------------LRVFTLYA 322
            |.|                                                      |....||:
 Worm   518 TEDFEDVDDGLMDGDDMNERGAAEAFDDYEEFENGDGDLSDGKVENSIGAPPADCEPLYCLPLYS 582

  Fly   323 QLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRI 387
            .||.|||...|..|||.:|..:::||:||||:||||::.|||.||.|.:.::::.|:......||
 Worm   583 LLSMGKQRRVFDETPAGMRLCVISTNVAETSLTIPGVKYVIDGGFEKRRLYDSITGVSRFAVCRI 647

  Fly   388 SKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDI-DCNNFDF 451
            |:|...||||||||.:.|..||.|:.|....|.....||||......:||.|.:::| ...||.|
 Worm   648 SQASGDQRAGRAGRISAGHAYRLYSSAVYQDFVKFADPEILSKPADQLVLHLKSMNIVKVVNFPF 712

  Fly   452 LDPPLEDGLRSAYKSLDALGAI----KTG-DDSYITPLGRQMVQYPLDPKYSKLLLTASSFGCME 511
            ...|.|..|.||.|.|..|||:    |.| .::.||.||:.:..:||.|.|:|.:..|.....|.
 Worm   713 PSAPDEQMLESAEKRLCRLGALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMS 777

  Fly   512 EILSLVSVLSSDHVFVSNS--------EKNEMA--ALAHAKFQSKH------GDHLTLLNVFNGF 560
            ..:.|:|:||.....:..|        |..|:.  .|...:....|      ||...|::..:..
 Worm   778 HAILLISLLSVREPLIPVSSLRGDTPEETKELMKNVLKERRRWCSHTGARRLGDLKVLMHAASVA 842

  Fly   561 LKSEKPKMWCHDNYLNLRSLTYARNVRRQLREI------SEHLHLALNS------SDDIEMLKKC 613
            .:.:.....|....|.:::|..||.:|:||..|      .||. .||:|      ....::|::.
 Worm   843 EQIKYNARECEKVGLRVKALVEARKLRQQLTNIVNASCKKEHA-AALDSDLPPPTDQQAQLLRQM 906

  Fly   614 ILNGFFENIA------VLQRD---GFYITA--SGNIRSKIHPSSVLHGKYKPSYILFTEIVQ-TE 666
            ::..|.:.:|      |.|.:   |.|.|.  .|::  .|.|.||:..: :|.::::.|:|| .|
 Worm   907 VVASFSDRLARRVDRSVGQEEVQKGAYETTLIKGHV--FIDPCSVVFTE-EPEFVIYQELVQVNE 968

  Fly   667 QTFLRQVTEISIEWIKEV 684
            :..:..|..:..||:..:
 Worm   969 KKLMTSVCAVDKEWLSRL 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	234/760 (31%)
rha-2	NP_498895.1	HrpA	234..>1020	CDD:441249	234/761 (31%)