Protein Alignment ath and rha-1

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_495890.2
• Gene: rha-1 / 174417
• WormBaseID: WBGene00004355
• Length: 1301
• Species: Caenorhabditis elegans
• Alignment Length: 742
• Identity: 196/742 - (26%)
• Similarity: 323/742 - (43%)
• Gaps: 162/742 - (21%)

  Fly    61 IEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLA------GYAKNGMIGIT 119
            |..|:..|||...|..|::.:..|...||..|||.||:||:.||||.:      |.:.|.:  ::
 Worm   374 ITAQRGELPVAQYRENIVQTVAENRVTLIKGETGCGKSTQVAQFLLESFLENSNGASFNAV--VS 436

  Fly   120 QPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRA-TKIRFLTDGVLLRESIKDRLLLKYS 183
            ||||::||::|.|||.|....:|:|.||.|||:..|.|. ..|.|.|.|||||  :.:..|...|
 Worm   437 QPRRISAISLAERVANERGEEVGETCGYNVRFDSATPRPYGSIMFCTVGVLLR--MMENGLRGIS 499

  Fly   184 VIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFN-------CKG 241
            .:|:||.|||.|:.|.:..::::.....|     :|:||:.|||:|.|.|.|:|:       ...
 Worm   500 HVIIDEIHERDVDTDFVLIVLREMISTYR-----DLRVVLMSATIDTDLFTNFFSSIPDVGPTPV 559

  Fly   242 MYLEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHR------------------------------ 276
            :.:.|||:||:..        |:..:|..|.|:..
 Worm   560 ITMHGRTFPVQSF--------YLEDILHNLQHMPEEPDQKKRKKGGPPPPDDDEGDEEVDDKGRN 616

  Fly   277 ----TTPKNHD----------------------------------VLIFLTGQEEIESLA----- 298
                |.|..::                                  ||:||.|..||.:|.
 Worm   617 MNILTDPSINESLKTAMSRISEKDIPFGVIEAILNDIASRGVDGAVLVFLPGWAEIMTLCNRLLE 681

  Fly   299 -QQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCV 362
             |:..|..|.:        :..|::||:..:|.:.|...|.. ||:|::||||||||||..:..|
 Worm   682 HQEFGQANKYE--------ILPLHSQLTSQEQRKVFNHYPGK-RKIIVSTNIAETSITIDDVVYV 737

  Fly   363 IDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEI 427
            ||....||:.:.:.:.:....:|..||....||.|||||...|..:...:|...::..|....|:
 Worm   738 IDSCKAKERMYTSNNNMVHFATVWASKTNVIQRRGRAGRVRAGYAFHLCSKMRFEALDDHGTAEM 802

  Fly   428 LR--TNPTSMVLQLLALDIDCNNF--DFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPLGRQM 488
            ||  .:..::.::||.|. ....|  ..|.||..|.:..:...|.|:||:....:  :|.||:.:
 Worm   803 LRIPLHQIALTIKLLRLG-SVGEFLGKALQPPPYDMVVESEAVLQAMGALDRNLE--LTSLGKML 864

  Fly   489 VQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQ-SKHGDHLT 552
            .:.|::|..:|:|:..::.|....:..:.|.:|....||...:.:...:....||. :|..||:.
 Worm   865 ARMPIEPVIAKVLILGTALGAGSVMCDVASAMSFPTPFVPREKHHSRLSGTQRKFAGNKFSDHVA 929

  Fly   553 LLNVFNGFLK------SEKPKMWCHDNYLNLRSLTYARNVRRQLREISEH-----------LHLA 600
            :::|..|:.:      |...:.:|....|:...|......||||.::..:           :.:.
 Worm   930 IVSVIQGYREAVQMGASAAEREFCERYSLSNPVLKMTDGARRQLIDVLRNQCSFPEDILFDISVN 994

  Fly   601 LNSSD-DIEMLKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYK----------- 653
            :|..| ::.:::..::...:.|:|       |......:.: |..||.|..||.
 Worm   995 VNGPDRELNLMRSLLVMALYPNVA-------YYVGKRKVLT-IEQSSALINKYSMLVPMNNRQEM 1051

  Fly   654 --PSYIL-FTEIVQTEQTFLRQVTEIS 677
              ||.:| |||.|:|.....:|::.||
 Worm  1052 DFPSPLLVFTEKVRTRCISCKQMSVIS 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	194/736 (26%)
rha-1	NP_495890.2	DSRM_DHX9_rpt1	4..73	CDD:380683
		DSRM_DHX9_rpt2	169..244	CDD:380684
		DEAD-like_helicase_N	325..562	CDD:475120	73/196 (37%)
		HrpA	380..>897	CDD:441249	154/545 (28%)
		OB_NTP_bind	1005..1087	CDD:400182	20/82 (24%)