Protein Alignment ath and let-355

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_491604.3
• Gene: let-355 / 172199
• WormBaseID: WBGene00020263
• Length: 856
• Species: Caenorhabditis elegans
• Alignment Length: 705
• Identity: 258/705 - (36%)
• Similarity: 397/705 - (56%)
• Gaps: 57/705 - (8%)

  Fly    36 LEKKPHVAQIKQTIAPILLTSKRTSIEQ------------QQKSLPVFNCRHRILKELEANDTVL 88
            |.|.|.........|..:.|.|.:|.:|            .:..||:.....:::.||.:.:|::
 Worm   117 LPKTPISTPSNSKNATPMSTRKHSSSQQSPPHFEANYEKFSRPQLPIDAVEQQLMYELASQETLI 181

  Fly    89 IMSETGSGKTTQIPQFLLLAGYAKNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFED 153
            ::.||||||:||:||..:.||.|.:|.|.:|||||||||::|.|||.|:...||..|||.||||:
 Worm   182 VIGETGSGKSTQVPQLCVRAGIANSGSIAVTQPRRVAAISLASRVATEMGTNIGGIVGYHVRFEN 246

  Fly   154 VTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLAN 218
            .|...|||.::|||::||:::...||.|||.:|:||||||::::|:|..|::..|.:||:.. ..
 Worm   247 ATCHKTKIEYMTDGIVLRKALVSPLLDKYSCVIIDEAHERSLHSDVLMCILRQCQDQRRETN-NP 310

  Fly   219 LKVVVTSATMDIDHFGNYF-NCKGMYLEGRTYPVRVMHTKEE------HEDYIHTVLVTLFHIHR 276
            |::::.|||:..:.|.:|| |.|.:.:.|||:|:.|.|...:      ..||::..::.:.::|.
 Worm   311 LRLIIMSATLQAEKFQSYFNNAKVVLVAGRTFPIEVFHVNPKINKSFSSTDYVYNAVICVKYVHL 375

  Fly   277 TTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVR 341
            |.||..|:|:||||.||||::|.|:.:|..........|....|||.|...||.|.|..||...|
 Worm   376 TEPKGRDILVFLTGSEEIEAVASQLAELNGSLPASADVLMPVPLYAALRPEKQKEAFRKTPQGAR 440

  Fly   342 KVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGT 406
            |||::|||||||:||||||.|||.|.||.|.|...:.:||||...:|||||.||||||||||.|.
 Worm   441 KVIISTNIAETSVTIPGIRVVIDSGKVKTKRFEAFNRIDVLKVHNVSKAQAKQRAGRAGRDAPGK 505

  Fly   407 CYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDI-DCNNFDFLDPPLEDGLRSAYKSLDAL 470
            |||.|::.:...|.....|||||.|.::..|:|:.|.: :.:....:|||..|.:.:|...|.:|
 Worm   506 CYRLYSREDFHKFEAENMPEILRCNLSATFLELMKLGMKNPHRLKLIDPPETDNINAALLELTSL 570

  Fly   471 GAIK--TGDDS--YITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVF--VSN 529
            |||:  ..|.|  .:|.:|.....|||.|.::::|..|...||:.|.:.:|:.:.:|.:|  ..:
 Worm   571 GAIRPVNSDRSKFALTEMGDAFCMYPLPPDHARILFQAQKEGCIMEAIKIVAAMQTDALFSGAGD 635

  Fly   530 SEKNEMAALAHAKFQSKHGDHLTLLN---VFNGFL--------------KSEKP---------KM 568
            |:.:........:|:::.|||:|||.   |.|.|.              |:.|.         :.
 Worm   636 SKSDADVDRIRRRFETREGDHITLLKLVLVTNQFFDQLNKKTESDARYGKANKSLEREYNQTIRK 700

  Fly   569 WCHDNYLNLRSLTYARNVRRQLREISEHLHLALNS-SDDIEMLKKCILNGFFENIAVL--QRDGF 630
            :|:||.:|.:.|..|..:..||::|:....:..:: ..|...::|.:..|.|.|....  |.|.:
 Worm   701 FCNDNMINEQHLKTASMIEEQLKQIAIEQKVTFSTCGADFMKMRKALALGMFLNSCEYDRQEDRY 765

  Fly   631 YITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVV 685
            .:..:..|..||||||.| .:.||:||:|:|:::|...|..|||.|..:|::.::
 Worm   766 RLMINPAITLKIHPSSCL-SRSKPAYIVFSELMKTNDLFALQVTLIDGDWVRPLI 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	250/662 (38%)
let-355	NP_491604.3	HrpA	159..>636	CDD:441249	200/477 (42%)
		OB_NTP_bind	743..815	CDD:400182	26/72 (36%)