Protein Alignment ath and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 663
• Identity: 276/663 - (41%)
• Similarity: 414/663 - (62%)
• Gaps: 24/663 - (3%)

  Fly    30 MANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETG 94
            ||.:...:.||.:.:.::         |:.:||:.|||||::..:..::..::|::.::|..|||
Mosquito   218 MAGTKKKDDKPELTEAQR---------KKMTIEETQKSLPIYPFKEDLIAAIQAHNILIIEGETG 273

  Fly    95 SGKTTQIPQFLLLAGYAKNG-MIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRA 158
            |||||||||:|..||:...| .||.||||||||::||.|||:|:...:|:.|||::||||.||..
Mosquito   274 SGKTTQIPQYLYEAGFTNEGKKIGCTQPRRVAAMSVAARVAEEMAVKLGNEVGYSIRFEDCTSER 338

  Fly   159 TKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVV 223
            |.|:::|||.|.||.:.:..|..|:|:|:|||||||::.|:|||:|||..:.|:     :||:::
Mosquito   339 TVIKYMTDGTLHREFLSEPDLASYAVMIIDEAHERTLHTDILFGLVKDIARFRK-----DLKLLI 398

  Fly   224 TSATMDIDHFGNYFNCKGMY-LEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIF 287
            :|||:|.:.|.::|:...:: :.||.|||.:.:||....|||...:|::..||.|.|.. |:|:|
Mosquito   399 SSATLDAEKFSDFFDKAPIFRIPGRRYPVDIFYTKAPEADYIDACVVSVLQIHATQPLG-DILVF 462

  Fly   288 LTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAET 352
            ||||||||:..:.::...|...:...:|.:..:||.|....|.:.|.|||.|.||||||||||||
Mosquito   463 LTGQEEIEACQEMLQDRVKRLGSKLKELLILPIYANLPSDMQAKIFEPTPPNARKVILATNIAET 527

  Fly   353 SITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTK-AEM 416
            |:||..|..|||.||.|:.:||:..|::.|..|.||||.|.||||||||.|.|.|:|.||. |..
Mosquito   528 SLTIDNIIYVIDPGFAKQNNFNSRTGMETLLVVPISKASANQRAGRAGRVAPGKCFRLYTAWAYN 592

  Fly   417 DSFADATQPEILRTNPTSMVLQLLALDI-DCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSY 480
            :...|.|.|||.|.|..:.||.|..|.| |..:|||||||....|..|.:.|.||||:....:
Mosquito   593 NELEDNTVPEIQRINLGNAVLMLKTLGIHDLLHFDFLDPPPHQTLILALEQLYALGALNHHGE-- 655

  Fly   481 ITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLS-SDHVFVSNSEKNEMAALAHAKFQ 544
            :|.|||:|.::|:||..:|:||.:..:.|.|||:|:.::|| :..:|....:|...|..|...|.
Mosquito   656 LTKLGRRMAEFPVDPMMAKMLLASEKYKCSEEIVSIAAMLSVNGAIFYRPKDKIIHADTARKNFN 720

  Fly   545 SKHGDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHLALNSSD-DIE 608
            .:|||||:|:.|:|.:::|:....||::|::..||:..||:||.||..:.:.:.:.:.|.: |..
Mosquito   721 HRHGDHLSLMQVYNQWVESDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIEMVSGESDTT 785

  Fly   609 MLKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQV 673
            .::|.|..|:|.::|.|.:.|.|.|...|....|||:|.|. :..|.::|:.|:|.|.:.|:|.|
Mosquito   786 NVRKAITAGYFYHVARLSKSGNYKTVKHNQDVMIHPNSALF-EDLPRWLLYHELVFTTKEFMRSV 849

  Fly   674 TEISIEWIKEVVP 686
            .||..:|:.||.|
Mosquito   850 IEIESKWLLEVAP 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ath	NP_609356.2	HrpA	67..>686	CDD:441249	266/624 (43%)
l(2)37Cb	XP_319843.5	None