DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4901 and dqx1

DIOPT Version :9

Sequence 1:	NP_001334733.1	Gene:	CG4901 / 34357	FlyBaseID:	FBgn0032194	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	XP_021332040.1	Gene:	dqx1 / 100002601	ZFINID:	ZDB-GENE-150224-1	Length:	571	Species:	Danio rerio

Alignment Length:	726	Identity:	169/726 - (23%)
Similarity:	289/726 - (39%)	Gaps:	233/726 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GPSPVKFSFKRKYDAMANSPI---------------------LEKKPHVAQIKQTIAPILLTSKR 58
            |||  .||...|..|:.|..|                     ||..|:..        :..:|:.
Zfish    11 GPS--AFSMSSKASALDNLSISSLISGDLEEDGEPLDDDLADLEVNPYDG--------LPFSSRY 65

  Fly    59 TSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKN-----GMIGI 118
            .|:.:|:|.|||::.:..:|:.:|.:..:::.|:.|:||:||:||:.:  .||::     |::.:
Zfish    66 YSLLEQRKQLPVWSLKLSLLEHMEKHSMIILSSDGGTGKSTQVPQWCV--EYAQSHEFSQGVVCV 128

  Fly   119 TQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYS 183
            |||...||.::|.|.|.|::.::|..|||.|..||..:..|.:||:||.:||:|.:.|.||.:|.
Zfish   129 TQPYSAAACSLALRAADEMDLSLGLEVGYRVPHEDGCTPDTILRFVTDALLLQEMMSDPLLRQYG 193

  Fly   184 VIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFNCKGMYLEGRT 248
            |:::|||.||||..|:|.|:::|..::|     |:|:|:|.:|......|.::.        |.|
Zfish   194 VLVIDEAQERTVATDVLLGLLRDVCRQR-----ADLRVLVLTAPAAATSFSSFL--------GET 245

  Fly   249 YP------VRVMHTKEEH------EDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQI 301
            .|      ....||:..:      .|.:...:.|:..:||..... |:|:||.|.:||...|..:
Zfish   246 VPHLQLPCAPQTHTEVLYREPAAGRDLLTAAVHTILDLHRRGEPG-DMLVFLPGPQEISECASAL 309

  Fly   302 RQLAKIDTTGTTDLRVFTLYA------------QLSQGKQLECFVPTPANVRKVILATNIAETSI 354
            .:.....:...:.|||..::|            :...|.:||   |.....|:|:|....||.|.
Zfish   310 EKECVSLSAQLSCLRVVCVHAGAGGSSAQLYDTEAPDGGELE---PAEDPRRRVVLTDACAEASF 371

  Fly   355 TIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSF 419
            :|..:|.|||||.             .:|:|.:...               .|..|.:.
Zfish   372 SINNVRYVIDCGV-------------QIKTVCVCVC---------------VCVCAVSA------ 402

  Fly   420 ADATQPEILRTNPTSMVLQLLALDIDCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPL 484
                                              ||                       .::||
Zfish   403 ----------------------------------PP-----------------------CFVTP- 409

  Fly   485 GRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGD 549
                   |.|                                     |.|.||..........||
Zfish   410 -------PAD-------------------------------------KVEAAATHRRTMLHPDGD 430

  Fly   550 HLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHL-----ALNSSDDIEM 609
            |:||:|::|.:|:..:.:.||..|:|:..:|..|..:|.:|.|:.:.:.|     |....|:...
Zfish   431 HMTLINIYNAYLQHNEDEAWCRTNFLSSSALRLAVVIRAELLEVMQRIELPVSPPAFGCQDNSTN 495

  Fly   610 LKKCILNGFFENIA-VLQRDGFYITASGNIRSKIHPSSVLHGKYK--------PSYILFTEIVQT 665
            :|:.:::|||..:| .:...|.|:..:....|::||.|    .|:        ||::|:.:...:
Zfish   496 IKRALISGFFLKVAHDVDGSGNYLLLTHRHVSQLHPFS----SYRCRRPQLSPPSWVLYHDFTVS 556

  Fly   666 EQTFLRQVTEI 676
            ....:..|:||
Zfish   557 HDNCICIVSEI 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4901	NP_001334733.1	None
dqx1	XP_021332040.1	HA2	47..>385	CDD:331981	108/377 (29%)
dqx1	XP_021332040.1	OB_NTP_bind	469..570	CDD:311586	23/103 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920