DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5731 and naga

DIOPT Version :9

Sequence 1:	NP_609354.1	Gene:	CG5731 / 34355	FlyBaseID:	FBgn0032192	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001032465.2	Gene:	naga / 560778	ZFINID:	ZDB-GENE-051113-256	Length:	437	Species:	Danio rerio

Alignment Length:	406	Identity:	205/406 - (50%)
Similarity:	265/406 - (65%)	Gaps:	17/406 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LW----IILLSSTFGKCLDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVAD 65
            :|    :.|..|:....|||||.:|||||||:||||||:.||.|||.||||||||..|.|.:..|
Zfish     1 MWSACVLFLAFSSAALALDNGLMRTPPMGWLAWERFRCDIDCQNDPYNCISEQLFMDMADRLSED 65

  Fly    66 GYASVGYEYINIDDCWLEKHRSHDGKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAG 130
            |:..:||.|:||||||..|.|...|:|..|.||||.||..|:.|:|.||||.|||.|.|..||.|
Zfish    66 GWKELGYVYVNIDDCWSSKDRDAQGRLQPDPKRFPRGIPHLAQYVHDRGLKLGIYGDMGTLTCGG 130

  Fly   131 YPG-IIGYEEKDALQFADWNVDYVKLDGCYALPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQI 194
            ||| .:...|.||..||||.:|.:||||||:.....:.||....:.||:||:.:.||||||.||
Zfish   131 YPGTTLDKIETDAQTFADWGIDMLKLDGCYSNSSYQEQGYPMMSKALNATGRPIGYSCSWPAYQ- 194

  Fly   195 YAGIQP--NYSAIQTHCNLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIG 257
             .|:.|  ||:.:...||||||||||||||.||..|:|::.:|||.:.|.|.||.||||||||||
Zfish   195 -GGLPPKVNYTLLGQICNLWRNYDDIQDSWDSVMGIVDWFFDNQDALQPAAAPGQWNDPDMLIIG 258

  Fly   258 NFGLSYEQAKTQFAIWSILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHK- 321
            :|.||.:|::.|.|:|||:||||.||.|||||....:.:|||:.:|:::||||||||||:.|.|
Zfish   259 DFSLSLDQSRAQMALWSIMAAPLFMSNDLRTISSAARSVLQNKAVISINQDPLGIQGRRLLKEKS 323

  Fly   322 GIEIWSRPIGPLYQNFYSYAIAFVNRRTDGTPSDISVTLKELGLINFSGYRVEDLYENVDYGVLY 386
            ||:::.||:..     .:.|:.|.:||:| .|...:.:||.|| .....:.|.|::.......|.
Zfish   324 GIQVFQRPLSK-----GASALVFFSRRSD-MPYRYTTSLKTLG-YQPGVFEVFDVFSEQRLPELK 381

  Fly   387 PNTKIKVKVNPSGVVM 402
            .:|:..|.:|||||||
Zfish   382 DSTQFTVSINPSGVVM 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5731	NP_609354.1	AmyAc_family	25..399	CDD:298606	192/377 (51%)
naga	NP_001032465.2	AmyAc_family	25..394	CDD:324178	192/377 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596762
Domainoid	1	1.000	43	1.000	Domainoid score	I12415
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H221
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1855
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	1	1.000	-	-		otm26344
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	O	PTHR11452
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X887
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910