DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5731 and CG7997

DIOPT Version :9

Sequence 1:	NP_609354.1	Gene:	CG5731 / 34355	FlyBaseID:	FBgn0032192	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_611119.1	Gene:	CG7997 / 36829	FlyBaseID:	FBgn0034117	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	403	Identity:	244/403 - (60%)
Similarity:	303/403 - (75%)	Gaps:	5/403 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LWIILLSSTFGKCLDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVADGYAS 69
            |.:.:|..:.|  ||||||..|||||:|||||||.|||...||.||||:|||...|::|::|||.
  Fly    13 LLLQVLQLSMG--LDNGLALKPPMGWMSWERFRCITDCKLYPDECISEKLFQRHADLLVSEGYAD 75

  Fly    70 VGYEYINIDDCWLEKHRSHD-GKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAGYPG 133
            .||||:.||||||||:|.:| .|||.||||||||:.||||:||::|||||:|:|||..|||||||
  Fly    76 AGYEYVIIDDCWLEKNRDNDTQKLVPDRKRFPNGLNALSDHIHNQGLKFGLYQDYGTNTCAGYPG 140

  Fly   134 IIGYEEKDALQFADWNVDYVKLDGCYALPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQIYAGI 198
            :|.:.:.||..||||:|||||||||||...||..||..||||||.||:.||||||||.||..||.
  Fly   141 VIKHMKLDAQTFADWDVDYVKLDGCYANISDMASGYPEFGRLLNETGRPMVYSCSWPAYQEDAGE 205

  Fly   199 QPNYSAIQTHCNLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIGNFGLSY 263
            .|:|.:::.|||||||:|||:||..|:..||||:..|||.|.|:.|||||||||||::||:||||
  Fly   206 MPDYESLKQHCNLWRNWDDIEDSLESLMQIIDYFAKNQDRIQPHGGPGHWNDPDMLLLGNYGLSY 270

  Fly   264 EQAKTQFAIWSILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHKGIEIWSR 328
            :|:|.|.|||:|:||||:||.||..:||:.|.|||||.:||||||.|||||||:.....||:|.|
  Fly   271 DQSKLQMAIWAIMAAPLIMSNDLAAVRPEIKAILQNRAVIAVDQDELGIQGRRVLSRNQIEVWKR 335

  Fly   329 PIGPLYQN-FYSYAIAFVNRRTDGTPSDISVTLKELGLINFSGYRVEDLYE-NVDYGVLYPNTKI 391
            ||.|:.:: .:|||:|||:||.||.|..|..|:|||||.|..||.|:|||: :...||....::.
  Fly   336 PITPVTKSGHHSYAVAFVSRRDDGAPYRIPFTVKELGLTNPKGYNVQDLYDASSKLGVFQSESQF 400

  Fly   392 KVKVNPSGVVMLK 404
            ..:|||:||...|
  Fly   401 ITRVNPNGVTFYK 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5731	NP_609354.1	AmyAc_family	25..399	CDD:298606	232/376 (62%)
CG7997	NP_611119.1	AmyAc_family	31..408	CDD:298606	232/376 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473073
Domainoid	1	1.000	233	1.000	Domainoid score	I636
eggNOG	1	0.900	-	-		E1_KOG2366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	269	1.000	Inparanoid score	I923
Isobase	1	0.950	-	0.930827	Normalized mean entropy	S1639
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	1	1.000	-	-		otm26344
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	P	PTHR11452
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R31
SonicParanoid	1	1.000	-	-		X887
	14	13.790