DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5731 and Gla

DIOPT Version :9

Sequence 1:	NP_609354.1	Gene:	CG5731 / 34355	FlyBaseID:	FBgn0032192	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001102290.2	Gene:	Gla / 363494	RGDID:	1589721	Length:	421	Species:	Rattus norvegicus

Alignment Length:	410	Identity:	198/410 - (48%)
Similarity:	264/410 - (64%)	Gaps:	12/410 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LATLWIILLSSTFGKCLDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVADG 66
            |..|.::..|....:.||||||:||.||||.||||.||.||..:||.|||||||..|.:::|:||
  Rat    18 LRPLALVFWSILGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDACISEQLFMQMAELMVSDG 82

  Fly    67 YASVGYEYINIDDCWLEKHRSHDGKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAGY 131
            :...||||:.|||||:...|...|:|.||.||||:|||.|::|:||:|||.|||.|.|..||||:
  Rat    83 WRDAGYEYLCIDDCWMAPERDSKGRLQADPKRFPSGIKHLANYVHSKGLKLGIYADVGKKTCAGF 147

  Fly   132 PGIIGYEEKDALQFADWNVDYVKLDGCYA-LPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQIY 195
            ||..|..:.||..||||.:|.:|.|||:. ....:.:||......||.||:|:||||.||:| :.
  Rat   148 PGSFGSYDIDAQTFADWGIDLLKFDGCHCDSVVSLANGYKYMSLALNRTGRSIVYSCEWPLY-LR 211

  Fly   196 AGIQPNYSAIQTHCNLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIGNFG 260
            ...:|||:.||.:||.|||:||:.|||.|:::|:.:...:|..|...||||.|||||||:|||||
  Rat   212 PFHKPNYTDIQYYCNHWRNFDDVYDSWESIKSILAWTVTHQKDIVEVAGPGGWNDPDMLVIGNFG 276

  Fly   261 LSYEQAKTQFAIWSILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHKGIEI 325
            ||::|..||.|:|:|:|||||||.|||.|..|.|.:|||..:||::|||||.||....|...||:
  Rat   277 LSWDQQVTQMALWAIMAAPLLMSNDLRQISSQAKALLQNEDVIAINQDPLGKQGYCFRKENEIEV 341

  Fly   326 WSRPIGPLYQNFYSYAIAFVNRRTDGTPSDISVTLKELG---LINFSGYRVEDLYENVDYGVL-Y 386
            |.||:..|     ::|:|..|.:..|.|...::.:..||   ..|......:.|.|.|..|.. :
  Rat   342 WERPLSNL-----AWAVAVRNLQEIGGPRFYTIQISSLGRGLACNPGCIITQILPEKVHLGFYEW 401

  Fly   387 PNTKIKVKVNPSGVVMLKGE 406
            |.| :|.::||||.|:|:.|
  Rat   402 PLT-LKTRINPSGTVLLRLE 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5731	NP_609354.1	AmyAc_family	25..399	CDD:298606	184/378 (49%)
Gla	NP_001102290.2	Melibiase_2	41..413	CDD:293108	184/378 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2366
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	O	PTHR11452
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X887
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.720