DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5731 and Gla

DIOPT Version :9

Sequence 1:	NP_609354.1	Gene:	CG5731 / 34355	FlyBaseID:	FBgn0032192	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_038491.2	Gene:	Gla / 11605	MGIID:	1347344	Length:	421	Species:	Mus musculus

Alignment Length:	409	Identity:	198/409 - (48%)
Similarity:	263/409 - (64%)	Gaps:	10/409 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LATLWIILLSSTFGKCLDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVADG 66
            |..|.::..|....:.||||||:||.||||.||||.||.||..:||.|||||||..|.:::|:||
Mouse    18 LCPLALVFWSILGVRALDNGLARTPTMGWLHWERFMCNLDCQEEPDACISEQLFMQMAELMVSDG 82

  Fly    67 YASVGYEYINIDDCWLEKHRSHDGKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAGY 131
            :...||:|:.|||||:...|...|:|.||.:|||:|||.|::|:||:|||.|||.|.||.||||:
Mouse    83 WRDAGYDYLCIDDCWMAPERDSKGRLQADPQRFPSGIKHLANYVHSKGLKLGIYADVGNKTCAGF 147

  Fly   132 PGIIGYEEKDALQFADWNVDYVKLDGCYA-LPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQIY 195
            ||..|..:.||..||||.||.:|.|||:. ....:::||......||.||:|:||||.||:| :.
Mouse   148 PGSFGSYDIDAQTFADWGVDLLKFDGCHCDSVVSLENGYKYMALALNRTGRSIVYSCEWPLY-LR 211

  Fly   196 AGIQPNYSAIQTHCNLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIGNFG 260
            ...:|||:.||.:||.|||:||:.|||.|::||:.:....|..|...||||.|||||||:|||||
Mouse   212 PFHKPNYTDIQYYCNHWRNFDDVYDSWESIKNILSWTVVYQKEIVEVAGPGSWNDPDMLVIGNFG 276

  Fly   261 LSYEQAKTQFAIWSILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHKGIEI 325
            ||::|..||.|:|:|:|||||||.|||.|..|.|.:|||:.:||::|||||.||....|...||:
Mouse   277 LSWDQQVTQMALWAIMAAPLLMSNDLRQISSQAKALLQNKDVIAINQDPLGKQGYCFRKENHIEV 341

  Fly   326 WSRPIGPLYQNFYSYAIAFVNRRTDGTPSDISVTLKEL--GLINFSGYRVEDLY-ENVDYGVLYP 387
            |.||:..|     ::|:|..|.:..|.|...::.:..|  ||....|..:..|. |.|..|....
Mouse   342 WERPLSNL-----AWAVAVRNLQEIGGPCPYTIQISSLGRGLACNPGCIITQLLPEKVHLGFYEW 401

  Fly   388 NTKIKVKVNPSGVVMLKGE 406
            ...:|.:|||||.|:.:.|
Mouse   402 TLTLKTRVNPSGTVLFRLE 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5731	NP_609354.1	AmyAc_family	25..399	CDD:298606	185/377 (49%)
Gla	NP_038491.2	Melibiase_2	41..413	CDD:293108	185/377 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850749
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	O	PTHR11452
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R31
SonicParanoid	1	1.000	-	-		X887
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.890