DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL7 and RPL7A

DIOPT Version :9

Sequence 1:	NP_001285794.1	Gene:	RpL7 / 34352	FlyBaseID:	FBgn0005593	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_011439.1	Gene:	RPL7A / 852804	SGDID:	S000003044	Length:	244	Species:	Saccharomyces cerevisiae

Alignment Length:	251	Identity:	126/251 - (50%)
Similarity:	176/251 - (70%)	Gaps:	18/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AAKKLPAVPESKLKFSKKQISKRVAE---SKRRLKKAAVIALRKKEN----LVRAEKYQNEYIKA 67
            ||:|: ..|||:||.||.|  ::.||   ::|..:|||     .||.    |.|...||.||..|
Yeast     2 AAEKI-LTPESQLKKSKAQ--QKTAEQVAAERAARKAA-----NKEKRAIILERNAAYQKEYETA 58

  Fly    68 EQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKAT 132
            |:..|:.:|.||....:||.|:.||.|||||:||||:.||.||||||.||.:||:|.|:|:.|||
Yeast    59 ERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKAT 123

  Fly   133 INMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHE 197
            :.:|::.|||:.:|||:..::|:|:|||||.|.|:||||::||.:||..|.: :.|..::||:||
Yeast   124 LELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGK-YGILSIDDLIHE 187

  Fly   198 IFTVGPNFKYASNFLWPFKLNTPTGGW--RKKANHYVNGGDFGNREDQINRLLRKM 251
            |.||||:||.|:||||||||:.|:|||  .:|..|::.||.|||||:.||:|::.|
Yeast   188 IITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSM 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL7	NP_001285794.1	uL30_euk	19..252	CDD:273548	122/242 (50%)
		Ribosomal_L30_N	20..90	CDD:285340	29/76 (38%)
		Ribosomal_L7_archeal_euk	92..252	CDD:100099	91/162 (56%)
RPL7A	NP_011439.1	uL30_euk	10..244	CDD:273548	122/242 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344205
Domainoid	1	1.000	133	1.000	Domainoid score	I1108
eggNOG	1	0.900	-	-		E1_COG1841
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H87772
Inparanoid	1	1.050	238	1.000	Inparanoid score	I700
Isobase	1	0.950	-	0	Normalized mean entropy	S407
OMA	1	1.010	-	-		QHG53947
OrthoFinder	1	1.000	-	-		FOG0001677
OrthoInspector	1	1.000	-	-		otm46661
orthoMCL	1	0.900	-	-		OOG6_100755
Panther	1	1.100	-	-	LDO	PTHR11524
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1144
SonicParanoid	1	1.000	-	-		X1237
TreeFam	1	0.960	-	-
	16	15.740