DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL7 and RPL7

DIOPT Version :9

Sequence 1:	NP_001285794.1	Gene:	RpL7 / 34352	FlyBaseID:	FBgn0005593	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_000962.2	Gene:	RPL7 / 6129	HGNCID:	10363	Length:	248	Species:	Homo sapiens

Alignment Length:	243	Identity:	145/243 - (59%)
Similarity:	183/243 - (75%)	Gaps:	7/243 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRK-KENLV--RAEKYQNEYIKAEQREIK 73
            |::|||||:   ..||:.:....:.||..||.|...||| :..|:  :|:.|..||.:..:.||:
Human     9 KEVPAVPET---LKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIR 70

  Fly    74 LRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRI 138
            :.|:|:|...||||||.|||||:||||||.|:|||||||||.|||||.||.|:|||||:||||||
Human    71 MARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRI 135

  Fly   139 AEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGP 203
            .||||.|||||||||.|||||||:.|.|::|:.:|||.:|.|.|.: :.|.|:|||:|||:|||.
Human   136 VEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGK-YGIICMEDLIHEIYTVGK 199

  Fly   204 NFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKM 251
            .||.|:||||||||::|.||.:||..|:|.|||.||||||||||:|:|
Human   200 RFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRM 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL7	NP_001285794.1	uL30_euk	19..252	CDD:273548	140/236 (59%)
		Ribosomal_L30_N	20..90	CDD:285340	25/72 (35%)
		Ribosomal_L7_archeal_euk	92..252	CDD:100099	112/160 (70%)
RPL7	NP_000962.2	4 X 12 AA tandem repeats	7..54		17/47 (36%)
RPL7	NP_000962.2	uL30_euk	16..248	CDD:273548	140/236 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148531
Domainoid	1	1.000	151	1.000	Domainoid score	I4376
eggNOG	1	0.900	-	-		E1_COG1841
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H87772
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2929
Isobase	1	0.950	-	0	Normalized mean entropy	S407
OMA	1	1.010	-	-		QHG53947
OrthoDB	1	1.010	-	-		D1544778at2759
OrthoFinder	1	1.000	-	-		FOG0001677
OrthoInspector	1	1.000	-	-		oto89146
orthoMCL	1	0.900	-	-		OOG6_100755
Panther	1	1.100	-	-	LDO	PTHR11524
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1237
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720