DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL7 and NPSR1

DIOPT Version :9

Sequence 1:	NP_001285794.1	Gene:	RpL7 / 34352	FlyBaseID:	FBgn0005593	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001287864.1	Gene:	NPSR1 / 387129	HGNCID:	23631	Length:	390	Species:	Homo sapiens

Alignment Length:	136	Identity:	22/136 - (16%)
Similarity:	44/136 - (32%)	Gaps:	50/136 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 NNGVFIKLNKATINMLRIA-----------EPYITW----GYPNLKSVRELIYKRGFVKHNRQRV 170
            |.|:   ::||.|..::.:           .||..:    .:..|...:|..|....:    |.:
Human   261 NRGL---ISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVII----QNL 318

  Fly   171 PITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASN-----------FLWPFKLNT---PT 221
            |..::              .:..|::.:|:...:|...:|           .||...|.:   ..
Human   319 PALNS--------------AINPLIYCVFSSSISFPCRANSSVYLLACDVSVLWALVLTSEKESC 369

  Fly   222 GGWRKK 227
            ..||:|
Human   370 ESWRRK 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL7	NP_001285794.1	uL30_euk	19..252	CDD:273548	22/136 (16%)
		Ribosomal_L30_N	20..90	CDD:285340
		Ribosomal_L7_archeal_euk	92..252	CDD:100099	22/136 (16%)
NPSR1	NP_001287864.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
NPSR1	NP_001287864.1	7tm_1	66..330	CDD:278431	13/89 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1841
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900