Protein Alignment Ripalpha and RPAIN

DIOPT Version :9

• Sequence 1: NP_609351.1
• Gene: Ripalpha / 34351
• FlyBaseID: FBgn0032189
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_001153715.1
• Gene: RPAIN / 84268
• HGNCID: 28641
• Length: 231
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 46/198 - (23%)
• Similarity: 84/198 - (42%)
• Gaps: 41/198 - (20%)

  Fly    23 AKRQRMGNQMPRLREMLREKYRK-----------------------RIIETRNRCTDAQREIQLS 64
            |.|||...:|...|:.|..:||:                       ..:::...|.:     .|:
Human    24 AFRQRCLERMRNSRDRLLNRYRQAGSSGPGNSQNSFLVQEVMEEEWNALQSVENCPE-----DLA 83

  Fly    65 ELREILRLE-LSELEKDVELEELILEE--LLSDVNEWYALGEKNLETLYAEPDEQQKEVLCPVCQ 126
            :|.|::.:. |.|::     :|||.:|  ::|:..:.....||.|..:.||  .:...::||||.
Human    84 QLEELIDMAVLEEIQ-----QELINQEQSIISEYEKSLQFDEKCLSIMLAE--WEANPLICPVCT 141

  Fly   127 IKNLRHHKGAFICECGIRF-EHSANM--EQLQILLQQQIASHELQCTQALRFFIEPASGQLYDMC 188
            ..|||...|..:|:||:.. .||:.:  ::|:..|:..|..|...|.....|.:...:.:...:.
Human   142 KYNLRITSGVVVCQCGLSIPSHSSELTEQKLRACLEGSINEHSAHCPHTPEFSVTGGTEEKSSLL 206

  Fly   189 GSC 191
            .||
Human   207 MSC 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ripalpha	NP_609351.1	RPA_interact_C	122..196	CDD:291434	21/73 (29%)
RPAIN	NP_001153715.1	RPA_interact_N	8..46	CDD:291432	8/21 (38%)
		RPA_interact_M	60..124	CDD:291433	13/73 (18%)
		RPA_interact_C	137..211	CDD:291434	21/73 (29%)
		Mediates nuclear export	164..180		3/15 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1518754at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106367
Panther	1	1.100	-	-	LDO	PTHR31742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.810