Protein Alignment Ripalpha and Rpain

DIOPT Version :10

• Sequence 1: NP_609351.1
• Gene: Ripalpha / 34351
• FlyBaseID: FBgn0032189
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_081462.1
• Gene: Rpain / 69723
• MGIID: 1916973
• Length: 219
• Species: Mus musculus
• Alignment Length: 238
• Identity: 51/238 - (21%)
• Similarity: 98/238 - (41%)
• Gaps: 66/238 - (27%)

  Fly     3 STQSPVYRTSVEQ--KRHAQEVAKR---QRMGNQMPRL---------------------REMLRE 41
            |:.|| :|...:|  ..|.:|..::   :||.|...||                     :|::.|
Mouse     4 SSGSP-HRLLYKQVGSPHWKETFRQGCLERMRNSRHRLLNKYRQAAGSTPGTASDRLLVQEVMEE 67

  Fly    42 KYRKRIIETRNRCTDAQREIQLS-ELREILRLE----------LSELEKDVELEELILEELLSDV 95
            ::..  :::...|.:|..:::|. :|..:..:|          :||.|:|:|.:|..|..:|:
Mouse    68 EWAS--LQSVENCPEALLQLELPLDLAVLQDIEQELCNEEKSIISEYEEDLEFDESCLRRMLA-- 128

  Fly    96 NEWYALGEKNLETLYAEPDEQQKEVLCPVCQIKNLRHHKGAFICECGIRFE-HSANM--EQLQIL 157
             ||.|                 ..::||||...|||.......|.||:... ||.::  ::|:..
Mouse   129 -EWEA-----------------NSLICPVCIKYNLRIMNSVVTCPCGLHIPVHSTDLTEQKLRAC 175

  Fly   158 LQQQIASHELQCTQALRFFIEPASGQ---LYDMCGSCDYFSSV 197
            |::.:..|.:.|.....|.:...:.:   |...|.:||.::.:
Mouse   176 LEENVNEHSVHCPHTPVFSVTGGTEEKPSLLMNCLTCDTWAVI 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ripalpha	NP_609351.1	RPA_interact_C	121..196	CDD:464305	21/80 (26%)
Rpain	NP_081462.1	RPA_interact_N	8..47	CDD:464304	10/39 (26%)
		RPA_interact_M	59..127	CDD:434193	14/69 (20%)
		RPA_interact_C	136..217	CDD:464305	21/80 (26%)
		Mediates nuclear export. /evidence=ECO:0000250	164..180		3/15 (20%)