Protein Alignment Sur and BPT1

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_013086.1
• Gene: BPT1 / 850645
• SGDID: S000003938
• Length: 1559
• Species: Saccharomyces cerevisiae
• Alignment Length: 2248
• Identity: 503/2248 - (22%)
• Similarity: 806/2248 - (35%)
• Gaps: 830/2248 - (36%)

  Fly    92 PHQNVRNLNRLFQS--SPRDLNYLVVIGSGELW-------------------------------N 123
            |......||..|.|  |.....:.::|||.:||                               |
Yeast    18 PDSGTNALNPCFISVISAWQAVFFLLIGSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTN 82

  Fly   124 ALF-STLLTLMLMLYHRMVER------KKATVFLYAS-------------TAVEALTFALLSNEL 168
            ..| |||:...|.|..:..:|      |||   ||.:             .|....||: :.|:|
Yeast    83 VCFQSTLIICELALVSQSSDRVYPFILKKA---LYLNLLFNLGISLPTQYLAYFKSTFS-MGNQL 143

  Fly   169 FEL---VRYEDFLELQ-----------TCLVAMSAMCMVSLAMLDGLT--VYKECYHD--DYLDD 215
            |..   :..:.||.||           |.:...:||.:..|.:.:.:.  :|..|..:  :.|.:
Yeast   144 FYYMFQILLQLFLILQRYYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSE 208

  Fly   216 YGKIGYKHSMATFYSKSCFWWLTPLLWLGYKE---------PLELEDLGQMKLEDSARSHYDHFL 271
            |.|....:......|...|.|:..|:...|:.         ||...||....:....:::::
Yeast   209 YYKKNGWYPPVHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWE--- 270

  Fly   272 YIYTEKKKKSNSSPSLWYCYIKNSWQMFALGGILKLAGDLFALIGPLAIQKIVEYIEQLYAQASE 336
               .||....|   |||....|:..:..::..:.:...||.:::.|   |.:..:|:.|..:.|.
Yeast   271 ---LEKWLNRN---SLWRAIWKSFGRTISVAMLYETTSDLLSVVQP---QFLRIFIDGLNPETSS 326

  Fly   337 --PPAKSPGNEVANVLLSTSRILGTEFDEVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAAIT 399
              ||..  |..:|..|...|.:      .||.||...:.|:.:
Yeast   327 KYPPLN--GVFIALTLFVISVV------SVFLTNQFYIGIFEA---------------------- 361

  Fly   400 QGALSQASTHILNMTGIRIKTSLQGLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDS 464
                           |:.|:.||..|:|:|||.|                 |.:..:||
Yeast   362 ---------------GLGIRGSLASLVYQKSLRL-----------------TLAERNEK------ 388

  Fly   465 MATPEHVDNPSEPNISHDIGSITNHMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGISA 529
                             ..|.|.|.|:.|...|..||.........|.:|.||:..||..|| .|
Yeast   389 -----------------STGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLG-KA 435

  Fly   530 VIGSIACIVIMTPLQFFIGNAMSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQE 594
            |||.:..:.||.|:..|:...:.|.::....|.|.|:|.|.:.|..||.|||.||:|..:.::..
Yeast   436 VIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNH 500

  Fly   595 ARR-KELKYLNKDATFWTLMAVLTHIATVLITFVTLGVYVWLHRDQEFDLNASRLFSSLALFQQL 658
            .|. .|||...|......|:....:...:::|..|.|::. |..|.  .|:.:.:|.||:||..|
Yeast   501 VRNDMELKNFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFS-LFSDS--PLSPAIVFPSLSLFNIL 562

  Fly   659 TVPLLIFPITVPIIIAARVSTRRLERFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNM 723
            ...:...|..:..||...||..||:.||.|.||...|         :.:.|.|.|
Yeast   563 NSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSF---------IERIDPSAD---------- 608

  Fly   724 TMRTAQAENRLNEKRLAQKSQTPELATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLR 788
                        |:.|      |.:..|:...|..::|..      |..:.|.|....:
Yeast   609 ------------ERAL------PAIEMNNITFLWKSKEVL------TSSQSGDNLRTDE------ 643

  Fly   789 NTPYVAIRPPKMRGSVMERPVEFSVIRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMP 853
                             |..:..|.|..:|.|.:.
Yeast   644 -----------------ESIIGSSQIALKNIDHFE------------------------------ 661

  Fly   854 VVQLHVPGIIVPKGKLTIVVGKNGSGKTSLLSALLMEMPLLAGN------MFWHKTCTISYVSQQ 912
                      ..:|.|..|||:.|:||::.|.|:|.::|.::|:      ....::.:::|.||:
Yeast   662 ----------AKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQE 716

  Fly   913 PWLLNDTIRENILFGESFRPKRYDFVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIA 977
            .|::|.::|||||||..|....||..::||.|.||::::|.||.:::||:||::||||:.|:::|
Yeast   717 SWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLA 781

  Fly   978 RAIYSSANVVIMDDPLASLDNEVGEHIFQHCI--REMLQKSNRTFILVTQQLHRIKEAEYLIAIK 1040
            ||:||.|::.::||.|:::|.||.::|.::.:  :..|.| |:|.||.|..:..:|.::.:.|::
Yeast   782 RAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLK-NKTIILTTNTVSILKHSQMIYALE 845

  Fly  1041 DGRVEACGSYADIELMQPRITAEWNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRS 1105
            :|.:...|:|.|:                 ...||                    |.|||
Yeast   846 NGEIVEQGNYEDV-----------------MNRKN--------------------NTSKL----- 868

  Fly  1106 ISVTMDANVACHADAIDGSGCISVANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSR 1170
                                        ..::||.|.
Yeast   869 ----------------------------KKLLEEFDS---------------------------- 877

  Fly  1171 HLMYDVPLPIDECQGDDVIMRPRRRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRS 1235
                    |||.....||                  .:.||
Yeast   878 --------PIDNGNESDV------------------QTEHR------------------------ 892

  Fly  1236 VLATSCSSYAESSVDGGDLATAAPEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEE 1300
                     :||.||                         :||               .:|.:|.
Yeast   893 ---------SESEVD-------------------------EPL---------------QLKVTES 908

  Fly  1301 ARRSNTSSESPLDDHVRGSFQQFLRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASI 1365
            .......:||.|:          |.:.:.||::
Yeast   909 ETEDEVVTESELE----------LIKANSRRAS-------------------------------- 931

  Fly  1366 LATDGNKNETQSEEKPKKCVNIDSKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAE 1430
            |||        ...:|.....:||.:.|
Yeast   932 LAT--------LRPRPFVGAQLDSVKKT------------------------------------- 951

  Fly  1431 VAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAAGLPIITIFFITALIWQCLRVYTDIWLQ 1495
                        |:.|..||  .|::...|||.||:|.|:..:.:||:..::.:...:..:.||:
Yeast   952 ------------AQKAEKTE--VGRVKTKIYLAYIKACGVLGVVLFFLFMILTRVFDLAENFWLK 1002

  Fly  1496 QWSNVHGRVASKGHVVLHPSEQDHEVTYYFRMY-------AAISCVCIIMALVSTPAGQYAGCNA 1553
            .||..:.:..|           :..|..:..:|       ||.:.:..||.|:      |.....
Yeast  1003 YWSESNEKNGS-----------NERVWMFVGVYSLIGVASAAFNNLRSIMMLL------YCSIRG 1050

  Fly  1554 RRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAVIDKKIAATGQRLLQFTLLCLSAILINV 1618
            .:.||:.:.::::...:.||:.||:|||:||||:||..:|..:    |.:..|....:...|:.|
Yeast  1051 SKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNL----QYIFSFFFKSILTYLVTV 1111

  Fly  1619 TIT----PWILVLTLPICGAYYLIQKFYRCSARELQRIENATNSPVISHLSETIQGVTTIRAFNQ 1679
            .:.    ||.||..:.:...|...|.||...:|||:|:.:.:.||::|.:||::.|.:.|.|::.
Yeast  1112 ILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDH 1176

  Fly  1680 QTRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTS 1744
            ..||..:.:::::.|........:::|||.|.|..:|..||....:.||  |:::.:|..
Yeast  1177 FERFIYLNYEKIQYNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILAL--ATMNTKRQL----- 1234

  Fly  1745 PSASASPSPFETYAVTKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAH 1809
                                    |..:|||.::|:|.|...|.|:|:....:|....|||||..
Yeast  1235 ------------------------SSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVE 1275

  Fly  1810 YAQGQDADADADADADADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGD 1874
            |.
Yeast  1276 YC--------------------------------------------------------------- 1277

  Fly  1875 QQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSV 1939
                                                                             
Yeast  1278 ----------------------------------------------------------------- 1277

  Fly  1940 IKDKQLPP--QQDDKDKKVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNL 2002
                :|||  |..:.:|:   |:|             :||.:|.|.|.|.|.:|......|::|:
Yeast  1278 ----ELPPEAQSINPEKR---PDE-------------NWPSKGGIEFKNYSTKYRENLDPVLNNI 1322

  Fly  2003 TLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVH 2067
            .:||...:::||.||||:|||:|.|:||.:|:.|.|.|.||.:||..|...:||:.|:|||||..
Yeast  1323 NVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQ 1387

  Fly  2068 LFNATIRENLDPHGYFQDLQLWNCLELAQLKEFVNGHL---PLG-------------LDTVICDG 2116
            .|..|::.||||...:.:.:|...:|.|.||..:...|   |.|             ||..|.:.
Yeast  1388 AFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINEN 1452

  Fly  2117 GLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLAFRGRTIITIAHRLTTI 2181
            |.|||.|.|||||||||:|..|..|||||||:.:|..|:..:.......|:.|||:|||||:.|:
Yeast  1453 GSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTV 1517

  Fly  2182 LDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKG 2219
            ||.|::||||||.:.|..:|.:|...:.|:|..|.|||
Yeast  1518 LDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLCEKG 1555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
BPT1	NP_013086.1	MRP_assoc_pro	222..1556	CDD:188098	460/2040 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24223
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100