Protein Alignment Sur and ABCC8

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_001326629.1
• Gene: ABCC8 / 821679
• AraportID: AT3G21250
• Length: 1470
• Species: Arabidopsis thaliana
• Alignment Length: 2259
• Identity: 471/2259 - (20%)
• Similarity: 775/2259 - (34%)
• Gaps: 918/2259 - (40%)

  Fly    43 IFLLLFGLMFVCSRYKKCHKTLLTFH---NGR------AAISLLLLALNSFDLARIFLPHQNVRN 98
            :||.:|.|..:.|    |..|    |   .||      .|:: :..|:.||    |||.    ..
plant    39 LFLCIFYLFLIAS----CVST----HFIVRGRKKGWIFVAVA-ICCAITSF----IFLG----VG 86

  Fly    99 LNRLFQ--SSPRDLNYLVVIGSGELWNALFSTLLTLMLMLYHRMVERKKATVFLYASTAVEALTF 161
            ||.|..  :...:::::.....|.:|.:|..:||.             ..:.::....:|..::|
plant    87 LNSLIHGGNDVTEISWVACFVEGIIWVSLAVSLLV-------------NGSKWVNILVSVWWVSF 138

  Fly   162 ALL-----SNELFE--LVRYEDFLELQTCLVAMSAMCM----VSLAMLD----GLTVYKECYHDD 211
            |||     |..|.:  .:|..|.|.|...|:.:....|    .|.|..|    ||:       |.
plant   139 ALLDLVAKSGILLQGNGIRILDILTLPMSLLLLLCSWMNLRSSSAAAQDCSVTGLS-------DP 196

  Fly   212 YL-DDYGKIGYKHSMATFYSKSCFWWLTPLLWLGYKEPLELEDLGQMKLEDSARSHYDHFLYIY- 274
            .| .:..|...:.:.|.|:|...|.|:.|||.||:|:||..||:..:..||.|:..|..|...:
plant   197 LLTKNPRKESARLATAGFFSILSFSWMNPLLSLGFKKPLSPEDIPSVVPEDEAQLAYKKFSQAWD 261

  Fly   275 ------TEKKKKSNSSPSLWYCYIKNSWQMFALGGILKLAGDLFALIG-PLAIQKIVEYIEQLYA 332
                  :..|:::....::...|.|.: ...|:...|:    .||::. ||.:...|:|
plant   262 TLLGDESSTKERNLVFRAVVKVYFKEN-IFIAVFAFLR----TFAVVSLPLMLYVFVDY------ 315

  Fly   333 QASEPPAKSPGNEVANVLLSTSRILGTEFDEVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAA 397
                  |.|...::.|...:.:                                 |:..:.|:.:
plant   316 ------ANSDHRDLRNGFFNLA---------------------------------CLVMLKLVES 341

  Fly   398 ITQGALSQASTHILNMTGIRIKTSLQGLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKND 462
            :|......||    ..:|:||:::|....|:|.|.|::.|                     :|.
plant   342 LTMRHWYFAS----RRSGMRIRSALMVAAYKKQLKLSSLG---------------------RKR- 380

  Fly   463 DSMATPEHVDNPSEPNISHDIGSITNHMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGI 527
                              |..|.|.|::..|...:.||....|..|::..::.:...:|:..:|.
plant   381 ------------------HSSGEIVNYIAVDAYRMGEFLWWFHSGWSLSLQLLLSTAVLFGVVGA 427

  Fly   528 SAVIGSI---ACIVIMTPLQFFIGNAMSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFL 589
            .|..|.|   .|.::..|....:.|..::  .:||  .|:||:...:.|..:|||||.:|::.|.
plant   428 GAFPGLILLLLCGLLNLPFAKMLQNCQTQ--FMIA--QDKRLRSTSEILNSMKVIKLQSWEDEFK 488

  Fly   590 KKIQEARRKELKYLNK--------DATFWTLMAVLTHIATVLITFVTLGVYVWLHRDQEFDLNAS 646
            |||:..|..|..:|.|        ...:|.       ..|::.:.|.||..:.    :...||||
plant   489 KKIESCRDDEFTWLAKAQLTKAFGSFLYWM-------SPTIVSSVVFLGCALL----KSAPLNAS 542

  Fly   647 RLFSSLALFQQLTVPLLIFPITVPIIIAARVSTRRLERFLKSSEIQKQFEGIRNMARILSKSDAS 711
            .:|:.||..:.::.|:.|.|..:..||...||.:||..||...|::
plant   543 TIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFLLDDELK------------------- 588

  Fly   712 LDMYETQEKSNMTMRTAQAENRLNEKRLAQKSQTPELATNSTPLLQNAEESAEDISPSTVQELGH 776
                                                        :...|.|..|.|.:
plant   589 --------------------------------------------MDEIERSGLDASGT------- 602

  Fly   777 NKLVQQRRELLRNTPYVAIRPPKMRGSVMERPVEFSVIRARNTDSWRRDSLLLKMPDDIAVSIND 841
                                                                       ||.|..
plant   603 -----------------------------------------------------------AVDIQV 608

  Fly   842 GLFTWQPQSQMPVVQ-LHVPGIIVPKGKLTIVVGKNGSGKTSLLSALLMEMPLLAGNMFWHKTC- 904
            |.|.|:|::::|.:: :|:.   :..|:...|.|..|:||:|||.|:|.|:|.::|.:   |..
plant   609 GNFGWEPETKIPTLRNIHLE---IKHGQKVAVCGPVGAGKSSLLHAVLGEIPKVSGTV---KVFG 667

  Fly   905 TISYVSQQPWLLNDTIRENILFGESFRPKRYDFVLEACALKPDIELMPRGDLSIIGERGINISGG 969
            :|:||||..|:.:.|||:|||:|:....:||:..::||||..|:.....|||:.||:||||:|||
plant   668 SIAYVSQTSWIQSGTIRDNILYGKPMESRRYNAAIKACALDKDMNGFGHGDLTEIGQRGINLSGG 732

  Fly   970 QRQRIAIARAIYSSANVVIMDDPLASLDNEVGEHIFQHCIREMLQKSNRTFILVTQQLHRIKEAE 1034
            |:|||.:|||:|:.|:|.::|||.:::|......:|..|:.:.|::  :|.||||.|:..:.|.:
plant   733 QKQRIQLARAVYADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKE--KTVILVTHQVEFLSEVD 795

  Fly  1035 YLIAIKDGRVEACGSYADIELMQPRITAEWNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSK 1099
            .::.:::|.:...|.|.::.:|                               |..::.|.|
plant   796 QILVMEEGTITQSGKYEELLMM-------------------------------GTAFQQLVN--- 826

  Fly  1100 LGLQRSISVTMDANVACHADAIDGSGCISVANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRS 1164
                            .|.||                      |:|
plant   827 ----------------AHNDA----------------------VTV------------------- 834

  Fly  1165 SIYGSRHLMYDVPLPIDECQGDDVIMRPRRRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISG 1229
                       :||..:|..||
plant   835 -----------LPLASNESLGD------------------------------------------- 845

  Fly  1230 DVLSRSVLATSCSSYAESSVDGGDLATAAPEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPD 1294
                                                                             
plant   846 ----------------------------------------------------------------- 845

  Fly  1295 VKKSEEARRSNTSSESPLDDHVRGSFQQFLRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVV 1359
                                              :|:..|
plant   846 ----------------------------------LRKEGK------------------------- 851

  Fly  1360 HFPASILATDGNKNETQSEEKPKKCVNIDSKETTINCDDNCYSASDKELRANVTSSPADQEQHNE 1424
                                                         |:|:| |:|
plant   852 ---------------------------------------------DREIR-NMT----------- 859

  Fly  1425 RHVLAEVAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAA-GLPIITIFFITALIWQCLRV 1488
              |:.::..|..:..:|..:|..:.|::.|.:....:|.||..: |
plant   860 --VVEKIEEEIEKTDIPGVQLTQEEEKESGYVGMKPFLDYIGVSRG------------------- 903

  Fly  1489 YTDIWLQQWSNVHGRVASKGHVVLHPSEQDHEVTYYFRMYAAISCVCIIM-----ALVST-PAG- 1546
                |...||:|.|:|   |.||...:.     ||:......|..:...|     :::|| .||
plant   904 ----WCLLWSSVLGQV---GFVVFQAAS-----TYWLAFAIGIPKITNTMLIGVYSIISTLSAGF 956

  Fly  1547 --------QYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAVIDKKIAATGQRL 1603
                    .:.|..|.:.........:....:.||..||:|||:.|.|:|:.|:|..:.
plant   957 VYARAITTAHLGLKASKAFFSGFTNAVFKAPMLFFDSTPVGRILTRASSDLNVLDYDVP------ 1015

  Fly  1604 LQFTLLC-----LSAILINVTITPW-ILVLTLPICGAYYLIQKFYRCSARELQRIENATNSPVIS 1662
            ..|..:.     |:|.|:.:|...| ::::.|....|..::|.:|..|||||.||...|.:||::
plant  1016 FAFIFVVAPAVELTAALLIMTYVTWQVIIIALLALAATKVVQDYYLASARELIRINGTTKAPVMN 1080

  Fly  1663 HLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTA 1727
            :.:||..||.|||||....||.:.....::|:.:.:.|.|.:..|:.:.::.|....:|...:..
plant  1081 YAAETSLGVVTIRAFGTAERFFKNYLNLVDADAVLFFLSNAAMEWVILRIETLQNVTLFTCALLL 1145

  Fly  1728 LTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRP----SPSLVGLAINYTLLV---PI 1785
            :                                     |.|    :|.||||:::|.|.:   .:
plant  1146 I-------------------------------------LIPKGYIAPGLVGLSLSYALTLTQTQV 1173

  Fly  1786 YL-NWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSSNEDVSAEVDRS 1849
            :| .|...|...:.    |||||..|.
plant  1174 FLTRWYCTLSNSII----SVERIKQYM-------------------------------------- 1196

  Fly  1850 SQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVTGDG 1914
                              ::.|:
plant  1197 ------------------NIPEE------------------------------------------ 1201

  Fly  1915 NHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLERYQSVPISWPQR 1979
                   |||              :|.||: ||.                          |||..
plant  1202 -------PPA--------------IIDDKR-PPS--------------------------SWPSN 1218

  Fly  1980 GDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHIYIDD 2044
            |.||...:.:||......|:..::.....|.|:|:.||||||||:|..:||.:::...|.|.||.
plant  1219 GTIHLQELKIRYRPNAPLVLKGISCTFREGTRVGVVGRTGSGKSTLISALFRLVEPASGCILIDG 1283

  Fly  2045 VDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQDLQLWNCLELAQLKEFVNGHLPLGL 2109
            :||.:|...:||.:||||||:..||...||.||||.|.:.|.::|..||..|||..:: :||..|
plant  1284 IDISKIGLKDLRMKLSIIPQEPTLFRGCIRTNLDPLGVYSDDEIWKALEKCQLKTTIS-NLPNKL 1347

  Fly  2110 DTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLAFRGRTIITI 2174
            |:.:.|.|.|.|.|.|||.||.|.:|:.:..|||||||:.:||:|::.:.:.....|...|:||:
plant  1348 DSSVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASIDSATDAIIQRIIREEFADCTVITV 1412

  Fly  2175 AHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKGASKW 2223
            |||:.|::|.|.::||..|.:||...|.:|.:.: |.|..|:   |..|
plant  1413 AHRVPTVIDSDMVMVLSFGDLVEYNEPSKLMETD-SYFSKLV---AEYW 1457

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010