Protein Alignment Sur and ABCC7

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_187917.3
• Gene: ABCC7 / 820498
• AraportID: AT3G13100
• Length: 1493
• Species: Arabidopsis thaliana
• Alignment Length: 2277
• Identity: 466/2277 - (20%)
• Similarity: 771/2277 - (33%)
• Gaps: 921/2277 - (40%)

  Fly    38 FTFFSIF--LLLFGLMFVCSRYKK----------------------------CHKTLLTFHNGRA 72
            |..||||  |||..:||....|||                            |.:||       :
plant    21 FPMFSIFFNLLLLLVMFGSCVYKKRLGWENSDAFTNERFKDMSLTYNKLVVICCETL-------S 78

  Fly    73 AISLLLLALNSFDLARIFLPHQNVRNLNRLFQSSPRDLNYLVVIGSGELWNAL------------ 125
            |::.:||.|:.|:|      |:|..:.:.|       :..|.::.:...|.|:
plant    79 ALNSVLLLLSCFNL------HKNGWDRSEL-------MILLDLLFTALSWGAISFYIRSQFTYSH 130

  Fly   126 ---FSTLLTLMLMLY-----HRMVERKKATVFLYASTAVEALTFALLSNELFELVRYEDFLELQT 182
               |..||.:..:||     :|::    ..:.||...  |.::..||.:::. .|....|| ..:
plant   131 DQKFPILLRVWWVLYFMFSCYRLL----VDIALYKKQ--ELVSVHLLLSDVL-AVSVGLFL-CYS 187

  Fly   183 CLVAMSAMCMVSLAMLDGL----------TVYKECYHDDYLDDYGKIGYKHSMATFYSKSCFWWL 237
            ||........::|.:.:.|          :|..:...||      ::....|.|.|.|...|.|:
plant   188 CLQKQGQGERINLLLEEPLLNGAESSAATSVQLDKAEDD------EVVTPFSNAGFLSHVSFSWM 246

  Fly   238 TPLLWLGYKEPLELEDLGQMKLEDSARSHYDHFLYIYTEKKKKSNSSPSL-WYCYIK----NSWQ 297
            :||:.||.::.::.||:.|:...|.|    :...:|:..|.:..:....: .|..||    :.|:
plant   247 SPLIVLGNEKIIDSEDVPQVDNSDRA----EKLFWIFRSKLEWDDGERRITTYKLIKALFFSVWR 307

  Fly   298 MFALGGILKLAGDLFALIGPLAIQKIVEYIEQLYAQASEPPAKSPGNEVANVLLSTSRILGTEFD 362
            ...|..:......:...:.|..:...|:|
plant   308 DILLSTLFAFVYTVSCYVAPYLMDTFVQY------------------------------------ 336

  Fly   363 EVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAAITQGALSQASTHILNMTGIRIKTSLQGLIY 427
                  ::..|.||:       .|..:.....:|.:.:....:.....|...||.:::.|..:||
plant   337 ------LNGQRQYSN-------QGVVLVTTFFVAKLVECQARRNWYFRLQKAGIGMRSVLVSMIY 388

  Fly   428 RKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDSMATPEHVDNPSEPNISHDIGSITNHMTE 492
            .|.|.|                                        |......|..|.|.|.||.
plant   389 EKGLTL----------------------------------------PCYSKQGHTSGEIINLMTV 413

  Fly   493 DTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGISAVIGSIACIVIM---TPL----QFFIGNA 550
            |...|..|...:|..|.:..:|::.:.:||.:||:.::....|..::|   .||    :.|.||.
plant   414 DAERISAFSWYMHDPWILVLQISLALLILYRSLGLGSIAAFAATFLVMLGNIPLAKLEEKFQGNL 478

  Fly   551 MSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQEARRKELKYLNKDATFWTLMAV 615
            |...        |.|:|:..:.|:.::::||..|:..||.||.:.|..|..:|.|   |....|.
plant   479 MESK--------DNRMKKTSEALLNMRILKLQGWEMKFLHKILDLRGIEAGWLKK---FVYNSAA 532

  Fly   616 LTHIATVLITFVT---LGVYVWLHRDQEFDLNASRLFSSLALFQQLTVPLLIFPITVPIIIAARV 677
            ::.:.....:||:   .|..:.|    :..|.:.::.::||.|:.|..|:...|.|:.:|:..:|
plant   533 ISSVLWAAPSFVSATAFGACMLL----KIPLESGKIIAALATFRILQTPIYKLPDTISMIVQTKV 593

  Fly   678 STRRLERFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNMTMRTAQAENRLNEKRLAQK 742
            |..|:..||...::|:  :|:..:....||.|
plant   594 SLDRIATFLCLDDLQQ--DGMERLPSGSSKMD--------------------------------- 623

  Fly   743 SQTPELATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLRNTPYVAIRPPKMRGSVMER 807
                                                                             
plant   624 ----------------------------------------------------------------- 623

  Fly   808 PVEFSVIRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMPVVQLHVPGIIVPKGKLTIV 872
                                         |.:::|.|:|...|  |:..|......:|.|....:
plant   624 -----------------------------VEVSNGAFSWDDSS--PIPTLKDIRFKIPHGMNIAI 657

  Fly   873 VGKNGSGKTSLLSALLMEMPLLAGNMFWHKTC-TISYVSQQPWLLNDTIRENILFGESFRPKRYD 936
            .|..||||:||||::|.|:|.::||:   |.| ..:|::|.||:.:..:.||||||:..:.:.|.
plant   658 CGTVGSGKSSLLSSILGEVPKISGNL---KVCGRKAYIAQSPWIQSGKVEENILFGKPMQREWYQ 719

  Fly   937 FVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDNEVG 1001
            .|||||:|..|:|:.|..|.::|||||||:||||:|||.||||:|..|::.:.|||.:::|...|
plant   720 RVLEACSLNKDLEVFPFRDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDAHTG 784

  Fly  1002 EHIFQHCIREMLQKSNRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAEWNA 1066
            .|:|:..:..:|:  |:|.|.||.||..:.||:.::.:||||:...|.|.:|
plant   785 SHLFKEVLLGLLR--NKTVIYVTHQLEFLPEADLILVMKDGRITQAGKYNEI------------- 834

  Fly  1067 IIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGCISVAN 1131
                                      |......:.|           |..|.||:....
plant   835 --------------------------LESGTDFMEL-----------VGAHTDALAAVD------ 856

  Fly  1132 MQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRPRRRH 1196
                          ||..|:||.
plant   857 --------------SYEKGSASA------------------------------------------ 865

  Fly  1197 TLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATAAPEP 1261
                                                                             
plant   866 ----------------------------------------------------------------- 865

  Fly  1262 RVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQFLRR 1326
                                                     :|.||.||.:
plant   866 -----------------------------------------QSTTSKESKV-------------- 875

  Fly  1327 MSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNIDSKE 1391
                                                       .|..|.|.|:.|.
plant   876 -------------------------------------------SNDEEKQEEDLPS--------- 888

  Fly  1392 TTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGKI 1456
                                                             |..:|..:.||:.||:
plant   889 -------------------------------------------------PKGQLVQEEEREKGKV 904

  Fly  1457 SDDIYLMYIRAA-GLPIITIFFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVLHPSEQDHE 1520
            ...:|..|::.| |..::.|..:..:::|.|.:.::.|: .|              :.|..:|.:
plant   905 GFTVYQKYMKLAYGGALVPIILVVQILFQVLNIGSNYWM-AW--------------VTPVSKDVK 954

  Fly  1521 ---------VTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVT 1576
                     :.|.|...|:..|: ::.|::|...|..........:|.:    |...::.||..|
plant   955 PLVSGSTLILVYVFLATASSFCI-LVRAMLSAMTGFKIATELFNQMHFR----IFRASMSFFDAT 1014

  Fly  1577 PLGRIVNRFSNDMAVIDKKIAATGQRLLQFTLLCLSAILINVTI-----TPW-ILVLTLPICGAY 1635
            |:|||:||.|.|.:.:|.::.:      ||:.|.::|:.|...|     ..| :|::.:|:..|.
plant  1015 PIGRILNRASTDQSAVDLRLPS------QFSNLAIAAVNILGIIGVMGQVAWQVLIVFIPVIAAC 1073

  Fly  1636 YLIQKFYRCSARELQRIENATNSPVISHLSETIQGVTTIRAFNQQTRF-TEIL-----FKRLEAN 1694
            ...:::|..:||||.|:...:.||::.|.|||:.|:||||:|:|:.|| |:|:     :.||..:
plant  1074 TWYRQYYISAARELARLSGISRSPLVQHFSETLSGITTIRSFDQEPRFRTDIMRLNDCYSRLRFH 1138

  Fly  1695 TIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAV 1759
            .|      ::..||...||.| ..:.|..::..|.
plant  1139 AI------SAMEWLCFRLDLL-STVAFALSLVILV------------------------------ 1166

  Fly  1760 TKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADA 1824
              |..|...:||..|||:.|.|.:......::..|.|:|....||||:..|
plant  1167 --SVPEGVINPSFAGLAVTYALNLNSLQATLIWTLCDLENKMISVERMLQY-------------- 1215

  Fly  1825 DADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCG 1889
                 .|:..|||
plant  1216 -----IDIPSEPS---------------------------------------------------- 1223

  Fly  1890 YRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDK 1954
                                                                             
plant  1224 ----------------------------------------------------------------- 1223

  Fly  1955 KVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTG 2019
            .|:....|.:          |||.||:|...|:.:||......|:..||.....|.:.||.||||
plant  1224 LVIESTRPEK----------SWPCRGEITICNLQVRYGPHLPMVLRGLTCTFRGGLKTGIVGRTG 1278

  Fly  2020 SGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQ 2084
            .|||:|..:||.:::...|.|.||.::|..|...:||:|||||||:..:|..|:|.||||...:.
plant  1279 CGKSTLIQTLFRIVEPAAGEIRIDGINILTIGLHDLRSRLSIIPQEPTMFEGTVRSNLDPLEEYA 1343

  Fly  2085 DLQLWNCLELAQLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSV 2149
            |.|:|..|:..||.:.:. ...|.||:.:.:.|.|.|.|.|||:||.|.:|:.|..|:|||||:.
plant  1344 DDQIWEALDKCQLGDEIR-KKELKLDSPVSENGQNWSVGQRQLVCLGRVLLKRSKVLILDEATAS 1407

  Fly  2150 LDSSTESALLKAADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRG 2214
            :|::|::.:.:.....|.|.|:||||||:::::|.|.:::||||.|.|..:|..|.:.:.|.|..
plant  1408 VDTATDTLIQETLRQHFSGCTVITIAHRISSVIDSDMVLLLDQGLIEEHDSPARLLEDKSSSFSK 1472

  Fly  2215 LL 2216
            |:
plant  1473 LV 1474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
ABCC7	NP_187917.3	PLN03232	34..1474	CDD:215640	457/2262 (20%)
		ABC_membrane	309..578	CDD:294371	69/372 (19%)
		ABCC_MRP_domain1	624..824	CDD:213217	85/206 (41%)
		ABC_membrane	925..1199	CDD:294371	79/338 (23%)
		ABCC_MRP_domain2	1239..1459	CDD:213211	89/220 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010