Protein Alignment Sur and ABCC2

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_001189675.1
• Gene: ABCC2 / 818031
• AraportID: AT2G34660
• Length: 1623
• Species: Arabidopsis thaliana
• Alignment Length: 2139
• Identity: 480/2139 - (22%)
• Similarity: 779/2139 - (36%)
• Gaps: 837/2139 - (39%)

  Fly   122 WNALFSTLLTLM--LMLYHRMVERKK----ATVFLYAS-TAVEALTFALLSNELFELVRYEDFLE 179
            |...|:.:..|:  ::|.:.::..|:    ..::||.| ...:.|...||...|..|..|..::.
plant   141 WYVRFAVIYALVGDMVLLNLVLSVKEYYSSYVLYLYTSEVGAQVLFGILLFMHLPNLDTYPGYMP 205

  Fly   180 LQTCLVAMSAMCMVSLAMLDGLTVYKECYHDDYLDDYGKIG-------YKHSMATFYSKSCFWWL 237
            :::..|                        |||  :|.:|.       .||  |..:.|..|.|:
plant   206 VRSETV------------------------DDY--EYEEISDGQQICPEKH--ANIFDKIFFSWM 242

  Fly   238 TPLLWLGYKEPLELEDLGQMKLEDSARSHYDHFLYIYTEKKKKSNSSPSLWYCYIKNS------- 295
            .||:.||.|.||..:|:..:...|...:.:..|.:.:.::.:|    |..|.....|:
plant   243 NPLMTLGSKRPLTEKDVWYLDTWDQTETLFTSFQHSWDKELQK----PQPWLLRALNNSLGGRFW 303

  Fly   296 WQMFALGGILKLAGDLFALIGPLAIQKIVEYIEQLYAQASEPPAKSPGNEVANVLLSTSRILGTE 360
            |     ||..|:..|....:|||.:.::::.:::      :.||
plant   304 W-----GGFWKIGNDCSQFVGPLLLNQLLKSMQE------DAPA--------------------- 336

  Fly   361 FDEVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAAITQGALSQASTHILNM--TGIRIKTSLQ 423
                              |.     |:..|:.:.:..:. |.|.:|. :..|:  .|.|::::|.
plant   337 ------------------WM-----GYIYAFSIFVGVVF-GVLCEAQ-YFQNVMRVGYRLRSALI 376

  Fly   424 GLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDSMATPEHVDNPSEPNISHDIGSITN 488
            ..::||||.|                    |::.::|                    ...|.|||
plant   377 AAVFRKSLRL--------------------TNEGRRK--------------------FQTGKITN 401

  Fly   489 HMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGISAVIGSIACIVIMTPLQFFIGNAMSK 553
            .||.|..::.:....:|..|:.||:|.:.:.|||..||::::||:: .:|:|.|||..|.:.|.|
plant   402 LMTTDAESLQQICQSLHTMWSAPFRIIIALILLYQQLGVASLIGAL-LLVLMFPLQTVIISKMQK 465

  Fly   554 NAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQEARRKELKYLNKDATFWTLMAVLTH 618
            ..:.....||:|:..:::.|..:..:|..||:..|..|:|..|..||.:..|......|...:.:
plant   466 LTKEGLQRTDKRIGLMNEVLAAMDTVKCYAWENSFQSKVQTVRDDELSWFRKSQLLGALNMFILN 530

  Fly   619 IATVLITFVTLGVYVWLHRDQEFDLNASRLFSSLALFQQLTVPLLIFPITVPIIIAARVSTRRLE 683
            ...||:|.|:.||:..|..    ||..:|.|:||:||..|..||.:.|..:..::.|.||.:|||
plant   531 SIPVLVTIVSFGVFTLLGG----DLTPARAFTSLSLFAVLRFPLFMLPNIITQVVNANVSLKRLE 591

  Fly   684 RFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNMTMRTAQAENRLNEKRLAQKSQTPEL 748
            ..|.:.|
plant   592 EVLATEE---------------------------------------------------------- 598

  Fly   749 ATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLRNTPYVAIRPPKMRGSVMERPVEFSV 813
                                               |.||.|.                 |:|
plant   599 -----------------------------------RILLPNP-----------------PIE--- 608

  Fly   814 IRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMPVVQLHVPGIIVPKGKLTIVVGKNGS 878
                              |.:.|:||.:|.|:|..:...|.  |....:.||.|.|..|||..|.
plant   609 ------------------PGEPAISIRNGYFSWDSKGDRPT--LSNINLDVPLGSLVAVVGSTGE 653

  Fly   879 GKTSLLSALLMEMP-------LLAGNMFWHKTCTISYVSQQPWLLNDTIRENILFGESFRPKRYD 936
            |||||:||:|.|:|       .|.|        :::||.|..|:.|.|:|:|||||..|..::|:
plant   654 GKTSLISAILGELPATSDAIVTLRG--------SVAYVPQVSWIFNATVRDNILFGSPFDREKYE 710

  Fly   937 FVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDNEVG 1001
            ..::..:||.|:||:|.|||:.|||||:||||||:||:::|||:||:::|.|.||||::||..||
plant   711 RAIDVTSLKHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVG 775

  Fly  1002 EHIFQHCI-REMLQKSNRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAEWN 1065
            :.:|:.|| ||:.||   |.:|||.|||.:.:.:.::.:.:|.|:..|:|.::....|...
plant   776 QQVFEKCIKRELGQK---TRVLVTNQLHFLSQVDRIVLVHEGTVKEEGTYEELSSNGPLFQ---- 833

  Fly  1066 AIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGCISVA 1130
                                      :|::|..|:                            ..
plant   834 --------------------------RLMENAGKV----------------------------EE 844

  Fly  1131 NMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRPRRR 1195
            ..:.|...|.|| :...|:.|.
plant   845 YSEENGEAEADQ-TAEQPVANG------------------------------------------- 865

  Fly  1196 HTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATAAPE 1260
                     |||      ||                                .:||.
plant   866 ---------NTN------GL--------------------------------QMDGS-------- 875

  Fly  1261 PRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQFLR 1325
                                             |.|||:|
plant   876 ---------------------------------DDKKSKE------------------------- 882

  Fly  1326 RMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNIDSK 1390
                                                        |||       |..|.|.|..:
plant   883 --------------------------------------------GNK-------KGGKSVLIKQE 896

  Fly  1391 ETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGK 1455
                                                                       ||:.|.
plant   897 -----------------------------------------------------------ERETGV 902

  Fly  1456 ISDDIYLMYIRA-AGLPIITIFFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVLHPSEQDH 1519
            :|..:...|..| .|..::.:..:..::.:..||.:..||.:|::.             .:.:.|
plant   903 VSWRVLKRYQDALGGAWVVMMLLLCYVLTEVFRVTSSTWLSEWTDA-------------GTPKSH 954

  Fly  1520 EVTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNR 1584
            ...:|..:||.:|...:::.|.::.....:...|.:.|||.:|.:||...:.||...|||||:||
plant   955 GPLFYNLIYALLSFGQVLVTLTNSYWLIMSSLYAAKKLHDNMLHSILRAPMSFFHTNPLGRIINR 1019

  Fly  1585 FSNDMAVIDKKIAATGQRLL-QFTLLCLSAILINV--TITPWILVLTLPICGAYYLIQKFYRCSA 1646
            |:.|:..||:.:|......: |.:.|..:.:||.:  |::.|.:   :|:...:|....:|:.:|
plant  1020 FAKDLGDIDRTVAVFVNMFMGQVSQLLSTVVLIGIVSTLSLWAI---MPLLVLFYGAYLYYQNTA 1081

  Fly  1647 RELQRIENATNSPVISHLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNT-SHRWLGV 1710
            ||::|:::.:.|||.:...|.:.|::||||:....|..:|..:.:: |.|.:.|:|. ::||||:
plant  1082 REVKRMDSISRSPVYAQFGEALNGLSTIRAYKAYDRMADINGRSMD-NNIRFTLVNMGANRWLGI 1145

  Fly  1711 SLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKS--PSELRPSPSLV 1773
            .|:.|||.:::      |||                         ::||.::  ....:...|.:
plant  1146 RLETLGGLMIW------LTA-------------------------SFAVMQNGRAENQQAFASTM 1179

  Fly  1774 GLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSS 1838
            ||.::|.|.:...|..|::|.:..|....:|||:
plant  1180 GLLLSYALNITSLLTGVLRLASLAENSLNAVERV------------------------------- 1213

  Fly  1839 NEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANAD 1903
                                                                             
plant  1214 ----------------------------------------------------------------- 1213

  Fly  1904 KLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLER 1968
                      ||::..  ||                    :.||        |:..|.|
plant  1214 ----------GNYIEI--PP--------------------EAPP--------VIENNRP------ 1232

  Fly  1969 YQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVL 2033
                |..||..|.|.|::|.|||..|...|:..::..|....::||.||||:|||||..:||.::
plant  1233 ----PPGWPSSGSIKFEDVVLRYRPQLPPVLHGVSFFIHPTDKVGIVGRTGAGKSSLLNALFRIV 1293

  Fly  2034 QTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQDLQLWNCLELAQLK 2098
            :..:|.|.|||.|:.:....:||..|.||||...||:.|:|.||||.|...|..||..||.|.||
plant  1294 EVEKGRILIDDCDVGKFGLMDLRKVLGIIPQSPVLFSGTVRFNLDPFGEHNDADLWESLERAHLK 1358

  Fly  2099 EFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAAD 2163
            :.:..: |||||..:.:.|.|.|.|.||||.|:||:||.|..|||||||:.:|..|::.:.|...
plant  1359 DTIRRN-PLGLDAEVSEAGENFSVGQRQLLSLSRALLRRSKILVLDEATAAVDVRTDALIQKTIR 1422

  Fly  2164 LAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEK-GAS 2221
            ..|:..|::.|||||.||:|.|:::|||.||:.|..:|..|...|||.|..:::. ||:
plant  1423 EEFKSCTMLIIAHRLNTIIDCDKILVLDSGRVQEFSSPENLLSNEGSSFSKMVQSTGAA 1481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
ABCC2	NP_001189675.1	PLN03130	1..1623	CDD:215595	480/2139 (22%)
		ABC_membrane	309..570	CDD:279056	82/357 (23%)
		ABCC_MRP_domain1	614..815	CDD:213217	92/213 (43%)
		ABC_membrane	925..1179	CDD:294371	74/301 (25%)
		ABCC_MRP_domain2	1240..1460	CDD:213211	99/220 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3850
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24223
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110