Protein Alignment Sur and abcb11a

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: XP_009303249.2
• Gene: abcb11a / 797269
• ZFINID: ZDB-GENE-050517-13
• Length: 1320
• Species: Danio rerio
• Alignment Length: 1440
• Identity: 257/1440 - (17%)
• Similarity: 448/1440 - (31%)
• Gaps: 579/1440 - (40%)

  Fly   830 KMPDDIAV-SINDGLFTWQPQSQMPVVQLHVPGIIVPKGKLTIVVGKNGSGKTSLLSALLM---- 889
            |:..||.. |:|   |.:..:.::.:  |....|:|..|:.|..||.:|||||:.:..:..
Zfish   408 KVKGDIEFHSVN---FNYPSRPEVKI--LDDLNIVVKAGETTAFVGPSGSGKTTTIQLIQRFYDP 467

  Fly   890 --EMPLLAG------NMFWHKTCTISYVSQQPWLLNDTIRENILFGE-----------SFRPKRY 935
              .|..|.|      |:.|.:: .|..|.|:|.|...||.|||.:|.           :.:...|
Zfish   468 SEGMVSLDGHDIRSLNIQWLRS-LIGVVEQEPVLFATTIAENIRYGRAGVTMQEIIEAAKQANAY 531

  Fly   936 DFVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDNEV 1000
            :|::.          :|:...:::||.|..:||||:||||||||:..:..::::|...::||||
Zfish   532 NFIMS----------LPQTFDTLVGEGGGQMSGGQKQRIAIARALVRNPRILLLDMATSALDNE- 585

  Fly  1001 GEHIFQHCIREMLQKS--NRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAE 1063
                .:..::|.|.|:  .||.|.:..:|..|:.|:.::..:.||....|:
Zfish   586 ----SEAVVQEALDKARQGRTTISIAHRLSTIRNADVIVGFEHGRAVERGT-------------- 632

  Fly  1064 WNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGC-I 1127
                                                                 |:..:|..|. .
Zfish   633 -----------------------------------------------------HSQLLDKKGVYF 644

  Fly  1128 SVANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRP 1192
            ::..:|:
Zfish   645 TLVTLQN---------------------------------------------------------- 651

  Fly  1193 RRRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATA 1257
                                                                     .|.|..|.
Zfish   652 ---------------------------------------------------------QGKDTDTD 659

  Fly  1258 APEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQ 1322
            .||...:|     .||....|                    ||.||.::           ||::.
Zfish   660 KPENTAES-----RVTEEAEL--------------------EELRRFSS-----------GSYES 688

  Fly  1323 FLRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNI 1387
            .|||.|:.:            .:||:..||.:    ..|.:.:...:.:.|..:|:.|.|:.:
Zfish   689 VLRRRSLSQ------------LSNSLSVISGK----FDFNSDLFEMEESDNNKKSKGKAKEDI-- 735

  Fly  1388 DSKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERK 1452
                                       .||                       |:||:.     |
Zfish   736 ---------------------------KPA-----------------------PVARIL-----K 745

  Fly  1453 YGKISDDIYLMYIRAAGL-----PIITIFFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVL 1512
            |.:......|:....|.:     |:..:.|                    |.:.|..:     :.
Zfish   746 YNRPEWPYMLLGSIGAAINGSLNPMYALLF--------------------SQILGTFS-----IP 785

  Fly  1513 HPSEQDHEVTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVTP 1577
            .|.:|..::.....::..|..|......:...:...:|....|.|.....|.:|.:.:.:|. .|
Zfish   786 DPDDQRRQINGICILFVVIGVVSFFSQFLQGYSFAKSGELLTRRLRKFGFQAMLKQEIGWFD-DP 849

  Fly  1578 L---GRIVNRFSNDMAVIDKKIAATGQR--LLQFTLLCLSAILINVTITPWILVLT----LPICG 1633
            :   |.:..|.:.:.:::.   .|||.:  ::..:|..:.|..|......|.|.|.    ||:.|
Zfish   850 MNSPGALTTRLATNASMVQ---GATGSQIGMIVNSLTNIGASFIIAYYFSWKLSLVVTCFLPLIG 911

  Fly  1634 AYYLIQKFYRCSARELQRIENATNSPV-----ISHLSETIQGVTTIRAFNQQTRFTEILFKRLEA 1693
            ...:.|      ::.|..:.|...:.:     :|  ||.:..:.||....::..|.....|:|:|
Zfish   912 LSGVFQ------SKMLTGLANEDKTALEAAGQVS--SEAMSNIRTIAGLAKEKHFVAQFEKQLQA 968

  Fly  1694 NTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYA 1758
               .|..........|:...: ..|::|:|     .|||.....:.         .|....:...
Zfish   969 ---PYKAAKKKAYVYGICFAF-ARCVIFMA-----YAASFRYGGYL---------VSHEGLQYMM 1015

  Fly  1759 VTKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADAD 1823
            |.:..|.|..|.:.:|.|.::|   |.|        |..::.|..:.::
Zfish  1016 VFRVISALVTSATALGRASSFT---PDY--------AKAKISAAQLFQL---------------- 1053

  Fly  1824 ADADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDC 1888
                    ||..|..|   .::.:..|.:|...||
Zfish  1054 --------LDRVPKIN---VSKTEGQSWNDFKGKV------------------------------ 1077

  Fly  1889 GYRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKD 1953
                                                                             
Zfish  1078 ----------------------------------------------------------------- 1077

  Fly  1954 KKVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRT 2018
                          .::....::|.|.|:              .|:..|.:.:..||.:...|.:
Zfish  1078 --------------EFKGCRFTYPSRPDV--------------QVLRGLVVSVHPGQTLAFVGSS 1114

  Fly  2019 GSGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYF 2083
            |.|||:....|........|.:.||......|....||:::.|:.|:..||:.:|.||:......
Zfish  1115 GCGKSTSVQLLERFYDPDEGQVLIDGRPSDSISVPFLRSQIGIVSQEPVLFDCSIAENIQYGDNS 1179

  Fly  2084 QDLQLWNCLELAQ---LKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDE 2145
            :.:.:...::.|:   |.:||. .||...:|.:...|..||.|.:|.:.:||||:|....|:|||
Zfish  1180 RTVSMEEIIDAAKKAYLHDFVM-TLPDKYETQVGAQGSQLSRGQKQRIAIARAIVRNPKILLLDE 1243

  Fly  2146 ATSVLDSSTESALLKAADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGS 2210
            |||.||:.:|..:..|.|.|.:|||.|.|||||:||...|.:.|:.||.::|.|...||...:.:
Zfish  1244 ATSALDTESEKTVQAALDEARQGRTCIVIAHRLSTIQSADIIAVMSQGEVIEKGTHDELMAKKAA 1308

  Fly  2211 VFRGLLEKGA 2220
            .:: |:..||
Zfish  1309 YYK-LVTTGA 1317

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000