Protein Alignment Sur and Abcb10

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_062425.1
• Gene: Abcb10 / 56199
• MGIID: 1860508
• Length: 715
• Species: Mus musculus
• Alignment Length: 922
• Identity: 189/922 - (20%)
• Similarity: 329/922 - (35%)
• Gaps: 296/922 - (32%)

  Fly  1344 ATNSILSISEESPPVV--------------HFPASILATDGNKNETQSEEKPKKCVNIDSKETTI 1394
            |.:|.:.::.|..|:|              .|||.:....|...:..:....::|..:.......
Mouse    25 AVSSRIWLASEWTPLVRAWTSLIHKPGSGLRFPAPLSGLPGGVGQWATSSGARRCWVLAGPRAAH 89

  Fly  1395 NCDDNCYSASD---KELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGKI 1456
            ........|:.   ::|..:....||...:.....:|..|..|.||.|..:..||:.:
Mouse    90 PLFARLQGAAATGVRDLGNDSQRRPAATGRSEVWKLLGLVRPERGRLSAAVGFLAVSS------- 147

  Fly  1457 SDDIYLMYIRAAGLPIITI---FFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVLHPSE-Q 1517
                           :||:   ||:..:|        |:                 :..:||| .
Mouse   148 ---------------VITMSAPFFLGRII--------DV-----------------IYTNPSEGY 172

  Fly  1518 DHEVTYYFRMYAAISCVCIIMAL---VSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVTPLG 1579
            ...:|   |:.|.::||.:..|.   :.....|.:|.:....|...|..:||.:.:.||..|..|
Mouse   173 GDSLT---RLCAVLTCVFLCGAAANGIRVYLMQSSGQSIVNRLRTSLFSSILRQEVAFFDKTRTG 234

  Fly  1580 RIVNRFSNDMAVIDKKI-------------AATGQRLLQFTLLCLSAILINVTITPWILVLTLPI 1631
            .::||.|:|.|::.:.:             |:.|..::.|....|:..:::|  .|.|.||.: |
Mouse   235 ELINRLSSDTALLGRSVTENLSDGLRAGAQASVGVGMMFFVSPSLATFVLSV--VPPISVLAV-I 296

  Fly  1632 CGAYYLIQKFYRCSARELQRIENATNSPVISH---LSETIQGVTTIRAFNQQTRFTEILFKRLEA 1693
            .|.|             |:::..||...:...   ..|.|..:.|||||.::  .||:
Mouse   297 YGRY-------------LRKLSKATQDSLAEATQLAEERIGNIRTIRAFGKE--MTEV------- 339

  Fly  1694 NTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYA 1758
                       .::.| .:|.|    :.:|...||..|...
Mouse   340 -----------EKYTG-RVDQL----LQLAQKEALARAGFF------------------------ 364

  Fly  1759 VTKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADAD 1823
                        ...||:.|..:|..:|...:  |:....|..|.:.....||
Mouse   365 ------------GAAGLSGNLIVLSVLYKGGL--LMGSAHMTVGELSSFLMYA------------ 403

  Fly  1824 ADADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDC 1888
                                              .:.|.:              ||
Mouse   404 ----------------------------------FWVGLS--------------IG--------- 411

  Fly  1889 GYRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKD 1953
                    |..:...:|..|  .|.|..|         .:.:|         :..:||     .:
Mouse   412 --------GLSSFYSELMKG--LGAGGRL---------WELLE---------RQPRLP-----FN 443

  Fly  1954 KKVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRT 2018
            :.:||..:..:....:::|..::|.|.::              :|..:.:|.||:|....:.|.:
Mouse   444 EGMVLDEKTFQGALEFRNVHFTYPARPEV--------------SVFQDFSLSIPSGSVTALVGPS 494

  Fly  2019 GSGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYF 2083
            |||||::...|..:.....|.:.:|..||:::.|..||:::..:.|:..||:.::.||:   .|.
Mouse   495 GSGKSTVVSLLLRLYDPNSGTVSLDGHDIRQLNPVWLRSKIGTVSQEPVLFSCSVAENI---AYG 556

  Fly  2084 QD-------LQLWNCLELAQLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCL 2141
            .|       .|:....|:|...||:.. .|.|.|||:.:.|:.||.|.:|.:.:|||:|:....|
Mouse   557 ADNLSSVTAQQVERAAEVANAAEFIRS-FPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKIL 620

  Fly  2142 VLDEATSVLDSSTESALLKAADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQ 2206
            :||||||.||:..|..:.:|.|....|||::.|||||:||.:.:.:.|||.|:|.|.|...||..
Mouse   621 LLDEATSALDAENEHLVQEALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLL 685

  Fly  2207 LEGSVFRGLLEK 2218
            ....::|.|:.|
Mouse   686 KPNGLYRKLMNK 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
Abcb10	NP_062425.1	3a01208	8..694	CDD:273363	187/917 (20%)
		ABC_membrane	142..403	CDD:279056	71/389 (18%)
		ABC_MTABC3_MDL1_MDL2	458..698	CDD:213216	82/258 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000