Protein Alignment Sur and haf-7

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_506645.1
• Gene: haf-7 / 190115
• WormBaseID: WBGene00001817
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 892
• Identity: 183/892 - (20%)
• Similarity: 318/892 - (35%)
• Gaps: 292/892 - (32%)

  Fly  1370 GNKNE----TQSEEKPKKCVNIDSKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAE 1430
            |.|.|    .:..|..:...|.:.:..|.:.:....:|:.....::.:.|.:..|:.|:
 Worm   144 GKKKEGAEYERLTENTETAANTNVENGTASTNGTASTATPTAATSSTSRSSSTDEEDND------ 202

  Fly  1431 VAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAAGLPIITIFFITALIWQCLRVYTDIWLQ 1495
                           |:..|.|..:              ||::|      .:||.:::.:..|
 Worm   203 ---------------AVSKEEKEKR--------------LPLLT------HLWQIVKLCSVQW-- 230

  Fly  1496 QWSNVHGRVASKGHVVL---------HPSEQDHEVTYYFRM--YAAISCVCIIMALVS-TPAG-- 1546
            :|       .|..:|:|         .|:.....::...||  :..:...||::|.|. |.|.
 Worm   231 KW-------FSAAYVLLFVDCILNLIEPALYSQMMSTAIRMKSFDVLKRACIVLAAVQFTEATVN 288

  Fly  1547 -------QYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAVIDKKIAATGQRLL 1604
                   |||.....||:...|.:.|||:.:.||.....|::::|.:.|...|...:....:..:
 Worm   289 TVRYICMQYAERLTARNIRVSLFRAILHQDISFFDDNKTGQLMSRITKDSESISNSLPVYIETTV 353

  Fly  1605 --QFTLLCLSAILINVTITPWILVL----TLPICGAYYLIQKFYRCSARELQRIENATNSPVISH 1663
              .|.|...:.|:...:   |.|.:    |.||   ..|..|||.....:|...||...:.....
 Worm   354 NNSFMLFGSAPIMFYYS---WQLAISTFVTFPI---ILLTTKFYGLIVEKLSEKENDATAVSNET 412

  Fly  1664 LSETIQGVTTIRAFNQQ-------TRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLGGCIVF 1721
            :.|.:..:.|:|:|..:       ||.|:..|| :...|:.:          |...:|      |
 Worm   413 VEEVLSAIRTVRSFAAEKIENMRYTRDTDAWFK-ISTKTVVF----------GTFFNY------F 460

  Fly  1722 VATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRPSPSLVGLAINYTLLVPIY 1786
            .||:..:....:..   |....:.:....|....||                   |.|...:...
 Worm   461 WATMWNIEDVIIYL---YGGYLTLNGRMEPDALLTY-------------------IFYHWRLHSA 503

  Fly  1787 LNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSSNEDVSAEVDRSSQ 1851
            ||....|.:|:....||..::.|.                     ::.:|        |:|
 Worm   504 LNAFSSLFSDVMKTIGSSRKVIHI---------------------MNRQP--------ELD---- 535

  Fly  1852 SDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVTGDGNH 1916
                                                      :|.|.|.
 Worm   536 ------------------------------------------YEFGTET---------------- 542

  Fly  1917 LNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLERYQSVPISWPQRGD 1981
                                                 .::|                      |:
 Worm   543 -------------------------------------PEIV----------------------GN 548

  Fly  1982 IHFDNVSLRYEGQKQ-NVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTR-GHIYIDD 2044
            |.|::|...|..:|. ||::.:.|.|..|:.|.:.|.:|:|||:| :||.....|.: |.|.||.
 Worm   549 IIFEDVEFAYPTRKNANVLNKINLSIDPGKTIALVGPSGNGKSTL-VSLIQQFYTPQSGRILIDG 612

  Fly  2045 VDIQRIRPDELRTRLSIIPQDVHLFNATIRENL---DPHGYFQDLQLWNCLELAQLKEFVNGHLP 2106
            ..||.|......|.::::.|:..||:.|:|||:   ..:|..:|:.  ...|:|.:.|||: .:.
 Worm   613 TPIQNIDHLHYHTNIALVAQEPTLFSGTVRENILYGLENGTDEDMM--RVAEMANVHEFVS-KME 674

  Fly  2107 LGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLAFRGRTI 2171
            .|.||...:.|:.:|.|.:|.:.:|||::|....|:||||||.|||.:|:.:.:|.:...|.||:
 Worm   675 KGYDTKCGEKGVQMSGGQKQRIAIARALIRDPRVLILDEATSALDSESEAMVQEALNRCARERTV 739

  Fly  2172 ITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEK 2218
            :.|||||:|:...||:.|:::|.:.|.||..||.:....::..|:.|
 Worm   740 LVIAHRLSTVRSADRIAVIEKGNVTEMGNHEELMKNTEGLYYKLVSK 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
haf-7	NP_506645.1	3a01208	17..784	CDD:273363	181/888 (20%)
		ABC_membrane	238..494	CDD:279056	60/300 (20%)
		ABC_MTABC3_MDL1_MDL2	549..787	CDD:213216	85/242 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910