DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sur and haf-1

DIOPT Version :9

Sequence 1:	NP_001334732.1	Gene:	Sur / 34350	FlyBaseID:	FBgn0028675	Length:	2223	Species:	Drosophila melanogaster
Sequence 2:	NP_503098.2	Gene:	haf-1 / 178522	WormBaseID:	WBGene00001811	Length:	677	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	78/264 - (29%)
Similarity:	136/264 - (51%)	Gaps:	18/264 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1963 ARKLERYQSVPISWPQRG--------DIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTG 2019
            :|.||...:.||.....|        .|.|:|||..|.|:|: .:.|::..||.|:...:.|.:|
Worm   386 SRLLELKNAQPIMNLNSGIKKTDITTSIQFENVSFAYAGRKK-TLENISFDIPRGKITAVIGPSG 449

  Fly  2020 SGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENL-----DP 2079
            |||||:...:..:.....|.:.:|.||::.:.....|..:..:.|:..||..:||||:     .|
Worm   450 SGKSSIANLMLRLYDPADGRVTVDGVDLRDLNATTWRHAIGTVGQEPVLFTCSIRENILMGTEHP 514

  Fly  2080 HGYFQDLQLWNCLELAQLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLD 2144
            ....| .:|....:||...:|:.| ...|.:|::.:.|..||.|.:|.:.:|||::.....::||
Worm   515 EKVSQ-YELEEAAQLANALDFIQG-FENGFETMVGEHGCKLSGGQKQRIAIARALISKPKIMILD 577

  Fly  2145 EATSVLDSSTESALLKAAD--LAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQL 2207
            ||||.||::::..:....|  |.....|::.|||||.|:...|:::.:::|||...|...|:.::
Worm   578 EATSALDATSDYLIRMTLDNLLKNHNLTVLVIAHRLATMQQADQVVYVNRGRIEGQGTFDEMMKI 642

  Fly  2208 EGSV 2211
            :.|:
Worm   643 QNSI 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
haf-1	NP_503098.2	MdlB	82..641	CDD:224055	77/257 (30%)
		ABC_membrane	93..363	CDD:294371
		P-loop_NTPase	413..641	CDD:304359	71/230 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910