Protein Alignment Sur and Abcc5

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: NP_446376.1
• Gene: Abcc5 / 116721
• RGDID: 70913
• Length: 1436
• Species: Rattus norvegicus
• Alignment Length: 2077
• Identity: 467/2077 - (22%)
• Similarity: 774/2077 - (37%)
• Gaps: 728/2077 - (35%)

  Fly   183 CLVAMSAMCMVSLAMLDGLTVYKECYHDDYLD-DYGKIGYKHSM------------------ATF 228
            |..|:.....|....|| ::|:.   |...|| ::.|..|.|.:                  |..
  Rat    46 CQDALETAARVEGLSLD-ISVHS---HLQILDEEHTKGKYHHGLSALKPFRTTTKHQHPVDNAGL 106

  Fly   229 YSKSCFWWLTPLLWLGYKE-PLELEDLGQMKLEDSARSHYDHFLYIYTEKKKKSNSSPS-----L 287
            :|...|.||:||..:.:|: .|.:||:..:...:|:..:......::.|:..:.....:     :
  Rat   107 FSYMTFSWLSPLAQVVHKKGELLMEDVWPLSKYESSDVNCRRLERLWQEELNEVGPDAASLRRVV 171

  Fly   288 W-YCYIKNSWQMFALGGILKLAGDLFALIGP-LAIQKIVEYIEQLYAQASEPPAKSPGNEVANVL 350
            | :|..:....:..| .|.:|||    ..|| ..::.::|     |.||:|          :|:.
  Rat   172 WIFCRTRLILSIVCL-MITQLAG----FSGPAFVVKHLLE-----YTQATE----------SNLQ 216

  Fly   351 LSTSRILGTEFDEVFGTNIDKVRIYSSTWSDLLANGWCIAWIVLLAAITQGALSQASTHILNMTG 415
            .|...:||....||       ||    :||  ||..|.:.:                     .||
  Rat   217 YSLLLVLGLLLTEV-------VR----SWS--LALTWALNY---------------------RTG 247

  Fly   416 IRIKTSLQGLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDSMATPEHVDNPSEPNIS 480
            :|::.::..:.::|.|.|                     .:.|:|:
  Rat   248 VRLRGAVLTMAFKKILKL---------------------KNIKEKS------------------- 272

  Fly   481 HDIGSITNHMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLY--MNLGISAVIGSIACIVIMTPL 543
              :|.:.|..:.|.:.:.|...:.......|  :..::.::|  :.||.:..:|| |..::..|.
  Rat   273 --LGELINICSNDGQRMFEAAAVGSLLAGGP--VVAILGMIYNVIILGPTGFLGS-AVFILFYPA 332

  Fly   544 QFFIGNAMSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQEARRKELKYLNKDAT 608
            ..|:....:.........||:|::::::.|..||.||:.||.:.|.:.:|:.|.:|.:.|.|...
  Rat   333 MMFVSRLTAYFRRKCVAATDDRVQKMNEVLTYIKFIKMYAWVKAFSQCVQKIREEERRILEKAGY 397

  Fly   609 FWTLMAVLTHIATVLITFVTLGVYVWLHRDQEFDLNASRLFSSLALFQQLTVPLLIFPITVPIII 673
            |.::...:..|..|:.:.||..|::.|    .|||.|::.|:.:.:|..:|..|.:.|.:|..:.
  Rat   398 FQSITVGVAPIVVVIASVVTFSVHMTL----GFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLS 458

  Fly   674 AARVSTRRLERFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNMTMRTAQAENRLNEKR 738
            .|.|:   ::|| ||..:.::...|:|..   :.....::|.......:.:..:.|:..:|..|
  Rat   459 EASVA---VDRF-KSLFLMEEVHMIKNKP---ASPHIKIEMKNATLAWDSSHSSTQSSPKLTPK- 515

  Fly   739 LAQKSQTPELATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLRNTPYVAIRPPKMRGS 803
            :.:..:.|:.....:..||:.|..|              .|.:|:..||.::.
  Rat   516 VKKDKRAPKGKKEKSRQLQHTEHQA--------------VLAEQKGHLLLDSD------------ 554

  Fly   804 VMERPVEFSVIRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMPVVQLHVPGIIVPKGK 868
              |||                     ...::....|:.|....|.       .|:...:.:.:||
  Rat   555 --ERP---------------------SPEEEEGKQIHAGSMRLQR-------TLYNIDLEIEEGK 589

  Fly   869 LTIVVGKNGSGKTSLLSALLMEMPLLAGNMFWHKTCTISYVSQQPWLLNDTIRENILFGESFRPK 933
            |..:.|..|||||||:||:|.:|.||.|::  ..:.|.:||:||.|:||.|:|:|||||:.|..:
  Rat   590 LVGICGSVGSGKTSLISAILGQMTLLEGSI--AVSGTFAYVAQQAWILNATLRDNILFGKEFDEE 652

  Fly   934 RYDFVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDN 998
            ||:.||.:|.|:||:.::|..||:.|||||.|:||||||||::|||:||..::.|:||||::||.
  Rat   653 RYNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDA 717

  Fly   999 EVGEHIFQHCIREMLQKSNRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAE 1063
            .||.|||...||:.|:  ::|.:.||.||..:.:.:.:|.:|:|.:...|::.  |||
  Rat   718 HVGNHIFNSAIRKRLK--SKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHE--ELM------- 771

  Fly  1064 WNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGCIS 1128
                                                                             
  Rat   772 ----------------------------------------------------------------- 771

  Fly  1129 VANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRPR 1193
                                         ||....::|:.:. |:.:.| |::
  Rat   772 -----------------------------NLNGDYATIFNNL-LLGETP-PVE------------ 793

  Fly  1194 RRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATAA 1258
                        .||....||                              ::.|.|.|
  Rat   794 ------------INSKKEASG------------------------------SQKSQDKG------ 810

  Fly  1259 PEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQF 1323
            |:|                               ..|||.:..:
  Rat   811 PKP-------------------------------GSVKKEKAVK--------------------- 823

  Fly  1324 LRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNID 1388
                                        |||...|                 |.|||
  Rat   824 ----------------------------SEEGQLV-----------------QVEEK-------- 835

  Fly  1389 SKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKY 1453
                                                           |:.|:|.:
  Rat   836 -----------------------------------------------GQGSVPWS---------- 843

  Fly  1454 GKISDDIYLMYIRAAGLPIITIFFITALIWQCLRV----YTDIWLQQW---SNVHGRVASKGHVV 1511
                  :|.:||:|||.|:.   |:..::...|.|    ::..||..|   .:.:..|.......
  Rat   844 ------VYWVYIQAAGGPLA---FLVIMVLFMLNVGSTAFSTWWLSYWIKQGSGNSTVFEGNRSS 899

  Fly  1512 LHPSEQDHE-VTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQV 1575
            :..|.:|:. :.||..:||....|.:|:..:...........|...|||:|.:.||...:.||..
  Rat   900 VSDSMRDNPFLQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDT 964

  Fly  1576 TPLGRIVNRFSNDMAVIDKKIAATGQRLLQFTLLCLSAILINVTITPWILVLTLPICGAYYLIQK 1640
            ||.|||:||||.||..:|.::....:..:|..:|....:.:...:.||.||...|:...:.::..
  Rat   965 TPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLLILFSVLHI 1029

  Fly  1641 FYRCSARELQRIENATNSPVISHLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNTSH 1705
            ..|...|||:|::|.|.||.:||::.:|||:.||.|:|::..|.....:.|:.|...:.|...:.
  Rat  1030 VSRVLIRELKRLDNITQSPFLSHITSSIQGLATIHAYNKRQEFLHRYQELLDDNQAPFFLFTCAM 1094

  Fly  1706 RWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRPSP 1770
            |||.|.||     ::.:|.:|  |...:....|.:.   |||.|
  Rat  1095 RWLAVRLD-----LISIALIT--TTGLMIVLMHGQI---PSAYA--------------------- 1128

  Fly  1771 SLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHE 1835
               ||||:|.:.:.....:.|:|.::.|....|||||.||.:....:|.|.
  Rat  1129 ---GLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPAR-------------- 1176

  Fly  1836 PSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEA 1900
                                                                             
  Rat  1177 ----------------------------------------------------------------- 1176

  Fly  1901 NADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARK 1965
                                                   ||:| .||.
  Rat  1177 ---------------------------------------IKNK-APPH----------------- 1184

  Fly  1966 LERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLF 2030
                     .|||.|:|.|:|..:||......|:..::..|...::|||.|||||||||||::||
  Rat  1185 ---------DWPQEGEITFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALF 1240

  Fly  2031 GVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQDLQLWNCLELA 2095
            .:::.:.|.|.||.|.|..|...:||::|:||||:..||:.|:|.||||...:.:.|:|:.||..
  Rat  1241 RLVELSGGCIKIDGVRISDIGLADLRSKLTIIPQEPVLFSGTVRSNLDPFNQYTEEQIWDALERT 1305

  Fly  2096 QLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLK 2160
            .:||.: ..|||.|::.:.:.|.|.|.|.|||||:|||:||....|:|||||:.:|:.|:..:.:
  Rat  1306 HMKECI-AQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQE 1369

  Fly  2161 AADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKGASK 2222
            ....||...|::||||||.|:|..||::||.||::||...|..|...:.|.|..:.....:|
  Rat  1370 TIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRFYAMCAAAENK 1431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
Abcc5	NP_446376.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	12..38
		PLN03130	100..1424	CDD:215595	454/2010 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	499..569		16/119 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	795..822		12/93 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010