Protein Alignment Sur and abcb10

DIOPT Version :9

• Sequence 1: NP_001334732.1
• Gene: Sur / 34350
• FlyBaseID: FBgn0028675
• Length: 2223
• Species: Drosophila melanogaster
• Sequence 2: XP_001343218.3
• Gene: abcb10 / 100003744
• ZFINID: ZDB-GENE-040525-2
• Length: 710
• Species: Danio rerio
• Alignment Length: 835
• Identity: 180/835 - (21%)
• Similarity: 313/835 - (37%)
• Gaps: 252/835 - (30%)

  Fly  1414 SSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAAGLPIITI--- 1475
            |:..|..|.::..|..|.:.::..:|:|:..   :..:|..:::.........|.|..:|:.
Zfish    88 STSTDSNQTSKSVVNQESSAKTTADSLPVPS---EDVKKLLQLAHPQRWRLTAAVGFLVISSTVT 149

  Fly  1476 ----FFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVLHPSEQDHEVTYYFRMYAAISCVCI 1536
                ||:..:|   ..:||.                      |:|.         ..::::.:|:
Zfish   150 MSAPFFLGKVI---DTIYTS----------------------PTED---------FSSSLTSLCL 180

  Fly  1537 IMALVSTPAG----------QYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAV 1591
            ::..|....|          |.:|....|.|.:.|..:||.:.|.||..|..|.::||.|.|.|:
Zfish   181 MLTGVFLCGGAANAARVYLMQISGQQIVRKLRESLFSSILKQELGFFDKTRTGELINRLSADTAI 245

  Fly  1592 IDKKIA---ATGQRLLQFTLLCLSAIL-INVTITPWILVLTLPICGAYYLIQKFYRCSARELQ-R 1651
            :.:.:.   :.|.|.|......:..:| ::.::..::|::..||.....:..:|.|..:|..| .
Zfish   246 VGRCLTDNLSDGLRSLAQAGAGVGMMLYVSPSLAAFVLMVVPPIACLAVIFGRFLRSISRRTQDA 310

  Fly  1652 IENATNSPVISHLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLG 1716
            :..||..     ..|.|..:.|:|||.::  .||:                   :.....:|:
Zfish   311 LAEATQL-----AEERISNLRTVRAFGKE--LTEV-------------------QKYSQKVDH-- 347

  Fly  1717 GCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRPSPSLVGLAINYTL 1781
              |..:|...|:.:|..                       |.||             ||:.|..:
Zfish   348 --IFELAKKEAVVSAGF-----------------------YGVT-------------GLSGNVII 374

  Fly  1782 LVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSSNEDVSAEV 1846
            |..:|...:  |:|...|..|.:.....||
Zfish   375 LSVLYKGGL--LMASEAMTVGQLSSFLMYA----------------------------------- 402

  Fly  1847 DRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVT 1911
                       .:.|.:.|                               |..:...:|..|  .
Zfish   403 -----------FWVGISIA-------------------------------GFSSFYSELMKG--L 423

  Fly  1912 GDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLERYQSVPISW 1976
            |.|..|                   ..:|..|...|..:.    :||.:|..
Zfish   424 GAGTRL-------------------WELIDRKPEFPLNEG----LVLTSELL------------- 452

  Fly  1977 PQRGDIHFDNVSLRYEGQKQN-VISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHI 2040
              :|::.|.|||..|..:|.: :..:|:|.:|||..:.:.|.:|||||||...|..:.....|.:
Zfish   453 --KGELEFRNVSFAYPTRKDSPIFQDLSLHVPAGSVLAVVGSSGSGKSSLVSLLLRLYDPDSGIV 515

  Fly  2041 YIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENL-----DPHGYFQDLQLWNCLELAQLKEF 2100
            .:|..||:.:.|..||:.:..:.|:..||:.:|.||:     ||.....: .::...::|...:|
Zfish   516 SVDGHDIRDLNPYWLRSHIGTVSQEPVLFSCSIAENIAYGAPDPSQVTVE-DIYRAAQIANAHDF 579

  Fly  2101 VNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLA 2165
            :. ..|.|.|||:.:.|:.||.|.:|.:.:|||:|:....|:||||||.||:..|..:.:|.:..
Zfish   580 IQ-EFPKGYDTVVGEKGVLLSGGQKQRVAIARALLKNPKILLLDEATSALDAENEFLVQEALERL 643

  Fly  2166 FRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKGA 2220
            ..|||::.|||||:||...|.:.||||.|::|.|:..:|...:..:||.|:||.|
Zfish   644 MDGRTVLIIAHRLSTIQSADSVAVLDQHRVMEIGSHSQLLANDQGLFRKLMEKQA 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur	NP_001334732.1	None
abcb10	XP_001343218.3	MsbA_rel	123..697	CDD:131259	171/794 (22%)
		ABC_membrane	141..402	CDD:279056	66/362 (18%)
		P-loop_NTPase	457..697	CDD:304359	85/241 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000