DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13137 and aaas

DIOPT Version :9

Sequence 1:	NP_609350.2	Gene:	CG13137 / 34349	FlyBaseID:	FBgn0032188	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_998390.1	Gene:	aaas / 378454	ZFINID:	ZDB-GENE-030912-4	Length:	499	Species:	Danio rerio

Alignment Length:	388	Identity:	88/388 - (22%)
Similarity:	151/388 - (38%)	Gaps:	77/388 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 EILERISQTRGWKTSVIRFIECHPSSSLMAF-LTNDDVVLICDKNYDCPTKIQSVRQKDTTCVAF 139
            |::...||...|..|.:|....||.:...|. |.:|.:.:....:...||    ::.:....|..
Zfish   128 EMVAEFSQMLDWSDSAVRSFSWHPHTDKFAVALLDDSIKIYKPHSSTAPT----LKHRCQRSVCA 188

  Fly   140 RPWSQTC--EFAVGCAAGICLWSDSRRLNANRNIRRMMGTHHLQVLQDKGHNYVTSMQWNEDGTI 202
            ..|...|  ..||.|.:.:.:|...   .|:.:.|...|.  .|||...||:.:||:.|:..|::
Zfish   189 LQWKPLCGSALAVACQSCLLIWHVD---PASLSTRPSSGC--AQVLSHPGHSPITSIAWSPTGSL 248

  Fly   203 LVTAAFGSSHIMLWEPDCQQKIRLIPNPKSLGSFSLLRFSPDFHVLFCASCDAGASLCQLNRSK- 266
            ||:|:...:.:|:|:...:..:.|  .....|..:.|.:|||...|..|:..|   |.::..::
Zfish   249 LVSASPVDTAMMVWDVAAESCVPL--RRVGGGGVTFLSWSPDGSRLLAATPSA---LFRVWETRM 308

  Fly   267 WKLKQ---ILGQQRIQSAVWTTCGSTLLYACYGSTRVYSCT--------------SDGEDSVFLR 314
            |..::   :.|.  .|||.|:..|:.||.:..|...:|:.:              :|..::.|..
Zfish   309 WTCERWPCLKGS--CQSACWSPDGACLLLSIQGERLIYALSFSDLTGGPKAATVVADLSETSFPG 371

  Fly   315 PQSIWRVQLIMDLQLVTTCAGQRLCCGEPQCLAMDPLGIYMASIFK--EQSF---VLLCILHTSR 374
            |:                  |.....||...|:.||.|..:|.:.|  .||.   .::.:..|..
Zfish   372 PE------------------GDLTVGGEVCSLSWDPRGERLAVLLKGDAQSTDHPSVIAVFKTRC 418

  Fly   375 WGNVKLLPVEFIYCDMDGDQYPAYISFGVLKAEIRFLIIAWNTGHFQRYDITAQCFRDAQLYH 437
            ....:|||..|:              .|...||.||:..   ..|||...:...|:.|.::.|
Zfish   419 SPAFELLPCGFV--------------MGEAGAEPRFMQF---HPHFQHGALLTVCWSDGRITH 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13137	NP_609350.2	WD40	89..357	CDD:295369	64/288 (22%)
		WD40	89..>333	CDD:225201	57/264 (22%)
		WD40 repeat	135..178	CDD:293791	10/44 (23%)
		WD40 repeat	191..229	CDD:293791	10/37 (27%)
		WD40 repeat	237..274	CDD:293791	9/40 (23%)
aaas	NP_998390.1	WD40	106..>401	CDD:225201	70/306 (23%)
		WD40	142..396	CDD:295369	64/287 (22%)
		WD40 repeat	146..180	CDD:293791	7/37 (19%)
		WD40 repeat	187..233	CDD:293791	12/50 (24%)
		WD40 repeat	237..273	CDD:293791	10/37 (27%)
		WD40 repeat	281..314	CDD:293791	9/35 (26%)
		WD40 repeat	321..370	CDD:293791	10/48 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470197at33208
OrthoFinder	1	1.000	-	-		FOG0005612
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14494
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950