DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13137 and Aladin

DIOPT Version :9

Sequence 1:	NP_609350.2	Gene:	CG13137 / 34349	FlyBaseID:	FBgn0032188	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001285049.1	Gene:	Aladin / 31881	FlyBaseID:	FBgn0030122	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	105/372 - (28%)
Similarity:	162/372 - (43%)	Gaps:	59/372 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 ERISQ---TRGWKTSVIRFIECHPSSSLMAFLTNDDVVLICDKNYDCPTK--IQSVRQKDTTCVA 138
            |||:|   ||.|..|.:|::..:.....:|....||||.|..|:....|.  ::|..|...||:|
  Fly   124 ERIAQFVETRDWLNSDVRYLAWNQHFFCLAVAGVDDVVRIYTKSSSATTATVLKSPSQTQITCMA 188

  Fly   139 FRPWSQTCEFAVGCAAGICLWSDSRRLNANRNIRRMMGTHHLQVLQDKGHNYVTSMQWNEDGTIL 203
            :||...: |..:||..|:|.|.....|:..|.      ....::.:...:..:||||||:|||.|
  Fly   189 WRPLCAS-EIVIGCRQGLCFWEVDSTLHLGRT------NAPSEIFKYPNNLPITSMQWNKDGTQL 246

  Fly   204 VTAAFGSSHIMLWEPD--CQQKIRLIPNPKSLGSFSLLRFSPDFHVLFCASCDAGASLCQLNRSK 266
            .||:.|...|::|:||  ..|.::.:..|.     |||::|||...||.|:.|....:
  Fly   247 ATASIGDRSIIIWQPDTGMMQPLKRLGPPG-----SLLKWSPDNDWLFAATVDRVFRV------- 299

  Fly   267 WKLKQILGQQR--------IQSAVWTTCGSTLLYACYGSTRVY-------SCTSDGEDSVFLRPQ 316
            |...|....:|        :|:|.|:.||..||:.......:|       |..|...|...:.|
  Fly   300 WNCHQQWTTERWVCGPGGYVQTACWSPCGRFLLFVSSAEPILYRLQFVQQSLLSSSADEKEILP- 363

  Fly   317 SIWRVQLIMDLQLVTTCAGQRLCCGEPQCLAMDPLGIYMASIFKEQSFVLLCILHTSRWGNVKLL 381
                   |.||...:..|.:.|..|..|.||.||.|.|:...||..:.:.:......::.    |
  Fly   364 -------IADLNACSIDANRTLVGGPAQQLAWDPHGNYLVVTFKATNCIAVFRTFIQKFD----L 417

  Fly   382 PVEFIYCDMDGD---QYPAYISFGVL--KAEIRFLIIAWNTGHFQRY 423
            .:...|. :.|:   ::|::|.|..|  ..:...|.|||::|..|.|
  Fly   418 QISAAYY-LSGETAAEHPSFICFQPLYEDNDRSVLTIAWSSGRIQYY 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13137	NP_609350.2	WD40	89..357	CDD:295369	82/286 (29%)
		WD40	89..>333	CDD:225201	72/262 (27%)
		WD40 repeat	135..178	CDD:293791	13/42 (31%)
		WD40 repeat	191..229	CDD:293791	18/39 (46%)
		WD40 repeat	237..274	CDD:293791	12/36 (33%)
Aladin	NP_001285049.1	WD40	<130..>420	CDD:225201	88/320 (28%)
		WD40 repeat	137..177	CDD:293791	10/39 (26%)
		WD40 repeat	184..227	CDD:293791	13/49 (27%)
		WD40 repeat	235..274	CDD:293791	18/38 (47%)
		WD40 repeat	276..312	CDD:293791	13/47 (28%)
		WD40 repeat	320..357	CDD:293791	10/36 (28%)
		WD40 repeat	364..400	CDD:293791	13/35 (37%)
		WD40 repeat	407..441	CDD:293791	6/38 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2139
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470197at33208
OrthoFinder	1	1.000	-	-		FOG0005612
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR14494
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850