DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and BCY1

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_012231.1	Gene:	BCY1 / 854778	SGDID:	S000001295	Length:	416	Species:	Saccharomyces cerevisiae

Alignment Length:	406	Identity:	114/406 - (28%)
Similarity:	174/406 - (42%)	Gaps:	85/406 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 QPEREMGKQQALQAPPRAKSSSNVSLNYLAKSQTDSQRRRRVSTMPDINIPPAPPLPPELLVPGT 332
            :||....:.|:.|:..|::||      .:.||             |.:|..|
Yeast    64 EPEESFSRPQSAQSQSRSRSS------VMFKS-------------PFVNEDP------------- 96

  Fly   333 PLHLRKKRSMERQQQQKQQEQQQQQEIQQDATNSQDQMAGAEESHKSSDSSTP---------KTH 388
              |....:|.......:|...||.||               |:.|....:|||         :..
Yeast    97 --HSNVFKSGFNLDPHEQDTHQQAQE---------------EQQHTREKTSTPPLPMHFNAQRRT 144

  Fly   389 RVEGGLIYVRPN---------FPIQSDIEIESIAKDEGTRNLIRTAIERNDFLNNLMDKERKEMV 444
            .|.|..:  :||         :..:|:.:::.:.|.           .||:||.|.:|.:.|.:|
Yeast   145 SVSGETL--QPNNFDDWTPDHYKEKSEQQLQRLEKS-----------IRNNFLFNKLDSDSKRLV 196

  Fly   445 INAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFGPATVFGELAILYNAPRQAS 509
            ||.:...|..|.:.||::.::|...||..:|..|.......|.|.||.:.|||||::||:||.|:
Yeast   197 INCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAAT 261

  Fly   510 IEAATDARVWKIARETFRAIMQISGSREREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETD 574
            :.|.:|..:|.:.|.|||.|:..|..::|......|:|.|.|:........|:.|.|..|.|:..
Yeast   262 VVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPG 326

  Fly   575 SCIVREGELGNEFYIIRCGTVTIKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPG 639
            ..|:|||:.|..||:|..|.|.:.|    :.:.::...|..|||||.||||...|||:|.| ...
Yeast   327 ETIIREGDQGENFYLIEYGAVDVSK----KGQGVINKLKDHDYFGEVALLNDLPRQATVTA-TKR 386

  Fly   640 TEVLMLDREAFISYLG 655
            |:|..|.:..|...||
Yeast   387 TKVATLGKSGFQRLLG 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	52/148 (35%)
		CAP_ED	431..539	CDD:237999	40/107 (37%)
		Crp	544..>650	CDD:223736	38/105 (36%)
		CAP_ED	550..663	CDD:237999	38/106 (36%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
BCY1	NP_012231.1	DD_R_PKA_fungi	7..44	CDD:213045
		CAP_ED	184..282	CDD:237999	37/97 (38%)
		CAP_ED	302..409	CDD:237999	38/106 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810