DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and TPK3

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_012755.1	Gene:	TPK3 / 853688	SGDID:	S000001649	Length:	398	Species:	Saccharomyces cerevisiae

Alignment Length:	393	Identity:	134/393 - (34%)
Similarity:	218/393 - (55%)	Gaps:	46/393 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   616 DYFGEQALLNADVRQASVYAD-APGTEVLMLDREAFISYLGTIKQ-------LREKPSSQRNDTS 672
            |..|:...:||.    ||:.: :..|.|.:..|.:     |.:|:       |.:||..|..|||
Yeast    25 DNVGQDIPVNAH----SVHEECSSNTPVEINGRNS-----GKLKEEASAGICLVKKPMLQYRDTS 80

  Fly   673 GRSSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVA--YNQQALALKIIKKIEVVKQDQIE 735
            |:.|              :|:.:.:.|||.|:||||.|:.  :|.:..|||.:||..:||..|:|
Yeast    81 GKYS--------------LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVE 131

  Fly   736 HVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCV 800
            |. |::..|:.....|||::::.|:::.:.|:.:|:...||::::::.|.|.|....|||.|..|
Yeast   132 HT-NDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 195

  Fly   801 VEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIILDR 865
            ..|.:||||...|||||||||::|..:|:.|:.||||||:|  .:.|.|..|||:|:|||::..:
Yeast   196 CLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV--PDVTYTLCGTPDYIAPEVVSTK 258

  Fly   866 GHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCKQL 930
            .::::||:|:.|:|:||:|.|.|||...|.:|.|:.||:.  .:..|......||.|::.|..:.
Yeast   259 PYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNA--ELKFPPFFHPDAQDLLKKLITRD 321

  Fly   931 PAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWT-DLQYFGPSGVENDYEPPE 994
            .:||||..:.|..|:|.|.||..:.|::|..:.:.:|.:.|::... |...|       |..|.|
Yeast   322 LSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQF-------DRYPEE 379

  Fly   995 ELS 997
            |.:
Yeast   380 EFN 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736
		CAP_ED	431..539	CDD:237999
		Crp	544..>650	CDD:223736	9/34 (26%)
		CAP_ED	550..663	CDD:237999	12/54 (22%)
		S_TKc	695..951	CDD:214567	101/257 (39%)
		STKc_cGK	700..957	CDD:270724	102/258 (40%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	111/301 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910