DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and prkar1b

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_001070091.1	Gene:	prkar1b / 767685	ZFINID:	ZDB-GENE-060929-580	Length:	380	Species:	Danio rerio

Alignment Length:	352	Identity:	106/352 - (30%)
Similarity:	171/352 - (48%)	Gaps:	38/352 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 RKKRSME--RQQQQKQQEQQQQQEIQQDATNSQDQMAGAEESHKSSDSSTP-----KTHRVEGG- 393
            :.:|.|:  |:..:|.::::.:|.:.:..:|||      .:||....|..|     |..|..||
Zfish    41 KPERPMKFLREHFEKLEKEECKQIMARQKSNSQ------SDSHDDEVSPPPPNPVVKARRRRGGV 99

  Fly   394 ----------LIYVRPNFPIQSDIEIESIAKDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAM 448
                      :.|||...|           ||..|...:..||.:|....:|.|.||.: :.:||
Zfish   100 SAEVYTEEDAVSYVRKVIP-----------KDYKTMTALAKAISKNVLFAHLDDNERSD-IFDAM 152

  Fly   449 APASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFGPATVFGELAILYNAPRQASIEAA 513
            .|.::.....:|::.:||...||..:|:.||...|:.|.|.|....|||||::|..||.|:::|.
Zfish   153 FPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTSIGEGGSFGELALIYGTPRAATVKAK 217

  Fly   514 TDARVWKIARETFRAIMQISGSREREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIV 578
            ||.::|.|.|:::|.|:..|..|:|:...:||.....|:..|:...|.|.|.|:...:|....||
Zfish   218 TDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIV 282

  Fly   579 REGELGNEFYIIRCGTVTIKKLDEQQQEQIVANR-KRGDYFGEQALLNADVRQASVYADAPGTEV 642
            .:||.|::|:||..||.::.:.....:|.:...| ...|||||.|||....|.|:|.|..| .:.
Zfish   283 VQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGP-LKC 346

  Fly   643 LMLDREAFISYLGTIKQLREKPSSQRN 669
            :.|||..|...||...::.::...:.|
Zfish   347 VKLDRPRFERVLGPCSEILKRNIQRYN 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	49/148 (33%)
		CAP_ED	431..539	CDD:237999	38/107 (36%)
		Crp	544..>650	CDD:223736	37/106 (35%)
		CAP_ED	550..663	CDD:237999	38/113 (34%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
prkar1b	NP_001070091.1	DD_RIbeta_PKA	10..63	CDD:213049	4/21 (19%)
		CAP_ED	136..245	CDD:237999	39/109 (36%)
		CAP_ED	254..369	CDD:237999	38/115 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910