Protein Alignment CG4839 and RPS6KA2

DIOPT Version :10

• Sequence 1: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: XP_006715612.1
• Gene: RPS6KA2 / 6196
• HGNCID: 10431
• Length: 761
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 105/331 - (31%)
• Similarity: 186/331 - (56%)
• Gaps: 17/331 - (5%)

  Fly   663 KPSSQRNDTSGRSSTKSLEFDNE----YSQVAISELKKIATLGCGAFGRVDLVAYNQ-----QAL 718
            :|.:|..:   ....|.::..:.    :.:...|:.:.:..||.|::|:|.||...:     |..
Human    55 EPETQHEE---EGVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLY 116

  Fly   719 ALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMS 783
            |:|::||..:..:|::.... |::::.:... ||||:|:..::.:..:|.:::...|||::|.:|
Human   117 AMKVLKKATLKVRDRVRSKM-ERDILAEVNH-PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 179

  Fly   784 KRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAK-FVRQNEKT 847
            |...|.|:..||....:..|.|:|||...|||||||||::|..:|:.|:.|||.:| .:..:::.
Human   180 KEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 244

  Fly   848 NTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMP 912
            .:|.||.||:|||::..|||.::.|:|:.|:|::|:|.|..||:|.::.:....||..  .:.||
Human   245 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA--KLGMP 307

  Fly   913 SRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTD 977
            ..:...||.|:|.|.|:.|..|||....|:.:||||.:|.::||..|..|::..|.|..:....|
Human   308 QFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPED 372

  Fly   978 LQYFGP 983
            ..:|.|
Human   373 TFHFDP 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999
		CAP_ED	550..663	CDD:237999	105/331 (32%)
		STKc_cGK	700..957	CDD:270724	93/262 (35%)
RPS6KA2	XP_006715612.1	STKc_RSK_N	91..407	CDD:270734	101/292 (35%)
		STKc_RSK3_C	439..731	CDD:271080