Protein Alignment CG4839 and RPS6KA1

DIOPT Version :10

• Sequence 1: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: NP_001006666.1
• Gene: RPS6KA1 / 6195
• HGNCID: 10430
• Length: 744
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 110/330 - (33%)
• Similarity: 184/330 - (55%)
• Gaps: 18/330 - (5%)

  Fly   664 PSS--QRNDTSG----RSSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAY-----NQQA 717
            |.|  ||:...|    .|.|..::..:|.:..:..||.|:  ||.|:||:|.||..     :...
Human    37 PGSGPQRDSDEGVLKEISITHHVKAGSEKADPSHFELLKV--LGQGSFGKVFLVRKVTRPDSGHL 99

  Fly   718 LALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVM 782
            .|:|::||..:..:|:: ....|::::..... ||:|:|:..::.:..:|.:::...|||::|.:
Human   100 YAMKVLKKATLKVRDRV-RTKMERDILADVNH-PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 162

  Fly   783 SKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAK-FVRQNEK 846
            ||...|.|:..||....:....|:|||...|||||||||::|..:|:.||.|||.:| .:...:|
Human   163 SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKK 227

  Fly   847 TNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHM 911
            ..:|.||.||:|||::..:||..:.|:|:.|:|::|:|.|..||:|.::.:....||..  .:.|
Human   228 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA--KLGM 290

  Fly   912 PSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWT 976
            |..:...||.|:|.|.|:.||.|||....|..:||||.::.::||.:|..:::..|.|..:....
Human   291 PQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPD 355

  Fly   977 DLQYF 981
            |..||
Human   356 DTFYF 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999
		CAP_ED	550..663	CDD:237999
		STKc_cGK	700..957	CDD:270724	92/262 (35%)
RPS6KA1	NP_001006666.1	STKc_RSK_N	75..391	CDD:270734	100/292 (34%)
		STKc_RSK1_C	425..715	CDD:271077