DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4839 and akt3a

DIOPT Version :10

Sequence 1:NP_609349.1 Gene:CG4839 / 34348 FlyBaseID:FBgn0032187 Length:1003 Species:Drosophila melanogaster
Sequence 2:NP_001184130.1 Gene:akt3a / 560549 ZFINID:ZDB-GENE-050419-180 Length:479 Species:Danio rerio


Alignment Length:436 Identity:128/436 - (29%)
Similarity:215/436 - (49%) Gaps:50/436 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   585 NEFYIIRCGTVTIKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREA 649
            |.|.:.:|             :.:...|.:.:.|..:.|....|.:.:.:.|.|.      :|:.
Zfish    52 NNFSVAKC-------------QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPE------ERDE 97

  Fly   650 FISYLGTIKQLREKPSSQRNDTSGRSSTKSL---EFD---NEYSQVAISELKKIATLGCGAFGRV 708
            :...:..:....::...:|...|..|...::   |.|   :.:.:..:::...:..||.|.||:|
Zfish    98 WAEAIQMVADKLQRQEEERIQCSPTSQIDNMGEEEMDTSISHHKRKTMNDFDYLKLLGKGTFGKV 162

  Fly   709 DLVAYNQQA--LALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLME 771
            .||......  .|:||:||..::.:|::.|...|..| :|..:.||:..|..:::....:.|:||
Zfish   163 ILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRV-LKNTRHPFLTSLKYSFQTKDRLCFVME 226

  Fly   772 ACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFG 836
            ...||:::..:|:.:.|.|...:|....:|.|.|||||...:|||||.|||||..||:.|:.|||
Zfish   227 YVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFG 291

  Fly   837 FAK-FVRQNEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQ 900
            ..| .:.......||.|||||:|||::.|..:.||||:|.||:::||::.|:.||...:..|:::
Zfish   292 LCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFE 356

  Fly   901 QILSGIDVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLP 965
            .||  ::.|..|..:...|:.|:..|..:.|.:|||.......:|.|||:|..:|||.:..|:|.
Zfish   357 LIL--MEDIKFPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTGIDWQDVYDKKLI 419

  Fly   966 SPIKRPLKSWTDLQYFGPSGVENDYE---------PPEELSGWDKD 1002
            .|.|..:.|.||.:||       |.|         |||:   :|:|
Zfish   420 PPFKPQVSSETDTRYF-------DEEFTAQTITITPPEK---FDED 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4839NP_609349.1 CAP_ED 431..539 CDD:237999
CAP_ED 550..663 CDD:237999 10/77 (13%)
STKc_cGK 700..957 CDD:270724 95/259 (37%)
akt3aNP_001184130.1 PH_PKB 4..110 CDD:269947 10/76 (13%)
STKc_PKB_gamma 132..479 CDD:270745 115/337 (34%)
Blue background indicates that the domain is not in the aligned region.

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