DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4839 and PRKACG

DIOPT Version :9

Sequence 1:NP_609349.1 Gene:CG4839 / 34348 FlyBaseID:FBgn0032187 Length:1003 Species:Drosophila melanogaster
Sequence 2:NP_002723.2 Gene:PRKACG / 5568 HGNCID:9382 Length:351 Species:Homo sapiens


Alignment Length:306 Identity:124/306 - (40%)
Similarity:187/306 - (61%) Gaps:17/306 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   693 ELKKIATLGCGAFGRVDLVAYNQQA--LALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQ 755
            :.:::.|||.|:||||.||.:.:..  .|:||:.|.:|||..|:||:.|||.: ::....||:|:
Human    43 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRI-LQAIDFPFLVK 106

  Fly   756 LYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPE 820
            |..:::::.|:|.:||...||::::.:.:...|.|..|.|.|..||.|..||||...|:||||||
Human   107 LQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPE 171

  Fly   821 NLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLV 885
            ||::...||.::.||||||  |...:|.|..|||||:||||||.:|:::|||:||||:|:||:.|
Human   172 NLLIDQQGYLQVTDFGFAK--RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAV 234

  Fly   886 GKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSW 950
            |..||.....|:||::|:||  .:..||::....:||:|.|.:....:|.|..|.|:.|||.|.|
Human   235 GFPPFYADQPIQIYEKIVSG--RVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKW 297

  Fly   951 FESLDWQRLKLKQLPSPIKRPLKSWTDLQYFGPSGVEN--DYEPPE 994
            |.:..|..:..|::.:|...        :|.||....|  |||..|
Human   298 FATTSWIAIYEKKVEAPFIP--------KYTGPGDASNFDDYEEEE 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4839NP_609349.1 Crp 428..577 CDD:223736
CAP_ED 431..539 CDD:237999
Crp 544..>650 CDD:223736
CAP_ED 550..663 CDD:237999
S_TKc 695..951 CDD:214567 111/257 (43%)
STKc_cGK 700..957 CDD:270724 112/258 (43%)
PRKACGNP_002723.2 PTZ00426 36..351 CDD:173616 124/306 (41%)
STKc_PKA 42..331 CDD:271111 120/300 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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