Protein Alignment CG4839 and prkg2l

DIOPT Version :10

• Sequence 1: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: XP_021336392.1
• Gene: prkg2l / 556339
• ZFINID: ZDB-GENE-090902-1
• Length: 771
• Species: Danio rerio
• Alignment Length: 857
• Identity: 312/857 - (36%)
• Similarity: 446/857 - (52%)
• Gaps: 167/857 - (19%)

  Fly   208 DTPSSNSIATTPVTEG--PVKFFIGHTQELSAQQTDDTLSCQSSDANNNSAAKLTNGVVPQEQPE 270
            :|..::||..|||.|.  |:|..|.|.:|..|::                              :
Zfish    21 ETCLASSIKETPVWESVEPLKMRIAHLEEELARR------------------------------D 55

  Fly   271 REMGKQ----QALQAPPRAKSS------SNVSLNYLAKSQTDSQRRRRVSTMPDINIPPAPPLPP 325
            ||:..|    |:||....||.|      ..:..|.|.:|                  ||||
Zfish    56 RELRAQENQLQSLQRELEAKVSQIDKLQDAIGYNSLGRS------------------PPAP---- 98

  Fly   326 ELLVPGTPLHLRKKRSMERQQQQKQQEQQQQQEIQQDATNSQDQMAGAEESH-----KSSDSSTP 385
                   ..|.|:..|:..|...:....                   |.|.|     |...|:.|
Zfish    99 -------LRHSRRLLSVINQGSMRFHRV-------------------AVEVHRRLKAKEGVSAEP 137

  Fly   386 KT------HRVEGGLIYVRPNFPIQSDIEIESIAKDEGTRNLIRTAIERNDFLNNLMDKERKEMV 444
            .|      ||..            :|..|.:.|.||.||:.||..|:.:||||..|..:..:|||
Zfish   138 TTRHFCHDHRAH------------RSSTERQHIRKDSGTKKLINEALMKNDFLKKLEPQHTREMV 190

  Fly   445 INAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFGPATVFGELAILYNAPRQAS 509
             :.|....|....|:|:|.|.|:.:||.|||..:||:.|:.:....|.|.|||||||||..|.|:
Zfish   191 -DCMYEKIYGAEQLVIQEGEPGNFLYVLAEGLLEVIQNGKFLGQMRPGTAFGELAILYNCKRTAT 254

  Fly   510 IEAATDARVWKIARETFRAIMQISGSREREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETD 574
            ::|.:.:.:|.:.|:||:.||..|.....||...||||...|::..:..|.|::|.|:..:::..
Zfish   255 VKAVSQSHIWALDRQTFQTIMMRSTQARHEEYFSFLRSVSLLKDLPEEKLAKIIDCLEIDYFDKG 319

  Fly   575 SCIVREGELGNEFYIIRCGTVTIKKLDEQQQE-QIVANRKRGDYFGEQALLNADVRQASVYADAP 638
            ..|:||||.||.|:||..|.|::.:..|...| |.:...:.||||||:||::.|||.|::.|...
Zfish   320 EYIIREGEEGNTFFIIAKGEVSVTQTTEGFTEPQEIKTLRVGDYFGEKALISEDVRSANIIAKEN 384

  Fly   639 GTEVLMLDREAFISYLGTIKQLR---------------------EKPSSQRNDTSGR-------- 674
            .|:.|::||:.|...:||.::|:                     :.|..:|:..:..
Zfish   385 DTQCLVVDRDNFNEMVGTYEELQAYLREYVEELSLSDERRNAVPQSPLYERSPEAAELRRLKEKA 449

  Fly   675 ---SSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAYNQQ---ALALKIIKKIEVVKQDQ 733
               |||..|:           ||:.:||||.|.||||:||.....   |.|||.|||..:|...|
Zfish   450 TALSSTSFLK-----------ELQVVATLGMGGFGRVELVKLKDSEDTAFALKCIKKKHIVDTRQ 503

  Fly   734 IEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAG 798
            .||:|:|| ::::...|.|||:|:||:|:||:||.|:|.|:||::|:::.....|||.||:|..|
Zfish   504 QEHIYSEK-IILQQTNSNFIVRLFRTFRDDKFVYMLLEVCLGGELWSLLRDMSCFDEPTARFCTG 567

  Fly   799 CVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIIL 863
            ||:|||||||....:|||||||||:|..:||.|:.||||||.:...:||.||.|||||||||:|:
Zfish   568 CVLEAFDYLHGKGIVYRDLKPENLLLDAEGYVKMADFGFAKKIGLGKKTWTFCGTPEYVAPEVIM 632

  Fly   864 DRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCK 928
            ::|||...|.|:||||::|||:|..||.|.:.|:||..:|.||:.:.:|.||.|..:.|:|.|||
Zfish   633 NKGHDFGADCWSLGILIFELLIGSPPFTGSDPIRIYTMVLHGIEKVDIPKRISKRPEDLIRRLCK 697

  Fly   929 QLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQYFG--PSGVENDYE 991
            ..||||||.::.||.|||:|.||:..:|:.|:.::|.||::|.||...|..||.  |..:|   |
Zfish   698 LNPAERLGNKKNGIIDIKKHKWFQGFNWEGLRRRKLMSPLRRELKGPLDHSYFDMFPPELE---E 759

  Fly   992 PPEELSGWDKDF 1003
            ||:|.|||||||
Zfish   760 PPDEFSGWDKDF 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999	42/107 (39%)
		CAP_ED	550..663	CDD:237999	41/134 (31%)
		STKc_cGK	700..957	CDD:270724	135/259 (52%)
prkg2l	XP_021336392.1	CAP_ED	177..286	CDD:237999	43/109 (39%)
		CAP_ED	295..410	CDD:237999	41/114 (36%)
		STKc_cGK	467..727	CDD:270724	136/260 (52%)