DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4839 and prkar1ab

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_001017732.1	Gene:	prkar1ab / 550427	ZFINID:	ZDB-GENE-050417-238	Length:	379	Species:	Danio rerio

Alignment Length:	345	Identity:	99/345 - (28%)
Similarity:	167/345 - (48%)	Gaps:	19/345 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 PGTPLHLRKKRSMERQQQQKQQEQQQQQEIQQDATNSQDQ----MAGAEESHKSSDSSTPKTHRV 390
            |..|:...:: ..||.::::.::...||:....:.:.:|:    |....:..:...:.:.:.:..
Zfish    42 PDRPMAFLRE-YFERLEKEESKQLLNQQKASSRSDSREDEVSPPMNPVVKGRRRRGAISAEVYTE 105

  Fly   391 EGGLIYVRPNFPIQSDIEIESIAKDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRK 455
            |....|||...|           ||..|...:..|||:|...::|.|.||.: :.:||.|.:|..
Zfish   106 EDAASYVRKVIP-----------KDYKTMAALAKAIEKNVLFSHLDDNERSD-IFDAMFPVTYIA 158

  Fly   456 HSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFGPATVFGELAILYNAPRQASIEAATDARVWK 520
            ..::|::.:||...||..:|:.||....:...|.|....|||||::|..||.|::.|.|:.::|.
Zfish   159 GEIVIQQGDEGDNFYVIDQGEMDVYVNSEWATSIGEGGSFGELALIYGTPRAATVRAKTNVKLWG 223

  Fly   521 IARETFRAIMQISGSREREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGN 585
            |.|:::|.|:..|..|:|:...:||.....|:..|:...|.|.|.|:...:|....||.:||.|:
Zfish   224 IDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDSQKIVVQGEPGD 288

  Fly   586 EFYIIRCGTVTIKKLDEQQQEQIVANR-KRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREA 649
            ||:||..|...:.:...:.:|.:...| ...|||||.|||....|.|:|.|..| .:.:.|||..
Zfish   289 EFFIILEGCAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGP-LKCVKLDRPR 352

  Fly   650 FISYLGTIKQLREKPSSQRN 669
            |...||....:.::...|.|
Zfish   353 FERVLGPCSDILKRNIQQYN 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	47/148 (32%)
		CAP_ED	431..539	CDD:237999	36/107 (34%)
		Crp	544..>650	CDD:223736	37/106 (35%)
		CAP_ED	550..663	CDD:237999	38/113 (34%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
prkar1ab	NP_001017732.1	DD_RIalpha_PKA	13..62	CDD:213048	4/20 (20%)
		Crp	129..>255	CDD:223736	43/126 (34%)
		CAP_ED	135..244	CDD:237999	37/109 (34%)
		Crp	247..>357	CDD:223736	38/110 (35%)
		CAP_ED	253..368	CDD:237999	38/115 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910